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Method and device for image-based biological data quantification

  • US 8,131,477 B2
  • Filed: 08/08/2006
  • Issued: 03/06/2012
  • Est. Priority Date: 11/16/2005
  • Status: Active Grant
First Claim
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1. A method for determining a concentration of a biological target, the method comprising:

  • capturing an image of a ticket including the biological target;

    extracting a region of interest from the captured image;

    detecting a target from the extracted region of interest comprising a multi-level target detection based on a concentration of the target, the multi-level target detection including;

    detecting a target with a high concentration by applying an edge detection and circular contour analysis to extract the target with a high concentration;

    detecting a target with a medium concentration by analyzing a local grayscale distribution to separate a target area with circular shape background; and

    detecting a target with a low concentration by extracting partial circular shape features from the background;

    electronically computing intensity of the target in the region of interest; and

    determining the concentration of the biological target according to the computed intensity.

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