Negative ion beam source vacuum method and apparatus used in conjunction with a charged particle cancer therapy system

• US 8,129,694 B2
• Filed: 10/01/2009
• Issued: 03/06/2012
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: Andrey Vladimirovich Balakin, Pavel Vladimirovich Balakin
• Original Assignee: Vladimir Balakin
• Inventors: Balakin, Vladimir
• Primary Examiner(s): Maskell, Michael
• Application Number:
  US12/571,589
• Publication Number:
  US 20100014640A1
• Time in Patent Office: 887 Days
• Field of Search: 250/396.R, 250/492.1, 250/492.3, 313/62, 315/503, 315/504
• US Class Current: 250/396.R
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: H01J 27/028 Negative ion sources
• CPC Class Codes: H01J 3/04 Ion guns
• CPC Class Codes: H05H 13/04 Synchrotrons
• CPC Class Codes: H05H 7/04 Magnet systems , e.g. undulators, wigglers free-electron laser H01S3/0903; Energisation thereof

Abstract

The invention comprises a negative ion beam source vacuum method and apparatus used as part of an ion beam injection system, which is used in conjunction with multi-axis charged particle or proton beam radiation therapy of cancerous tumors. The negative ion beam source contains a vacuum chamber isolated by a vacuum barrier from the vacuum tube of the synchrotron. The negative ion beam source vacuum system preferably includes: a first pump turbo molecular pump, a large holding volume, and a semi-continuously operating pump. By only pumping ion beam source vacuum chamber and by only semi-continuously operating the ion beam source vacuum based on sensor readings about the holding volume, the lifetime of the semi-continuously operating pump is extended.

Claims

1. An apparatus for converting a charged particle stream into a charged particle beam used in a cancer therapy system, said apparatus comprising:

a negative ion source configured to produce the charged particle stream in a first partial vacuum section; and

a converting foil configured to convert the charged particle stream into the charged particle beam, the charged particle beam comprising an oppositely signed charge from the charged particle stream,

wherein said converting foil provides a portion of a vacuum barrier between said first partial vacuum section and a second partial vacuum section in a synchrotron, and

wherein a first pump system operates to maintain a first partial vacuum in said first partial vacuum section.

2. The apparatus of claim 1, wherein said first pump system further comprises:

a continuously operating turbo molecular pump configured to pump gas molecules in said first partial vacuum section to a holding volume;

a pressure sensor configured to monitor pressure in said holding volume; and

a pump controller configured to, based on readings from said pressure sensor, control a semi-continuously operating pump removing contents from said holding volume to atmosphere.

3. The apparatus of claim 2, further comprising:

a second pump system configured to hold a vacuum in said second partial vacuum section, wherein pressure in said first partial vacuum section comprises a pressure of less than about 0.0001 torr and more than about 0.000001 torr, wherein pressure in said second partial vacuum system comprises a lower pressure of less than about 0.000001 torr, wherein said second pump system maintains a lower pressure in said second partial vacuum section compared to said first partial vacuum section as a result of said vacuum barrier, wherein efficiency of cycling the charged particle beam in said synchrotron increases due to said lower pressure in said synchrotron.

4. The apparatus of claim 2, wherein said converting foil comprises:

a beryllium carbon film, wherein said film comprises a thickness of about thirty to two hundred micrometers.

5. The apparatus of claim 1, further comprising:

an ion beam focusing lens, wherein said lens comprises electric field lines running in said first partial vacuum section through the charged particle stream, wherein the electric field lines focus the charged particle stream, said ion beam focusing lens further comprising;

a first focusing electrode circumferentially surrounding a first portion of the charged particle stream;

a second focusing electrode comprising metal conductive paths at least partially blocking the charged particle stream,

wherein said first focusing electrode and said second focusing electrode comprises opposite charge,

wherein first electric field lines run between said first focusing electrode and said second focusing electrode, and

wherein the charged particle stream encounters first force vectors running up the first electric field lines that focus the charged particle stream.

6. The apparatus of claim 5, said ion beam focusing lens further comprising:

at least two additional oppositely charged focusing electrodes circumferentially surrounding a second portion of the charged particle stream,

wherein second electric field lines run between said at least two additional electrodes,

wherein the charged particle stream encounters second force vectors running up the second electric field lines that focus the charged particle stream.

7. The apparatus of claim 2, wherein said negative ion source comprises:

a magnetic material producing a magnetic field loop,

wherein the magnetic field loop yields a magnetic barrier between a high temperature plasma chamber and a low temperature plasma region,

wherein said magnetic barrier selectively passes elements of plasma in said high temperature plasma chamber to said low temperature plasma region,

wherein low energy electrons interact with atomic hydrogen to create hydrogen anions in said low temperature plasma region;

wherein application of a high voltage pulse extracts negative ions from said negative ion source to form the charged particle stream.

8. The apparatus of claim 1, wherein said synchrotron further comprises:

an extraction material;

at least a one kilovolt direct current field applied across a pair of extraction blades; and

a deflector,

wherein the charged particle beam passes through said extraction material resulting in a reduced energy charged particle beam,

wherein the reduced energy charged particle beam passes between said pair of extraction blades, and

wherein the direct current field redirects the reduced energy charged particle beam out of said synchrotron through said deflector,

wherein said deflector yields an extracted charged particle beam.

9. The apparatus of claim 8, further comprising:

an X-ray source located within about forty millimeters of the extracted charged particle beam, wherein said X-ray source maintains a single position both during use of said X-ray source and during proton therapy with said cancer therapy system.

10. The apparatus of claim 8, wherein said cancer therapy system further comprises:

a rotatable platform configured to rotate during an irradiation period;

an immobilization system mounted on said rotatable platform, wherein said immobilization system restricts tumor motion during delivery of the extracted charged particle beam,

wherein said rotatable platform rotates to at least ten irradiation positions in less than five minutes during tumor irradiation with the extracted charged particle beam.

11. A method for converting a charged particle stream into a charged particle beam used in a cancer therapy system, said method comprising the steps of:

generating the charged particle stream in a first partial vacuum section using a negative ion source;

converting the charged particle stream into an oppositely charged particle beam with a converting foil; and

maintaining a first partial vacuum in said first partial vacuum section with a first pump system,

wherein said converting foil provides a portion of a vacuum barrier between said first partial vacuum section and a second partial vacuum section in a synchrotron used in said cancer therapy system.

12. The method of claim 11, further comprising the steps of:

continuously operating a turbo molecular pump in said first pump system to pump gas molecules in said first partial vacuum section to a holding volume;

monitoring pressure in said holding volume with a pressure sensor; and

based on readings from said pressure sensor, semi-continuously operating a second pump to remove contents from said holding volume to atmosphere.

13. The apparatus of claim 12, further comprising the step of:

maintaining a vacuum in said second partial vacuum section with a second pump system, wherein pressure in said first partial vacuum section comprises a pressure of less than about 0.0001 torr and more than about 0.000001 torr, wherein pressure in said second partial vacuum system comprises a lower pressure of less than about 0.000001 torr, wherein said second pump system maintains a lower pressure in said second partial vacuum section compared to said first partial vacuum section as a result of said vacuum barrier, wherein efficiency of cycling the charged particle beam in said synchrotron increases due to said lower pressure in said synchrotron.

14. The method of claim 11, further comprising the steps of:

producing a magnetic field loop with a magnetic material at least partially located inside said negative ion source, wherein said magnetic field loop yields a magnetic barrier between a high temperature plasma chamber and a low temperature plasma region, wherein said magnetic barrier selectively passes elements of plasma in said high temperature plasma chamber to said low temperature plasma region, wherein low energy electrons interact with atomic hydrogen to create hydrogen anions in said low temperature plasma region; and

applying a high voltage pulse across said low temperature plasma region to extract negative ions from said negative ion source to form the charged particle stream.

15. The method of claim 11, further comprising the steps of:

circumferentially surrounding a portion of the charged particle stream with a first focusing electrode;

providing a second focusing electrode, said second focusing electrode comprising metal conductive paths at least partially blocking the charged particle stream, wherein electric field lines run between said first focusing electrode and said second focusing electrode, and

focusing the charged particle stream when the charged particle stream encounters force vectors running along the electric field lines.

16. The method of claim 11, further comprising the steps of:

injecting the charged particle beam into said synchrotron;

accelerating the charged particle beam with said synchrotron; and

extracting the charged particle beam from said synchrotron, said step of extracting comprising the steps of;

transmitting the charged particle beam through an extraction material, said extraction material yielding a reduced energy charged particle beam;

applying an extraction field of at least five hundred volts across a pair of extraction blades; and

passing the reduced energy charged particle beam between said pair of extraction blades,

wherein said extraction field redirects the reduced energy charged particle as an energy controlled extracted charged particle beam.

17. The method of claim 16, further comprising the step of:

controlling intensity of the energy controlled extracted charged beam with an intensity controller, wherein said step of controlling comprises the steps of;

inputting a feedback signal to said intensity controller, said step of transmitting yielding emitted electrons in the process of the charged particle beam striking said extraction material, wherein the emitted electrons are converted to said feedback signal;

comparing said feedback signal to an irradiation plan intensity; and

adjusting oscillation of the charged particle beam with said intensity controller until said feedback signal yields intensity proximate an irradiation plan intensity,

wherein said energy controlled extracted charged particle beam comprises an independent intensity control, wherein said intensity comprises a number of protons traveling in said extracted charged particle beam per unit of time.

18. The method of claim 16, further comprising the step of:

generating a tumor X-ray image using an X-ray source located within less than about one hundred millimeters of the extracted charged particle beam, wherein said X-ray source maintains a static position during both;

use of said X-ray source; and

use of the extracted charged particle beam for tumor therapy.

19. The method of claim 16, further comprising the steps of:

rotating a rotatable platform of said irradiation device during an irradiation period;

providing an immobilization system mounted on said first rotatable platform, wherein said immobilization system restricts tumor motion during delivery of the extracted charged particle beam,

irradiating the tumor with said cancer therapy system, wherein said rotatable platform rotates to at least ten irradiation positions during said step of irradiating.

20. A method for converting a charged particle stream into a charged particle beam used in a cancer therapy system, said method comprising the steps of:

converting the charged particle stream into the charged particle beam with a converting foil, the converting foil comprising carbon, wherein the charged particle beam comprising an oppositely signed charge from the charged particle stream; and

maintaining a first partial vacuum in said first partial vacuum section with a first pump system,

wherein said converting foil provides a portion of a vacuum barrier between a source of the charged particles and a second partial vacuum section in a synchrotron.