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Assessing autonomic activity using baroreflex analysis

  • US 8,109,879 B2
  • Filed: 01/10/2006
  • Issued: 02/07/2012
  • Est. Priority Date: 01/10/2006
  • Status: Active Grant
First Claim
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1. An apparatus capable of being implanted in a patient'"'"'s body, comprising:

  • a posture sensor;

    a source of blood pressure data;

    a heart rate sensor; and

    a processor coupled to the posture sensor and the heart rate sensor, the processor configured to;

    measure the patient'"'"'s heart rate via the heart rate sensor;

    detect a change in a posture of the patient'"'"'s body via the posture sensor; and

    determine an autonomic tone of the patient'"'"'s body based on the patient'"'"'s heart rate measured during a time period corresponding to the change in posture;

    wherein the processor is configured to determine the autonomic tone by performing a baroreflex sensitivity analysis (BSA) based on the heart rate and blood pressure measured during the time period; and

    wherein performing the BSA comprises determining a rate of change of systolic blood pressure relative to heart beat intervals during the time period corresponding to the change in posture.

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