System and method for determining the concentration of an analyte in a sample fluid
First Claim
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1. A method for determining a concentration of a medically significant component of a biological fluid in contact with a reagent compound, comprising the steps of:
- a) applying a first signal having an AC component to the biological fluid;
b) measuring a first response to the first signal;
c) applying a second signal to the biological fluid, wherein the second signal is a DC signal;
d) measuring a second response to the second signal; and
e) combining the first response with the second response to produce an indication of the concentration of the medically significant component;
wherein said first signal comprises a multi-frequency excitation waveform formed by adding a plurality of individual waveforms of varying frequency together so that the fluid sample is excited by multiple frequencies at the same time such that the first response contains measurement data collected simultaneously for all of the multiple frequencies.
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Abstract
The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 2.0 seconds or less, and/or having a clinically low Total System Error.
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Citations
11 Claims
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1. A method for determining a concentration of a medically significant component of a biological fluid in contact with a reagent compound, comprising the steps of:
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a) applying a first signal having an AC component to the biological fluid; b) measuring a first response to the first signal; c) applying a second signal to the biological fluid, wherein the second signal is a DC signal; d) measuring a second response to the second signal; and e) combining the first response with the second response to produce an indication of the concentration of the medically significant component; wherein said first signal comprises a multi-frequency excitation waveform formed by adding a plurality of individual waveforms of varying frequency together so that the fluid sample is excited by multiple frequencies at the same time such that the first response contains measurement data collected simultaneously for all of the multiple frequencies. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification