Device and method for producing spherical segmented flow

• US 8,114,319 B2
• Filed: 12/19/2005
• Issued: 02/14/2012
• Est. Priority Date: 02/04/2005
• Status: Active Grant

• Current Assignee: Q Chip Ltd.
• Original Assignee: Q Chip Ltd.
• Inventors: Davis, Robert Huw, Palmer, Daniel David
• Primary Examiner(s): THEISEN, MARY LYNN F
• Application Number:
  US11/883,611
• Publication Number:
  US 20080314464A1
• Time in Patent Office: 2,248 Days
• Field of Search: None
• US Class Current: 264/11
• CPC Class Codes: B01F 25/433 Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
• CPC Class Codes: B01F 25/4331 Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
• CPC Class Codes: B01F 25/4336 Mixers with a diverging cross-section
• CPC Class Codes: B01F 33/3011 using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
• CPC Class Codes: B01J 19/0093 Microreactors, e.g. miniaturised or microfabricated reactors laboratory containers with capillary fluid transport in microfabricated channels or chambers B01L3/5027
• CPC Class Codes: B01J 2219/00783 Laminate assemblies, i.e. the reactor comprising a stack of plates
• CPC Class Codes: B01J 2219/00837 comprising coatings other than catalytically active coatings
• CPC Class Codes: B01J 2219/0086 Dimensions of the flow channels
• CPC Class Codes: B01J 2219/00889 Mixing
• CPC Class Codes: B01J 2219/00936 UV-radiations
• CPC Class Codes: Y10T 137/2076 Utilizing diverse fluids

Abstract

The invention provides a device (1, 301, 501) for producing a spherical segmented flow of fluid, which device includes: a functional fluid conduit (6, 506) arranged to contain a functional fluid (15, 515); at least two carrier fluid conduits (7, 8, 507, 508), each carrier fluid conduit arranged to carry a carrier fluid (16, 514), the functional fluid conduit merging with the carrier fluid conduits at a junction (9) to form an encased flow conduit (9a, 529) thereby permitting functional fluid to be sandwiched (or encased) by the carrier fluid to form an encased flow, the encased flow conduit having a discontinuity (10, 510) therein such that the encased flow forms into a flow of alternate segmented spheres after the discontinuity, wherein the device is provided with a segmented flow conduit (11, 511) downstream of the encased flow conduit, the encased segmented flow conduit being provided with an enlargement (21, 512) in cross-section.

Claims

1. A device for producing a spherical segmented flow of fluid, which device includes:

a functional fluid conduit arranged to contain a functional fluid;

at least two carrier fluid conduits, each carrier fluid conduit arranged to carry a carrier fluid, the functional fluid conduit merging with the carrier fluid conduits at a junction to form an encased flow conduit thereby permitting functional fluid to be sandwiched (or encased) by the carrier fluid to form an encased flow, the encased flow conduit having a discontinuity therein such that the encased flow forms into a flow of alternate segmented spheres after the discontinuity, wherein the device is provided with a segmented flow conduit downstream of the encased flow conduit, the segmented flow conduit being provided with an enlargement in cross-section and a step coincident with the enlargement in cross-section the depth of the segmented flow conduit immediately downstream of the step being defined as 2a, and the step being provided at a distance of up to 5a downstream of the discontinuity.

2. A device according to claim 1 wherein the enlargement in cross-section is substantially at or immediately downstream of the discontinuity.

3. A device according to claim 1 wherein the enlargement is sufficiently close to the discontinuity so as to encourage the formation of spherical segments.

4. A device according to claim 1 wherein the discontinuity is in the form of a constriction.

5. A device according to claim 1 wherein the encased flow conduit and the segmented flow conduit are provided by a unitary conduit.

6. A device according to claim 1, wherein if the depth of the encased flow conduit or segmented flow conduit immediately downstream of the enlargement is, 2 a, then the enlargement is provided a distance of from 0.5 a to 1.5 a downstream of the discontinuity.

7. A device according to claim 1 wherein if the cross-sectional area of the encased flow conduit or segmented flow conduit immediately downstream of the enlargement is 4 a², then the enlargement is provided a distance of from 0.5 a to 1.5 a downstream of the discontinuity.

8. A device according to claim 1 wherein if the width of the encased flow conduit or segmented flow conduit immediately downstream of the enlargement is 2 a, then the enlargement is provided a distance of from 0.5 a to 1.5 a downstream of the discontinuity.

9. A device according to claim 1 wherein the cross-sectional area of the encased flow conduit or segmented flow conduit immediately downstream of the enlargement is from 3.5 to 4.5 times larger than the cross-sectional area of the encased flow conduit or segmented flow conduit immediately upstream of the enlargement.

10. A device according to claim 1 wherein two or more feeder conduits merge to form the functional fluid conduit.

11. A device according to claim 1 wherein the functional fluid conduit is shaped and dimensioned to permit mixing of fluid contained therein.

12. A device according to claim 1 comprising a segmented flow conduit wherein a portion of the segmented flow conduit provides an irradiation zone, the device further comprising an external radiation source arranged, in use, to illuminate the irradiation zone.

17. A device according to claim 1, wherein the step is provided a distance of from 0.5 a to 3 a downstream of the discontinuity.

18. A device according to claim 1 wherein the step is provided a distance from 0.5 a to 1.5 a downstream of the discontinuity.

13. A microfluidic device, having

a functional conduit for carrying a functional fluid, first and second lateral carrier fluid conduits confluent with the functional conduit at a junction region, for carrying a carrier fluid,

wherein the device is provided with a further conduit extending from the junction region,

the device being provided with a constriction or another discontinuity for producing a flow of spherical segments of functional fluid dispersed in the carrier fluid, the constriction or other discontinuity being located substantially at or downstream of the junction,

the further conduit being provided with an enlargement in cross-section substantially at or downstream of the constriction or other discontinuity and a step coincident with the enlargement in cross-section, the depth of the further conduit immediately downstream of the step being defined as 2 a, and the step being provided at a distance of up to 5 a downstream of the discontinuity.

14. A device according to claim 13 wherein the encased flow conduit is provided with an enlargement in cross-section substantially at or immediately downstream of the constriction or other discontinuity.

15. A device according to claim 13 wherein the enlargement in cross-section is sufficiently close to the constriction or other discontinuity so as to encourage formation of spherical segments.

16. A method of producing a spherical segmented flow of a fluid, which method includes:

introducing a functional fluid into a functional fluid conduit and a carrier fluid into a carrier fluid conduit;

permitting the carrier fluid to contact the functional fluid such that the carrier fluid encases or sandwiches the functional fluid;

providing a discontinuity in the flow of the sandwiched or encased flow such that as the encased flow passes the discontinuity, a vena contracta effect is achieved thereby forcing the encased flow to form into spherical segments,

the method further comprising providing an enlargement in cross-section in a conduit substantially at or immediately downstream of the discontinuity, or sufficiently close to the discontinuity so as to encourage the formation of spherical segments, and a step coincident with the enlargement in cross-section the depth of the further conduit immediately downstream of the step being defined as 2 a, and the step being provided at a distance of up to 5 a downstream of the discontinuity.