Brachytherapy apparatus

• US 8,137,256 B2
• Filed: 12/16/2005
• Issued: 03/20/2012
• Est. Priority Date: 12/16/2005
• Status: Expired due to Fees

• Current Assignee: Portola Medical, Inc. (Huiheng Medical, Inc.)
• Original Assignee: Portola Medical, Inc. (Huiheng Medical, Inc.)
• Inventors: Cutrer, L. Michael, Terwilliger, Richard A., Winch, Fredrick, Zhang, John, Higgins, Wayne, Ellard, Terence, Bossi, David
• Primary Examiner(s): GILBERT, SAMUEL G
• Application Number:
  US11/305,437
• Publication Number:
  US 20070142694A1
• Time in Patent Office: 2,286 Days
• Field of Search: 600 1- 8, 128/898, 128/899
• US Class Current: 600/3
• CPC Class Codes: A61N 2005/1018 with multiple channels for guiding radioactive sources
• CPC Class Codes: A61N 5/1015 Treatment of resected cavities created by surgery, e.g. lumpectomy

Abstract

The present disclosure provides a brachytherapy apparatus that delivers a low dose, partial breast irradiation treatment for post-lumpectomy patients via introduction of a catheter-like device through a cannula. The apparatus may be introduced post-surgically with local anesthesia under image guidance into the previous excision site and into a cavity by a surgeon. The brachytherapy apparatus includes a seed containment device configured to contain a plurality of low-dose radioactive seeds therein. The seed containment device may be one or more thin-walled tubes. The apparatus is further configured to expand so that at least a portion of the seed containment device is positioned against the remaining tissue and the plurality of radioactive seeds are disposed at the perimeter of the seed containment device. Also described are various clamps for the apparatus, and sleeves for adjusting the size of the device to fit a cavity when the apparatus is in use.

Claims

1. A method for delivering localized irradiation to tissue near a cavity that lies beneath a surface of a body with a brachytherapy apparatus that includes a plurality of tubes configured to controllably move from a collapsed state to an expanded state while within the cavity, the method comprising in the order recited:

inserting the tubes while in the collapsed state into the cavity such that a first portion of the tubes lies within the cavity and a second portion of the tubes lies outside of the body;

expanding the first portion of the tubes from the collapsed state to the expanded state while the first portion of the tubes remains within the cavity;

cutting the tubes at a location on the tubes that is just outside of the body, thereby removing the portion of the tubes from the brachytherapy apparatus; and

inserting one or more radioactive seeds into one or more of the tubes.

2. The method of claim 1 wherein the body is a breast and the cavity is within the breast.

3. The method of claim 2 wherein the brachytherapy apparatus includes a member that is configured to be sutured to the surface of the breast, the method further comprising suturing the member to the surface of the breast.

4. The method of claim 1 further comprising clamping the tubes while in the expanded state to prevent the tubes from returning to the collapsed state.

5. The method of claim 1 further comprising covering the cut end of the tubes.

6. The method of claim 5 wherein the covering the cut end of the tubes includes placing a removable cap over the cut end of the tubes.

7. A method for delivering localized irradiation to tissue near a cavity that lies beneath a surface of the body with a brachytherapy apparatus that includes a plurality of tubes configured to controllably move from a collapsed state to an expanded state while within the cavity, the method comprising:

while the tubes are in the collapsed state, sliding a sleeve surrounding a first length of the tubes to adjust the length of a second length of the tubes that is not surrounded by the sleeve so as to cause the second length of the tubes, when later expand, to be substantially the size of the cavity, the second length of tubes remaining collapse during the sliding of the sleeve;

inserting the tubes while in the collapsed state into the cavity such that the second length of the tubes lies substantially within the cavity;

expanding the second length of the tubes while within the cavity without also expanding the first length of tubes and without sliding the sleeve; and

inserting one or more radioactive seeds into one or more of the tubes.

8. The method of claim 7 wherein the body is a breast and the cavity is within the breast.

9. The method of claim 7 further comprising clamping the tubes while in the expanded state to prevent the tubes from returning to the collapsed state.

10. The method of claim 7 further comprising cutting the tubes after the tubes are positioned within the cavity and expanded at a location on the tubes that is near flush with and just outside of the body, thereby removing a portion of the tubes from the brachytherapy apparatus.