Noninvasive measuring device for substance in blood via nail and a nail evaporation device
First Claim
1. A device for optically measuring a test substance in blood by using a nail as an optical window which comprises:
- (i) a nail plate evaporation device, which partly removes a nail plate by evaporating the nail plate for creating an optical window in the nail, which comprises (a) a light generator generating a coherent light, (b) an evaporation depth monitor having a light detector detecting fluorescence emitted from the nail plate and the dermis for monitoring evaporation depth of the nail plate, and a controller which processes the detected fluorescence to determine evaporation depth information of the nail plate for controlling the light generator;
(ii) an irradiator configured to apply light within a wavelength range for measuring absorption by the test substance through the optical window;
(iii) a detector configured to detect light diffused/reflected from or transmitted through the body of a subject;
(iv) a processor configured to process a signal obtained by the detector to convert the signal into a concentration of the test substance;
(v) a monitor configured to monitor a water content and a keratin content of the nail by using light within a wavelength range for measuring absorption by water in the nail and light within a wavelength range for measuring absorption by keratin in the nail to correct or eliminate optical characteristics of the nail plate in the detected light.
1 Assignment
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Accused Products
Abstract
A device and method for optically measuring a substance in blood using the nail as an optical window are provided. A device for optically measuring a test substance in blood by using the nail as an optical window and correcting or eliminating fluctuation of a measurement value based on optical characteristics of the nail plate, comprising irradiation means applying light within a wavelength range for measuring absorption by the test substance to the nail of a subject, detection means detecting light diffused/reflected from or transmitted through the body of the subject, and processing means processing a signal obtained by the detection means to convert the signal into a concentration of the test substance.
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Citations
13 Claims
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1. A device for optically measuring a test substance in blood by using a nail as an optical window which comprises:
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(i) a nail plate evaporation device, which partly removes a nail plate by evaporating the nail plate for creating an optical window in the nail, which comprises (a) a light generator generating a coherent light, (b) an evaporation depth monitor having a light detector detecting fluorescence emitted from the nail plate and the dermis for monitoring evaporation depth of the nail plate, and a controller which processes the detected fluorescence to determine evaporation depth information of the nail plate for controlling the light generator; (ii) an irradiator configured to apply light within a wavelength range for measuring absorption by the test substance through the optical window; (iii) a detector configured to detect light diffused/reflected from or transmitted through the body of a subject; (iv) a processor configured to process a signal obtained by the detector to convert the signal into a concentration of the test substance; (v) a monitor configured to monitor a water content and a keratin content of the nail by using light within a wavelength range for measuring absorption by water in the nail and light within a wavelength range for measuring absorption by keratin in the nail to correct or eliminate optical characteristics of the nail plate in the detected light. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification