Umbilical cord biomaterial for medical use
First Claim
1. An umbilical cord-derived biomaterial comprising an isolated mammalian umbilical cord membrane, from which the vessels have been removed, and Wharton'"'"'s jelly, wherein said biomaterial comprises less than 20% water by weight.
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Abstract
The present invention provides a biomaterial comprising a mammalian umbilical cord membrane. The biomaterial can additionally comprise Wharton'"'"'s jelly and/or one or more umbilical cord vessels. The biomaterial is preferably dry, and can be flat, tubular, or shaped to fit a particular body structure. The invention further provides laminates comprising at least one layer of an umbilical cord membrane biomaterial. The invention further provides methods of making the biomaterial, and laminates comprising the biomaterial, and methods of using the biomaterial.
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18 Claims
- 1. An umbilical cord-derived biomaterial comprising an isolated mammalian umbilical cord membrane, from which the vessels have been removed, and Wharton'"'"'s jelly, wherein said biomaterial comprises less than 20% water by weight.
- 12. An umbilical cord-derived biomaterial comprising an isolated mammalian umbilical cord membrane and Wharton'"'"'s jelly, wherein said biomaterial comprises less than 20% by weight, and wherein the biomaterial is decellularized.
- 14. An umbilical cord-derived biomaterial comprising an isolated mammalian umbilical cord membrane and Wharton'"'"'s jelly, wherein said biomaterial comprises less than 20% water by weight, and wherein the biomaterial additionally comprising an exogenous stem cell.
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17. A laminate comprising a plurality of layers, wherein at least one of the layers comprises an umbilical cord-derived biomaterial comprising an isolated mammalian umbilical cord membrane and Wharton'"'"'s jelly, wherein said biomaterial comprises less than 20% water by weight.
Specification