Medical device for detecting ischemia and a method for such a device
First Claim
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1. An implantable medical device comprising:
- a pulse generator that emits cardiac stimulation pulses;
at least one medical lead connected to said pulse generator that delivers said stimulating pulses in vivo to cardiac tissue of a heart of a patient;
an impedance measuring circuit that, during impedance measurement sessions, generates electrical signals applied between at least a first electrode and a second electrode, among electrodes carried by said at least one medical lead, in at least two electrode configurations according to a predetermined scheme, and that measures impedance in the tissue between said first electrode and said second electrode of each of said at least two electrode configurations; and
an ischemia detector that evaluates the measured impedances by comparing the measured impedances with at least one reference impedance image of the heart comprising a plurality of impedance regions, to detect changes in the measured impedances that are consistent with ischemia, and that determines a location of said ischemia with respect to at least one of said regions.
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Abstract
In a method and medical device for detecting an ischemic episode and to determine a location of ischemia in a heart of a patient, an impedance measuring circuit measures the impedances in the tissue between electrodes of at least one electrode configuration according to a predetermined measurement scheme and an ischemia detector evaluates the measured impedance values using at least one reference impedance image of the heart to detect changes in the measured impedances that are consistent with an ischemia and to determine a location of the ischemia to at least one region of the image.
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Citations
43 Claims
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1. An implantable medical device comprising:
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a pulse generator that emits cardiac stimulation pulses; at least one medical lead connected to said pulse generator that delivers said stimulating pulses in vivo to cardiac tissue of a heart of a patient; an impedance measuring circuit that, during impedance measurement sessions, generates electrical signals applied between at least a first electrode and a second electrode, among electrodes carried by said at least one medical lead, in at least two electrode configurations according to a predetermined scheme, and that measures impedance in the tissue between said first electrode and said second electrode of each of said at least two electrode configurations; and an ischemia detector that evaluates the measured impedances by comparing the measured impedances with at least one reference impedance image of the heart comprising a plurality of impedance regions, to detect changes in the measured impedances that are consistent with ischemia, and that determines a location of said ischemia with respect to at least one of said regions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42)
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22. A method for operating an implantable medical device including a pulse generator that emits cardiac stimulating pulses and is connected to at least one medical lead for delivering said pulses in vivo to cardiac tissue of a heart of a patient, comprising the steps of:
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generating, during impedance measurement sessions, electrical signals to be applied between at least a first electrode and at least a second electrode among electrodes carried by said at least one medical lead in at least two electrode configurations according to a predetermined scheme; measuring the impedances in the tissue between said at least first electrode and said at least second electrode of said at least two electrode configurations to the applied electrical signals; and evaluating said measured impedance values including comparing said measured impedances with at least one reference impedance image of said heart comprising a number of impedance regions to detect changes in said measured impedances being consistent with an ischemia and to determine a location of said ischemia to at least one of said regions. - View Dependent Claims (23)
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43. A computer-readable medium encoded with programming instructions, said medium being loadable into a control unit of a medical device comprising a pulse generator that emits cardiac stimulating pulses and that is connected to at least one medical lead for delivering said pulses in vivo to cardiac tissue of a heart of a patient, and an impedance measuring circuit and a processor, said programming instructions causing said control unit to:
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operate said impedance circuit, during impedance measurement sessions, to apply electrical signals between at least a first electrode and at least a second electrode among electrodes carried by said at least one medical lead in at least two electrode configurations according to a predetermined scheme; operate said impedance circuit to measure impedances in tissue between said first electrode and said second electrode in each of said at least two electrode configurations; and operate said processor to evaluate the measured impedances by comparing the measured impedances with at least one reference impedance image of the heart comprising a plurality of impedance regions, to detect changes in the measured impedances that are consistent with ischemia, and to determine a location of said ischemia relative to at least one of said regions.
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Specification