WAN-based remote mobile monitoring method and device of electrophysiological data

• US 8,111,151 B2
• Filed: 01/15/2007
• Issued: 02/07/2012
• Est. Priority Date: 01/17/2006
• Status: Active Grant

• Current Assignee: Shanghai LEPU Cloudmed Company Limited
• Original Assignee: Haiqing Gao, Qichun Chen, Shiang Sun, Xiaohong Zhu, Yonggang Zhao
• Inventors: Zhu, Xiaohong, Gao, Haiqing, Zhao, Yonggang, Chen, Qichun, Sun, Shiang
• Primary Examiner(s): Afshar, Kamran
• Assistant Examiner(s): ROD, YOUSEF R
• Application Number:
  US12/087,725
• Publication Number:
  US 20100240980A1
• Time in Patent Office: 1,849 Days
• Field of Search: 340/539.12, 702/19, 702/22, 600/300, 600/301, 600/481, 455/552.1, 455/553.1, 455/423
• US Class Current: 340/539.12
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: Y02D 30/70 in wireless communication networks

Abstract

A WAN-based remote mobile monitoring method and device of electrophysiological data, including microprocessor circuit, electrophysiological signal sampling processing circuit, data storage circuit, image liquid crystal circuit, real-time clock, emergent calling circuit, working power supply management circuit, wireless network interface circuit, USB interface circuit, etc, has the in-built binding IP address of the remote electrophysiological data monitoring server, TCP/IP protocol, PPP protocol and BlueTooth protocol. Application controls self-adaptive analysis computing, exception event warning and alarming privilege graded setting, event data package combination, network digital communication, data storage circuit area management, safety information data storage management and remote emergent calling of the remote mobile monitoring devices. It can have access to Internet in motion and roaming access to Internet by inter-network switch, and have access to the exterior networks wirelessly including Internet, LAN, ADSL, VDSL, ISDN, etc, for digital communication with the remote electrophysiological data monitoring server.

Claims

1. A Wide Area Network (WAN)-based remote mobile monitoring device for electrophysiological data comprising:

a microprocessor connecting and controlling functional module circuits of said remote monitoring device to make early-warning for monitoring of electrophysiological data, to save data and to establish digital communication of network;

an electrophysiological signal processor to collect electrophysiological data, said electrophysiological signal processor comprising an internal calibration voltage signal circuit to provide a benchmark calibration voltage;

a data memory circuit comprising five data storage areas storing various data of said remote mobile monitoring;

said data storage areas including text storage area, setting information storage area, safety information storage area, abnormal electrophysiological data storage area, and continuous electrophysiological data storage area;

an image liquid crystal circuit displaying waveform, image symbols of electrophysiological data and texts with various languages;

a real-time clock circuit displaying date and time when the data being saved;

a wireless network interface circuit being built-in Transmission Control Protocol/Internet Protocol (TCP/IP), Point-to-Point Protocol (PPP), short-range communications, which are wirelessly able to access exterior network terminal interface to connect WAN with said digital communication of network;

an emergent calling circuit transmitting an emergent triggering signal to said microprocessor which commands said wireless network interface circuit to transmit helping request to desired receiving ends;

a power supply management circuit supplying electricity for various functional modules of said remote mobile monitoring under the control of said microprocessor;

a mechanical vibration and buzzer circuit conducting mechanical vibration and sound for alarm when warning flags being occurred under the control of said microprocessor;

a Universal Serial Bus (USB) interface circuit being utilized to exchange data between said remote mobile monitoring device and exterior devices, and to download the electrophysiological data of continuous monitoring from said remote mobile monitoring device.

2. The WAN-based remote mobile monitoring device for electrophysiological data according to claim 1, wherein said microprocessor comprising a low-power monolithic processor to connect Input/Output (I/O) port, exterior interruption source, serial communication port and internal Analog-to-Digital (A/D) analog converter to various functional modules, respectively;

whose universal flash programming utility being installed with software application;

said low-power monolithic processor is a monolithic processor M302280 or HD64F3847.

3. The WAN-based remote mobile monitoring device for electrophysiological data according to claim 2, wherein said internal calibration voltage signal circuit comprising a precision benchmark resource, a triode 9013, current limiting resistors, precision voltage division resistors;

base of said triode 9013 being connected to P1.3 of P1 port, emitter of said triode 9013 being connected to +3.3V power supply port of main circuit, and collector of said triode 9013 being connected to ground and negative electrode of said precision benchmark resource via two said current limiting resistors, respectively;

two said precision voltage division resistors being in series in which one end being connected to the negative electrode of said precision benchmark resource, another end being connected to ground and the middle end being connected to output end of a blocking circuit;

at the output end, said benchmark calibration voltage being 1 mv×

multiple of preamplifier stage with deviation error less than ±

1%.

4. The WAN-based remote mobile monitoring device for electrophysiological data according to claim 2, wherein said storage circuit consisting of a storage microprocessor and a memory data storage device;

said storage microprocessor being a storage monolithic processor which is a monolithic processor M30208;

said memory data storage device is a memory card is NAND01G;

P0.0-P0.7 of P0 of M30280 being connected to the data lines D0-D7 of NAND01G, respectively, and P2.2-P2.4 of P2 of M30280 being connected to chip selection end E, address locking end AL and command locking end CL of NAND01G, respectively;

or said memory card is K9K1GU0B, TC58DVG02A1 FT00 or RC28F13C-150 whose pins being connected with these of said storage monolithic processor by labels.

5. The WAN-based remote mobile monitoring device for electrophysiological data according to claim 2, wherein said wireless network interface circuit comprising an interface microprocessor which is a monolithic processor M30208, a network processing circuit IP2022, and a short-range communication integrated circuit which is BlueCore313143;

the series communication ports, TXD, RXD, CTS, DSR, of said processor M30280 being connected to the series communication 1 of said network processing circuit IP2022;

P5.O-P5.2 of P5 port of said processor M30280 being connected to reset end, state control end PRG, sleeping control end ON/OFF, respectively;

PORTSEI end, SLEEP_ENABLE end, HOST_INT end and DISCONNECT end of said network processing circuit IP2022 series communication 2 being connected to the UART_RX end, UART_TX end, UART_RTS end and UART_CTS end of said BlueCore313143, respectively;

the PORTSEI end, SLEEP_ENABLE end, HOST_INT end, DISCONNECT end of IP2022 being connected to the reset end RESET, power supply control VREG_EN end, wakeup end PWR_UP disconnection end DISCONNECT_CON of said BlueCore313143;

said short-range communication integrated circuit is BCM2035, BRF6100/6150 or MC72000 whose pins are connected by labels.

6. A WAN-based remote mobile monitoring method for electrophysiological data comprising the following steps operated by a software application:

step1;

the calibration voltages and accumulating samplings being used to compute current electrophysiological data to obtain initial data;

if said initial data being in setting range of threshold value, which is set as initial value of current monitoring;

if said initial value reaching setting threshold value, said initial value being flagged and saved, the upper limit or lower limit of threshold value be automatically reset;

the initial data being utilized as the initial value of current monitoring to launch the analysis and computation for the monitoring;

when monitoring value reaching to said reset limits of threshold value, abnormal electrophysiological event being flagged and transmitted;

if said initial data exceeding said setting range of threshold value, the abnormal electrophysiological event being flagged and transmitted;

step2;

different levels of warning being set and represented by different flags based on the different electrophysiological abnormal signals;

forewarning privileges of said remote mobile monitoring device being set as first-level warning privilege, second-level warning privilege and third-level warning privilege;

said mechanical vibration buzzer circuit being used for the operation of alarming or forewarning when warning flag being received;

step3;

retrieving the monitoring data being saved prior to the abnormal electrophysiological event occurred;

an event data package being created by six event data related to current monitoring event in sixty-minute interval and corresponded time when the event data being saved;

the maximum event data being retrieved if the saved intervals being less than six;

step4;

when warning flag being detected, said wireless network interface circuit to initiate said short-range communication protocol to send searching command;

after exterior network terminal interface being responded in a valid distance, said wireless network interface circuit transmitting an individual identity address code Pin for pairing, then wireless dual-direction digital communication being linked;

a recognition command be sent to determine whether said exterior network being either a mobile Internet or cable network;

step5;

if the exterior network being detected as mobile Internet, the permanent IP address of remote electrophysiological data monitoring server being read, and TCP/IP protocol and PPP protocol being performed;

if the exterior network being detected as a cable network, the permanent IP address of remote electrophysiological data monitoring server being read, the cable network control command being trigged to control said wireless network interface circuit to connect the mobile Internet and cable network, to perform said digital communication of network with said remote electrophysiological data monitoring server, to transmit said event data packages or data information, to receive control command, to analyze results, to process notes sent from doctors, and to execute the control command;

step6;

said wireless network interface circuit being commanded by said software application to enter into the online connection holding state (Hold), to cease data transmission and to hold online connection;

the digital communication of network being able be recovered immediately once activation signal being sent by said remote electrophysiological data monitoring server;

step7;

the operation of reading, writing, modification and deletion of data is performed in the corresponding areas of said data memory circuit;

the cyclic record in safety information storage area being unable to be deleted and the cyclic record period is reset;

step8;

when the setting information data being received from said remote mobile monitoring devices, writing commands being sent to the data memory circuit, the setting information data being saved in addressed in the setting information storage area;

step9;

when operating information data being received from said remote mobile monitoring devices, said software application sending writing commands to said data memory circuit, said operating information data being saved in addressed in the safety information storage area;

step10;

when the emergent calling signal be triggered, the emergent calling being flagged and transmitted, said software application is read SP code digital mobile phone number or Multimedia Messaging Service (MMS) address and helping information, to control said wireless network interface circuit to connect Short Message Service Center (SMSC) of mobile network terminal interface and to send helping information to the desired receiving ends;

if said software application not receiving “

received”

information being sent from the desired receiving ends in ten seconds, said software application to read permanent IP address and helping information of binding remote electrophysiological data monitoring server, to command said wireless network interface circuit to access WAN, to send helping information to said remote electrophysiological data monitoring server;

when said software application receiving “

received”

information being sent from said desired receiving ends, and the cyclic calling being terminated.

7. The WAN-based remote mobile monitoring method for electrophysiological data according to claim 6, wherein said remote mobile monitoring device is able to access WAN wirelessly, to enter into online connection holding state (Hold) under control of said software application, to terminate data transmission and hold online connection;

said digital communication of network is recovered immediately once said software application or said remote electrophysiological data monitoring server issuing activation signal.

8. The WAN-based remote mobile monitoring method for electrophysiological data according to claim 6, wherein said remote mobile monitoring device is able to access said wireless network interface circuit, to connect said SMSC under control of said software application, to transmit helping information to the desired receiving ends via SMS or MMS and is receive information being sent from the desired receiving ends.

9. The WAN-based remote mobile monitoring method for electrophysiological data according to claim 6, wherein said wireless network interface circuit is able to receive the control command which is be able to being standard operating command and data, or user-defined command and data including requesting password command, function setting command, internal information command and warning command of abnormal pathological event.

10. The WAN-based remote mobile monitoring method for electrophysiological data according to claim 6, wherein said setting information is able to be texts, symbols, characters, digitals, images and mixed objects, and to be permanent IP address, SP code, digital mobile phone number, MMS address, username and password and helping information of said binding remote electrophysiological data monitoring server.

11. The WAN-based remote mobile monitoring method for electrophysiological data according to claim 6, wherein said operating information data including on-off times and time, warning contents and time, manner of sending data and time, control command data content and time, receiving medical advice content and time, emergent calling triggering event and time, and responding/answering and time.