Methods, devices, kits and compositions for detecting roundworm
First Claim
1. A method for specifically detecting the presence or absence of one or more roundworm Toxocara antigens in a sample, the method comprising:
- (a) contacting a sample from a mammal with one or more antibodies that specifically bind to a polypeptide selected from the group consisting of SEQ ID NO;
3, SEQ ID NO;
4, SEQ ID NO;
5, SEQ ID NO;
6, and SEQ ID NO;
7 to form antibody-polypeptide complexes in the presence of the polypeptides if any, in the sample, and(b) detecting the presence or absence of the antibody-polypeptide complexes, if any.
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Accused Products
Abstract
Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
44 Citations
24 Claims
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1. A method for specifically detecting the presence or absence of one or more roundworm Toxocara antigens in a sample, the method comprising:
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(a) contacting a sample from a mammal with one or more antibodies that specifically bind to a polypeptide selected from the group consisting of SEQ ID NO;
3, SEQ ID NO;
4, SEQ ID NO;
5, SEQ ID NO;
6, and SEQ ID NO;
7 to form antibody-polypeptide complexes in the presence of the polypeptides if any, in the sample, and(b) detecting the presence or absence of the antibody-polypeptide complexes, if any. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for specifically diagnosing whether a mammal is infected with an intestinal roundworm Toxocara infection, the method comprising the steps of:
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(a) contacting a sample from a mammal with one or more antibodies that specifically bind to a polypeptide selected from the group consisting of SEQ ID NO;
3, SEQ ID NO;
4, SEQ ID NO;
5, SEQ ID NO;
6 and SEQ ID NO;
7;
to form antibody-polypeptide complexes in the presence of the polypeptides if any, in the sample, and(b) diagnosing the mammal as having the roundworm Toxocara infection if a roundworm antibody-polypeptide complex is present. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification