Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier
First Claim
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1. A platelet preservation package, comprising:
- a platelet preservation composition comprising;
a short-to-ultra-short acting antiplatelet agent;
a short-to-ultra-short acting anticoagulant;
an oxygen carrier selected from the group consisting of hemoglobin, ferroprotoporphyrin, perfluorochemicals, and mixtures thereof; and
a container for storing the platelet preservation composition.
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Abstract
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use of a preservative composition having an antiplatelet agent, an anticoagulant, and an oxygen carrier, for maintaining the freshness of platelets. Additionally, the composition may also contain an ultra-short acting broad spectrum anti-microbial agents. The preservative composition may be used to store platelets in a liquid state, a frozen state, or a freeze-dried state.
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Citations
19 Claims
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1. A platelet preservation package, comprising:
- a platelet preservation composition comprising;
a short-to-ultra-short acting antiplatelet agent; a short-to-ultra-short acting anticoagulant; an oxygen carrier selected from the group consisting of hemoglobin, ferroprotoporphyrin, perfluorochemicals, and mixtures thereof; and a container for storing the platelet preservation composition. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
- a platelet preservation composition comprising;
Specification