Apparatus and methods for aspirating emboli

• US 8,123,777 B2
• Filed: 09/30/2005
• Issued: 02/28/2012
• Est. Priority Date: 07/24/2001
• Status: Expired due to Fees

• Current Assignee: Incept LLC
• Original Assignee: Incept LLC
• Inventors: Krolik, Jeffrey, Salahieh, Amr
• Primary Examiner(s): Nguyen, Tuan
• Application Number:
  US11/241,029
• Publication Number:
  US 20060025806A1
• Time in Patent Office: 2,342 Days
• Field of Search: 606/159, 606/170, 606/194, 606/200, 606/192, 604/96, 604/7, 604/22, 604/101, 604/19, 604/171, 604/264, 604/280
• US Class Current: 606/200
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2/0105 Open ended, i.e. legs gathered only at one side

Abstract

Apparatus and methods for aspirating emboli from a vascular filter or stent within a patient'"'"'s circulatory system are provided. A filter sac of the vascular filter permits blood flow and captures emboli from the flow. The aspiration device removes emboli from within or proximal to the vascular filter or stent to reduce the risk to the ischemia during retrieval of the vascular filter and during a treatment procedure. Retrieval of the vascular filter may be accomplished using either the aspiration catheter or a separate retrieval catheter.

Claims

1. Apparatus for filtering and aspirating emboli from a vessel comprising:

a guidewire;

a vascular filter mounted on the guidewire, the vascular filter including a blood-permeable element, the vascular filter causing emboli to become deposited in the vessel in the vicinity of the vascular filter; and

a first catheter having proximal and distal ends, proximal and distal openings, and a lumen defined by a catheter wall extending between the proximal and distal openings, the distal end of the first catheter has a rounded end with the distal opening off-center such that, when viewed in a cross-section that extends along a central longitudinal axis of the lumen, the catheter wall extends in a generally straight fashion towards the proximal end from the distal opening on a first side and, on a second side opposite the first side, has a first portion nearest the distal opening that is curved in a concave fashion towards the lumen and a second portion extending proximally from the first portion in a generally straight fashion towards the proximal end;

wherein the guidewire passes through the distal opening, is at least partially disposed within the lumen, and passes through a port disposed in the catheter wall proximal of the distal end and distal of the proximal end;

wherein the first catheter is adapted to be advanced along the guidewire to a location in the vessel in the vicinity of the vascular filter to aspirate emboli;

wherein the concave curve of the first portion at least partially defines the distal opening.

2. The apparatus of claim 1, wherein the distal end of the first catheter is dimensioned to permit the distal opening to enter the blood-permeable element.

3. The apparatus of claim 1, wherein the distal end of the first catheter includes one or more aspiration holes disposed proximal of the distal opening.

4. The apparatus of claim 1, wherein the first catheter comprises a rapid exchange device.

5. The apparatus of claim 1, further comprising a second catheter having proximal and distal ends, proximal and distal openings, and a lumen extending between the proximal and distal openings, the lumen of the second catheter dimensioned to accept the first catheter therein.

6. The apparatus of claim 5, wherein the first catheter includes one or more aspiration holes disposed proximal of the distal opening and the second catheter selectively occludes the one or more aspiration holes.

7. The apparatus of claim 5, wherein the distal opening of the second catheter is dimensioned so that the vascular filter may be at least partially retracted in the lumen of the second catheter.

8. Apparatus for filtering and aspirating emboli from a vessel comprising:

a guidewire;

a vascular filter mounted on the guidewire, the vascular filter including a blood-permeable element, the vascular filter causing emboli to become deposited in the vessel in the vicinity of the vascular filter; and

a first catheter having proximal and distal ends, proximal and distal openings, and a lumen defined by a catheter wall extending between the proximal and distal openings, the distal end of the first catheter has a rounded end with the distal opening off-center such that, when viewed in a cross-section that extends along a central longitudinal axis of the lumen, the catheter wall extends in a generally straight fashion towards the proximal end from the distal opening on a first side and, on a second side opposite the first side, has a first portion nearest the distal opening that is curved in a concave fashion towards the lumen and a second portion extending proximally from the first portion in a generally straight fashion towards the proximal end;

wherein the guidewire passes through the distal opening, is at least partially disposed within the lumen, and passes through a port disposed in the catheter wall proximal of the distal end and distal of the proximal end;

wherein the first catheter is adapted to be advanced along the guidewire to a location in the vessel in the vicinity of the vascular filter to aspirate emboli;

wherein the concave curve of the first portion at least partially defines the distal opening;

wherein the distal opening of the first catheter is adapted to accommodate at least a portion of the vascular filter within the lumen of the first catheter.

9. The apparatus of claim 8, wherein the distal end of the first catheter is dimensioned to permit the distal opening to enter the blood-permeable element.

10. The apparatus of claim 8, wherein the distal end of the first catheter includes one or more aspiration holes disposed proximal of the distal opening.

11. The apparatus of claim 8, wherein the first catheter comprises a rapid exchange device.

12. The apparatus of claim 8, further comprising a second catheter having proximal and distal ends, proximal and distal openings, and a lumen extending between the proximal and distal openings, the lumen of the second catheter dimensioned to accept the first catheter therein.

13. The apparatus of claim 12, wherein the first catheter includes one or more aspiration holes disposed proximal of the distal opening and the second catheter selectively occludes the one or more aspiration holes.

14. The apparatus of claim 12, wherein the distal opening of the second catheter is dimensioned so that the vascular filter may be at least partially retracted in the lumen of the second catheter.