Method and device for image-based biological data quantification
First Claim
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1. A method for determining a concentration of a biological target, the method comprising:
- capturing an image of a ticket including the biological target;
extracting a region of interest from the captured image;
detecting a target from the extracted region of interest comprising a multi-level target detection based on a concentration of the target, the multi-level target detection including;
detecting a target with a high concentration by applying an edge detection and circular contour analysis to extract the target with a high concentration;
detecting a target with a medium concentration by analyzing a local grayscale distribution to separate a target area with circular shape background; and
detecting a target with a low concentration by extracting partial circular shape features from the background;
electronically computing intensity of the target in the region of interest; and
determining the concentration of the biological target according to the computed intensity.
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Abstract
A device and method for determining a concentration of a biological target including capturing an image of a ticket that contains the biological target; extracting a region of interest from the captured image; detecting a target from the extracted region of interest; computing intensity of the target in the region of interest; and determining the concentration of the biological target according to the computed intensity.
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Citations
20 Claims
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1. A method for determining a concentration of a biological target, the method comprising:
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capturing an image of a ticket including the biological target; extracting a region of interest from the captured image; detecting a target from the extracted region of interest comprising a multi-level target detection based on a concentration of the target, the multi-level target detection including; detecting a target with a high concentration by applying an edge detection and circular contour analysis to extract the target with a high concentration; detecting a target with a medium concentration by analyzing a local grayscale distribution to separate a target area with circular shape background; and detecting a target with a low concentration by extracting partial circular shape features from the background; electronically computing intensity of the target in the region of interest; and determining the concentration of the biological target according to the computed intensity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 14)
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8. A portable device for determining a concentration of a biological target comprising:
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an optical module for capturing an image of a ticket including the biological target; a sensor for converting the captured image to digital data; and a processor for processing the digital data, the processor comprising; an image calibration module for checking the ticket validity from the captured image, a target detection module for detecting a target from the extracted region of interest using a multi-level target detection based on a concentration of the target, wherein the target detection module is configured for; detecting a target with a high concentration by applying an edge detection and circular contour analysis to extract the target with a high concentration; detecting a target with a medium concentration by analyzing a local grayscale distribution to separate a target area with circular shape background; and detecting a target with a low concentration by extracting partial circular shape features from the background, and a target quantification module for computing intensity of the target in the region of interest and determining the concentration of the biological target according to the computed intensity. - View Dependent Claims (9, 10, 11, 12, 13)
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15. A device for determining a concentration of a biological target comprising:
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means for capturing an image of a ticket including the biological target; means for extracting a region of interest from the captured image; means for detecting a target from the extracted region of interest comprising a multi-level target detection based on a concentration of the target, the multi-level target detection including; means for detecting a target with a high concentration by applying an edge detection and circular contour analysis to extract the target with a high concentration means for detecting a target with a medium concentration by analyzing a local grayscale distribution to separate a target area with circular shape background; and means for detecting a target with a low concentration by extracting partial circular shape features from the background; means for computing intensity of the target in the region of interest; and means for determining the concentration of the biological target according to the computed intensity. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification