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Baroreflex stimulation synchronized to circadian rhythm

  • US 8,131,373 B2
  • Filed: 03/30/2010
  • Issued: 03/06/2012
  • Est. Priority Date: 12/24/2003
  • Status: Expired due to Term
First Claim
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1. A method for operating an implantable medical device, comprising:

  • sensing and recording parameters related to hypertension;

    generating a patient-specific circadian rhythm template based on the recorded parameters;

    applying a baroreflex stimulation therapy at a stimulation intensity using a baroreflex stimulator in the implantable medical device; and

    modulating the baroreflex stimulation therapy based on the patient-specific circadian rhythm template stored within the implantable medical device, wherein modulating the baroreflex stimulation therapy includes using the patient specific circadian rhythm template to change the stimulation intensity to mimic natural blood pressure fluctuations during the day.

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