System and methods for active suppression of superior tagging in flow-sensitive alternating inversion recovery

• US 8,143,892 B2
• Filed: 11/02/2009
• Issued: 03/27/2012
• Est. Priority Date: 10/31/2008
• Status: Expired due to Fees

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Briggs, Richard W., Li, Xiufeng, Gopinath, Kaundinya S., Sarkar, Subhendra N.
• Primary Examiner(s): SHRIVASTAV, BRIJ B
• Application Number:
  US12/610,876
• Publication Number:
  US 20100164496A1
• Time in Patent Office: 876 Days
• Field of Search: 324300-322, 600407-445
• US Class Current: 324/309
• CPC Class Codes: G01R 33/4833 using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices
• CPC Class Codes: G01R 33/56366 Perfusion imaging

Abstract

Apparatuses, systems, and methods for suppression of venous artifacts from superior tagging in flow-sensitive alternating inversion recovery. The systems may include an image capture device and a controller. The controller may be configured to cause the image capture device to perform a labeling experiment, capture a first image of a slice of body tissue, perform a control experiment, and capture a second image of the slice of body tissue. The systems may be configured to perform a ninety (90) degree RF saturation pulse directed to a portion of body tissue that is superior to the first slice of body tissue imaged during at least one of the labeling experiment and/or the control experiment, and to apply a spoiler gradient subsequent to the saturation pulse during at least one of the labeling experiment and/or the control experiment.

Claims

1. A method for active suppression of labeled venous blood signals in magnetic resonance imaging, the method comprising:

performing a labeling experiment;

capturing a first image of a slice of body tissue;

performing a control experiment;

capturing a second image of the slice of body tissue;

performing a ninety (90) degree RF saturation pulse directed to a portion of body tissue that is superior to one of the first slices of body tissue imaged during at least one of the labeling experiment and the control experiment; and

applying a spoiler gradient subsequent to the saturation pulse during at least one of the labeling experiment and the control experiment.

2. The method of claim 1, further comprising applying a plurality of ninety (90) degree RF saturation pulse.

3. The method of claim 2, further comprising applying a plurality of spoiler gradients, each spoiler gradient following a ninety (90) degree RF saturation pulse.

4. The method of claim 2, further comprising applying spoiler gradients subsequent to the plurality of ninety (90) degree RF saturation pulse.

5. The method of claim 2, further comprising applying a one-hundred-and-eighty (180) degree phase shift to one or more of the ninety (90) degree RF saturation pulses.

6. A system for active suppression of labeled venous blood signals in magnetic resonance imaging, the system comprising:

an image capture device comprising;

magnet;

one or more gradient coils; and

one or more RF coils; and

a controller unit configured to cause the image capture device to;

perform a labeling experiment;

capture a first image of a slice of body tissue;

perform a control experiment;

capture a second image of the slice of body tissue;

perform a ninety (90) degree RF saturation pulse directed to a portion of body tissue that is superior to one of the first slices of body tissue imaged during at least one of the labeling experiment and the control experiment; and

apply a spoiler gradient subsequent to the saturation pulse during at least one of the labeling experiment and the control experiment.

7. The system of claim 6, where the image capture device is further configured to apply a plurality of ninety (90) degree RF saturation pulse.

8. The system of claim 7, where the image capture device is further configured to apply a plurality of spoiler gradients, each spoiler gradient following a ninety (90) degree RF saturation pulse.

9. The system of claim 7, where the image capture device is further configured to apply spoiler gradients subsequent to the plurality of ninety (90) degree RF saturation pulse.

10. The system of claim 7, where the image capture device is further configured to apply a one-hundred-eighty (180) degree phase shift to one or more of the ninety (90) degree RF saturation pulses.

11. A non-transitory computer program product comprising a computer readable medium having computer usable program code executable to perform operations for active suppression of labeled venous blood signals in magnetic resonance imaging, the operations of the computer program product comprising:

performing a labeling experiment;

capturing a first image of a slice of body tissue;

performing a control experiment;

capturing a second image of the slice of body tissue;

performing a ninety (90) degree RF saturation pulse directed to a portion of body tissue that is superior to one of the first slices of body tissue imaged during at least one of the labeling experiment and the control experiment; and

applying a spoiler gradient subsequent to the saturation pulse during at least one of the labeling experiment and the control experiment.

12. The non-transitory computer program product of claim 11, where the operations further comprise applying a plurality of ninety (90) degree RF saturation pulse.

13. The non-transitory computer program product of claim 12, where the operations further comprise applying a plurality of spoiler gradients, each spoiler gradient following a ninety (90) degree RF saturation pulse.

14. The non-transitory computer program product of claim 12, where the operations further comprise applying spoiler gradients subsequent to the plurality of ninety (90) degree RF saturation pulse.

15. The non-transitory computer program product of claim 12, where the operations further comprise applying a one-hundred-eighty (180) degree phase shift to one or more of the ninety (90) degree RF saturation pulses.