Enzymatic synthesis of acetoacetate esters and derivatives
First Claim
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1. A method for the synthesis of an ester derivative of acetoacetate, comprising providing a first ester of acetoacetate having of formula I:
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Abstract
In one embodiment, the present invention includes a method for the synthesis of an ester derivative of acetoacetate. The method includes providing a first ester of acetoacetate and providing an alcohol. The method further includes combining the first ester of acetoacetate and the alcohol in the presence of an enzyme capable of transesterification in a non-aqueous solvent to form the ester derivative of acetoacetate. The method results in the formation of the ester derivative of acetoacetate, which, in one embodiment, is monoacetoacetin.
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5 Claims
- 1. A method for the synthesis of an ester derivative of acetoacetate, comprising providing a first ester of acetoacetate having of formula I:
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