MRI systems having MRI compatible universal delivery cannulas with cooperating MRI antenna probes and related systems and methods
First Claim
Patent Images
1. An in vivo deep brain medical probe system, comprising:
- an MRI compatible cannula comprising a plurality of generally concentric axially extending tubes with a receiving bore;
an elongate antenna member with a core comprising a conductor and an insulating layer configured to slidably advance through the cannula bore to cooperate with the cannula to define an MRI receive antenna, wherein the elongate antenna member comprises a center conductor and at least one recording electrode disposed on a distal portion thereof, wherein the probe system has at least two operational modes, including a first MRI signal operational mode wherein the antenna member receives MRI signals from local tissue and a second operational recording signal mode wherein the recording electrode obtains electrical signals from local target tissue;
a tuning circuit coupleable to the MRI receive antenna to tune the MRI receive antenna to a MRI frequency;
a RF decoupling circuit configured to isolate the MRI receive antenna during an MRI excitation RF transmission; and
a recording splitter circuit to decouple the MRI receive antenna during the recording mode.
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Accused Products
Abstract
In vivio deep brain medical probe systems include: (a) an NMRI compatible cannula comprising a plurality of concentric axially extending tubes with a receiving bore; and (b) an elongate antenna member with a conductor and an insulating layer configured to slidably advance through cannula bore to define an MRI receive antenna.
106 Citations
27 Claims
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1. An in vivo deep brain medical probe system, comprising:
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an MRI compatible cannula comprising a plurality of generally concentric axially extending tubes with a receiving bore; an elongate antenna member with a core comprising a conductor and an insulating layer configured to slidably advance through the cannula bore to cooperate with the cannula to define an MRI receive antenna, wherein the elongate antenna member comprises a center conductor and at least one recording electrode disposed on a distal portion thereof, wherein the probe system has at least two operational modes, including a first MRI signal operational mode wherein the antenna member receives MRI signals from local tissue and a second operational recording signal mode wherein the recording electrode obtains electrical signals from local target tissue; a tuning circuit coupleable to the MRI receive antenna to tune the MRI receive antenna to a MRI frequency; a RF decoupling circuit configured to isolate the MRI receive antenna during an MRI excitation RF transmission; and a recording splitter circuit to decouple the MRI receive antenna during the recording mode. - View Dependent Claims (2, 3, 4, 5, 6, 7, 18, 19)
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8. An in vivo deep brain medical probe system, comprising:
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an MRI compatible cannula comprising a plurality of generally concentric axially extending tubes with a receiving bore; an elongate antenna member with a core comprising a conductor and an insulating layer configured to slidably advance through the cannula bore to cooperate with the cannula to define an MRI receive antenna; and a tuning circuit coupleable to the MRI receive antenna to tune the MRI receive antenna to a MRI frequency, wherein the elongate antenna member comprises a flexible elongate inner member body having opposing proximal and distal portions, the inner member body comprising at least one recording electrode disposed on the distal portion; the MRI compatible cannula having increased rigidity relative to the elongate antenna member; the probe system further comprising an RF transmit decoupling circuit in communication with the elongate antenna member with the decoupler circuit configured to decouple the MRI receive antenna during an MRI RF excitation transmission; and a splitter circuit in communication with the elongate antenna member to electrically isolate a recording circuit from an MRI imaging circuit. - View Dependent Claims (9, 10, 11, 12, 13)
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14. A medical kit, comprising:
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(a) an elongate sterilized bio and MRI compatible internal MRI-antenna probe member having opposing distal and proximal portions, the MRI-antenna probe member comprising a core with a conductor and at least one recording electrode disposed on the distal portion of the MRI- antenna probe member, wherein the MRI-antenna probe member has at least two operational modes, including a first MRI signal operational mode wherein an antenna portion of the MRI-antenna probe member receives MRI signals from local tissue and a second operational recording signal mode wherein the recording electrode obtains electrical signals from local target tissue; (b) a generally rigid cannula comprising at least two generally concentric tubular members sized and configured to slidably receive the elongate MRI-antenna probe member therein, wherein, in operation, the MRI-antenna probe member cooperates with the cannula to define an internal MRI antenna; (c) a tuning circuit coupleable to the internal MRI antenna to tune the internal MRI antenna to a MRI frequency; (d) a RF decoupling circuit configured to isolate the MRI-antenna probe member during an MRI excitation RF transmission; and (e) a recording splitter circuit to decouple the antenna portion of the MRI-antenna probe member during the recording mode. - View Dependent Claims (15, 16, 17)
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20. An in vivo deep brain medical probe system, comprising:
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an MRI compatible cannula comprising a plurality of generally concentric axially extending tubes with a receiving bore; an elongate antenna member with a core comprising a conductor and an insulating layer configured to slidably advance through the cannula bore to cooperate with the cannula to define an MRI receive antenna; a tuning circuit coupleable to the MRI receive antenna to tune the MRI receive antenna to a MRI frequency, the elongate antenna member having opposing proximal and distal portions and comprising at least one optic fiber in the core of the antenna member; the cannula having increased rigidity relative to the antenna member; and the probe system further comprising an RF transmit decoupling circuit in communication with the antenna member, wherein the decoupler circuit is configured to decouple the MRI receive antenna during an MRI RF excitation transmission. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27)
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Specification