Stent/fiber structural combinations

• US 8,133,268 B2
• Filed: 05/30/2007
• Issued: 03/13/2012
• Est. Priority Date: 05/30/2007
• Status: Active Grant

• Current Assignee: Cardinal Health Switzerland 515 GmbH (Cardinal Health, Inc.)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Bonsignore, Craig
• Primary Examiner(s): Severson, Ryan
• Assistant Examiner(s): MILES, JONATHAN WADE
• Application Number:
  US11/755,171
• Publication Number:
  US 20080300668A1
• Time in Patent Office: 1,749 Days
• Field of Search: 623/1.15, 623/1.16, 623/1.17, 623/1.18, 623/1.2, 623/23.7, 623/1.13, 623/1.38, 623/1.47, 623/1.54
• US Class Current: 623/1.16
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2002/9511 the retaining means being filaments or wires
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2230/0054 V-shaped

Abstract

A plurality of endoluminal segments axially connected by fiber bridges is disclosed. The endoluminal segments may either be balloon-expandable or self-expanding, with the preferred embodiment being superelastic nitinol. The intraluminal segments may possess a textured surface or at least one geometric feature per segment, preferably located at the apex of a strut pair comprising the intraluminal segment, preferably capable of serving as an anchoring point for the fiber bridges. These geometric features may transmit axially compressive loads during deployment from a device such as a catheter, and may further be capable of interlocking the endoluminal segments when constrained within a device such as a catheter. The fibers comprising the bridges may be polymeric, silk, collagen, bioabsorbable, or a blend thereof. The fiber network comprising the bridges may be regularly oriented, randomly oriented, localized, or continuous. Moreover, the intraluminal segments and fiber bridges may be individually impregnated with therapeutic material, or may both be impregnated with therapeutic material.

Claims

1. An implantable intraluminal medical scaffold comprising:

a substantially tubular structure having first and second open ends for fluid flow therethrough and configured to maintain luminal patency of a vessel, including two or more radially expandable stent segments wherein the two or more expandable stent segments are positioned axially adjacent to each other, each of the stent segments being formed from a plurality of strut pairs;

at least one notched tab structure located at an apex of at least one strut pair on each of the stent segments, the at least one notched tab structure having a first flat bearing surface, and

a second flat bearing surface formed on at least two strut pairs positioned opposite the at least one notched tab on adjacent stent segments, the first flat bearing surfaces and the second flat bearing surfaces being configured to transmit compressive loads between the stent segments during deployment and

one or more substantially axially oriented flexible fiber bridges interconnecting the adjacent two or more radially expandable stent segments to form the substantially tubular structure, the flexible fiber bridges being configured for attachment of the two or more radially expandable stent segments and arranged such that they offer substantially no impedance to fluid flow through the tubular structure, the flexible fiber bridges being anchored by a knotted loop on the at least one notched tab structure on each of the stent segments, the notched tabs being configured to hold the flexible fiber bridges.

2. The implantable intraluminal medical scaffold according to claim 1, wherein the at least one or more radially expandable stent segments comprise a balloon-expandable material.

3. The implantable intraluminal medical scaffold according to claim 2, wherein the balloon-expandable material comprises stainless steel.

4. The implantable intraluminal medical scaffold according to claim 2, wherein the balloon-expandable material comprises a cobalt-chromium alloy.

5. The implantable intraluminal medical scaffold according to claim 1, wherein the at least one or more radially expandable stent segments comprise a self-expanding material.

6. The implantable intraluminal medical scaffold according to claim 5, wherein the self-expanding material comprise a nickel-titanium alloy.

7. The implantable intraluminal medical scaffold according to claim 1, wherein the one or more flexible fiber bridges comprise individual filaments.

8. The implantable intraluminal medical scaffold according to claim 1, wherein the one or more flexible fiber bridges comprise fiber networks.

9. The implantable intraluminal medical scaffold according to claim 1, wherein the flexible fiber bridges comprise polymeric materials.

10. The implantable intraluminal medical scaffold according to claim 1, wherein the flexible fiber bridges comprise silk.

11. The implantable intraluminal medical scaffold according to claim 1, wherein the flexible fiber bridges comprise collagen.

12. The implantable intraluminal medical scaffold according to claim 1, wherein the flexible fiber bridges comprises bioabsorbable materials.

13. The implantable intraluminal medical scaffold according to claim 1, wherein the flexible fiber bridges comprise non-bioabsorbable materials.

14. The implantable intraluminal medical scaffold according to claim 1, wherein the two or more radially expandable stent segments comprise a textured surface.

15. The implantable intraluminal medical scaffold according to claim 1, wherein at least one of the two or more radially expandable stent segments and the one or more flexible fiber bridges comprise a therapeutic agent affixed thereto.

16. The implantable intraluminal medical scaffold according to claim 1, wherein at least one of the two or more radially expandable stent segments and the one or more flexible fiber bridges comprise a therapeutic agent incorporated therein.

17. The implantable intraluminal medical scaffold according to claim 1, wherein the one or more flexible fiber bridges form an interwoven network.