Blood monitoring systems and methods thereof
First Claim
1. A blood monitoring system comprising:
- a substrate with one or more wells;
one or more needles with one of the needles in each of the wells;
an actuating system that moves the needles at least partially out of the wells when activated;
one or more sensors, with one of the sensors on each of the needles wherein at least one of the sensors comprises a glucose responsive magnetic material on a mechanically resonant nonmagnetic layer;
a detection system that reads an output of at least one of the sensors; and
a control system that controls the activation of the actuating system and the reading of an output from at least one of the sensors by the detection system.
2 Assignments
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Accused Products
Abstract
A blood monitoring system is capable of monitoring the blood of a subject in vivo. The blood monitoring system comprises: 1) an array of movable microneedle micromachined within associated wells; 2) array of motion actuators able to move each needle in and out of their associated wells; 3) array of microvalves associated with each microneedle able to control the flow of air around the microneedle; 4) an array of chemical sensors inserted into patient by movable microneedles; 5) an array of inductors able to measure chemical concentration in the vicinity of inserted chemical sensors; 6) conducting vias that provide timed actuating signal signals from a control system to each motion actuator; 7) conducting vias that transmit signal produced by array of chemical sensors to the control system for processing, although the blood monitoring system can comprise other numbers and types of elements in other configurations.
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Citations
28 Claims
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1. A blood monitoring system comprising:
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a substrate with one or more wells; one or more needles with one of the needles in each of the wells; an actuating system that moves the needles at least partially out of the wells when activated; one or more sensors, with one of the sensors on each of the needles wherein at least one of the sensors comprises a glucose responsive magnetic material on a mechanically resonant nonmagnetic layer; a detection system that reads an output of at least one of the sensors; and a control system that controls the activation of the actuating system and the reading of an output from at least one of the sensors by the detection system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method for making a blood monitoring system, the method comprising:
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forming one or more needles in a substrate with a well around each of the needles; providing an actuating system that move the needles at least partially out of the wells when activated; providing one or more sensors on each of the needles; positioning a detection system to read an output of at least one of the sensors wherein at least one of the sensors comprises a glucose responsive magnetic material on a mechanically resonant nonmagnetic layer; and providing a control system that controls the activation of the actuating system and the reading of an output from at least one of the sensors by the detection system. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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Specification