Methods of treating inflammation in neuronal tissue
First Claim
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1. A method of treating neuronal tissue inflammation in a mammal comprising administering to the mammal a monoclonal antibody or binding fragment thereof which specifically binds to a polypeptide sequence of amino acid residues 27-164 of SEQ ID NO:
- 2, and wherein after administration the neuronal tissue inflammation is reduced.
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Abstract
Use of antagonists to IL-31 are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.
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7 Claims
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1. A method of treating neuronal tissue inflammation in a mammal comprising administering to the mammal a monoclonal antibody or binding fragment thereof which specifically binds to a polypeptide sequence of amino acid residues 27-164 of SEQ ID NO:
- 2, and wherein after administration the neuronal tissue inflammation is reduced.
- View Dependent Claims (2, 3, 4, 5, 6, 7)
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