Systems and methods for replacing signal artifacts in a glucose sensor data stream
First Claim
1. In a glucose sensing system comprising a glucose sensor configured for producing an output representative of glucose concentration in a host and processing circuitry configured to process the output, a method for processing data from the output, the method comprising:
- generating at least one data stream from the glucose sensor output;
detecting signal loss, wherein detecting signal loss comprises monitoring the data stream to identify a negative rate of change and determining that the negative rate of change exceeds a predetermined threshold;
generating an estimated data stream or data stream portion to reduce or replace the signal loss; and
outputting to an external device or displaying the at least one estimated data stream or data stream portion.
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Accused Products
Abstract
Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
604 Citations
32 Claims
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1. In a glucose sensing system comprising a glucose sensor configured for producing an output representative of glucose concentration in a host and processing circuitry configured to process the output, a method for processing data from the output, the method comprising:
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generating at least one data stream from the glucose sensor output; detecting signal loss, wherein detecting signal loss comprises monitoring the data stream to identify a negative rate of change and determining that the negative rate of change exceeds a predetermined threshold; generating an estimated data stream or data stream portion to reduce or replace the signal loss; and outputting to an external device or displaying the at least one estimated data stream or data stream portion. - View Dependent Claims (2, 3, 4, 5)
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6. A glucose sensor system for monitoring a glucose concentration in a host, the system comprising:
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a continuous glucose sensor configured to produce an output; a signal processing module configured to generate a data stream based on the output; a signal loss detector configured to detect signal loss by monitoring the data stream to identify a negative rate of change and determining that the negative rate of change exceeds a predetermined threshold;
a signal estimator configured to generate an estimated data stream or data stream portion to reduce or replace the signal loss; anda user interface configured to display information representative of the estimated data stream or data stream portion responsive to detecting signal loss. - View Dependent Claims (7, 8, 9, 10)
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11. In a glucose sensing system comprising a glucose sensor configured for producing an output representative of glucose concentration in a host and processing circuitry configured to process the output, a method for processing data from the output, the method comprising:
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generating at least one data stream from the glucose sensor output; detecting signal loss, wherein detecting signal loss comprises evaluating the at least one data stream for a high frequency content that exceeds a predetermined threshold; generating an estimated data stream or data stream portion to reduce or replace the signal loss; and outputting to an external device or displaying the at least one estimated data stream or estimated data stream portion. - View Dependent Claims (12, 13, 14, 15, 16)
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17. A glucose sensor system for monitoring a glucose concentration in a host, the system comprising:
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a continuous glucose sensor configured to produce a sensor output; a signal processing module configured to generate a data stream from the glucose sensor output; a signal loss detector configured to detect signal loss by evaluating the data stream for a high frequency content that exceeds a predetermined threshold; a signal estimator configured to generate an estimated data stream or data stream portion to reduce or replace the signal loss; and a user interface configured to display information representative of the estimated data stream or data stream portion responsive to the evaluating. - View Dependent Claims (18, 19, 20, 21, 22)
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23. In a glucose sensing system comprising a glucose sensor configured for producing an output representative of glucose concentration in a host and processing circuitry configured to process the output, a method for processing data from the output, the method comprising:
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generating at least one data stream from a glucose sensor output; detecting signal loss, wherein detecting signal loss comprises monitoring the data stream to identify an acceleration and determining that the acceleration exceeds a predetermined threshold; generating an estimated data stream or data stream portion to reduce or replace the signal loss; and outputting to an external device or displaying the at least one estimated data stream or data stream portion. - View Dependent Claims (24, 25, 26, 27)
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28. A glucose sensor system for monitoring a glucose concentration in a host, the system comprising:
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a continuous glucose sensor configured to produce an output; a signal processing module configured to generate a data stream based on the output; a signal loss detector configured to detect signal loss by monitoring the data stream to identify an acceleration and determining that the acceleration exceeds a predetermined threshold;
a signal estimator configured to generate an estimated data stream or data stream portion to reduce or replace the signal loss; anda user interface configured to display information representative of the estimated data stream or data stream portion responsive to detecting signal loss. - View Dependent Claims (29, 30, 31, 32)
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Specification