Pyrido(3,2-d)pyrimidines useful for treating viral infections
First Claim
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1. A pyrido(3,2-d)pyrimidine derivative, having the structural formula:
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Abstract
2-amino-pyrido(3,2-d)pyrimidine derivatives with a specific substitution pattern on positions 4 and 6 of the core structure are useful in the treatment or prevention of an infection due to a virus from the Flaviviridae family, especially HCV, when administered to a patient in a therapeutically effective amount.
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2 Claims
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1. A pyrido(3,2-d)pyrimidine derivative, having the structural formula:
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2. A pyrido(3,2-d)pyrimidine derivative having the structural formula:
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Current AssigneeGilead Sciences Inc.
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Original AssigneeGilead Sciences Inc.
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InventorsWatkins, William John, Chong, Lee Shun, Zhang, Jennifer R.
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Primary Examiner(s)Kosar, Andrew D
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Assistant Examiner(s)Leeser, Erich A
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Application NumberUS12/519,496Publication NumberTime in Patent Office1,555 DaysField of Search514/264.1, 514/264.11, 544/279US Class Current544/279CPC Class CodesA61P 31/12 AntiviralsA61P 31/14 for RNA virusesC07D 471/04 Ortho-condensed systems
