RGD peptide attached to bioabsorbable stents
First Claim
1. A method of forming a medical device comprising a chemo-attractant attached to a surface layer of polymer on the medical device, comprisingproviding a spacer compound comprising a hydrophobic moiety and a hydrophilic moiety,grafting or embedding the spacer compound to the surface layer of the polymer to cause the hydrophobic moiety to be grafted to or embedded within the surface layer of polymer such that the hydrophilic moiety of the spacer compound projects from the surface layer of polymer, andattaching a chemo-attractant to the hydrophilic moiety.
1 Assignment
0 Petitions
Accused Products
Abstract
Provided herein is a method of forming medical device that includes RGD attached to the device via a spacer compound. The method comprises providing a spacer compound comprising a hydrophobic moiety and a hydrophilic moiety, grafting or embedding the spacer compound to the surface layer of the polymer to cause the hydrophobic moiety to be grafted to or embedded within the surface layer of polymer, and attaching a chemo-attractant to the hydrophilic moiety.
-
Citations
28 Claims
-
1. A method of forming a medical device comprising a chemo-attractant attached to a surface layer of polymer on the medical device, comprising
providing a spacer compound comprising a hydrophobic moiety and a hydrophilic moiety, grafting or embedding the spacer compound to the surface layer of the polymer to cause the hydrophobic moiety to be grafted to or embedded within the surface layer of polymer such that the hydrophilic moiety of the spacer compound projects from the surface layer of polymer, and attaching a chemo-attractant to the hydrophilic moiety.
Specification