Method and device for cardiac tissue ablation

• US 8,152,795 B2
• Filed: 04/14/2008
• Issued: 04/10/2012
• Est. Priority Date: 07/14/1999
• Status: Expired due to Term

• Current Assignee: Cardiofocus Incorporated
• Original Assignee: Cardiofocus Incorporated
• Inventors: Farr, Norman E., Wieler, William E.
• Primary Examiner(s): FARAH, AHMED M
• Application Number:
  US12/102,466
• Publication Number:
  US 20080195088A1
• Time in Patent Office: 1,457 Days
• Field of Search: 606 7- 9, 606 13- 18, 607/88, 607/89, 607 92- 94, 128/898
• US Class Current: 606/7
• CPC Class Codes: A61B 18/245 for removing obstructions in blood vessels or calculi
• CPC Class Codes: A61B 2017/00061 spectrum
• CPC Class Codes: A61B 2018/0097 Cleaning probe surfaces
• CPC Class Codes: A61B 2018/2266 with a lens, e.g. ball tipped
• CPC Class Codes: A61B 2018/2272 with reflective or refractive surfaces for deflecting the beam A61B2018/2261, A61B2018/2266 take precedence
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure

Abstract

Methods and apparatus are disclosed for forming annular lesions in tissue. The methods include introduction of an optical apparatus proximate to a tissue site, via, for example, a catheter. The optical apparatus includes a pattern-forming optical wave guide in communication with a light transmitting optical fiber. Energy is transmitted through the optical fiber, such that radiation is propagated through the optical fiber and the wave guide projects an annular light pattern, e.g., a circle or a halo.

Claims

1. A cardiac ablation instrument for preventative treatment to inhibit exigent physiological aberrations at a treatment site, comprising:

a catheter body configured for disposition within a heart;

a non-contact energy emitter being slidably disposed within a lumen of the catheter, the non-contact energy emitter configured to forwardly project ablative energy to a target tissue at the treatment site, wherein the non-contact energy emitter is configured and disposed within the catheter such that sliding the energy emitter along the lumen of the catheter permits control over an amount or a shape of ablative energy being projected towards the target tissue;

a reflectance fiber supported by the catheter body, the reflectance fiber being part of a reflective monitor;

a controller in communication with the reflectance fiber and configured to use reflective feedback from the reflectance fiber in order to monitor the state of ablation at the treatment site;

a display providing a visual display of the state of the target tissue, wherein the controller is further configured to provide visual feedback signals to the display that are indicative of at least an onset of tissue carbonization and provide visual feedback to a user.

2. The instrument of claim 1, further comprising an expandable balloon coupled to a distal portion of the catheter body.

3. The instrument of claim 2, wherein the balloon is energy transparent.

4. The instrument of claim 1, wherein the controller is configured to adjust an amount of ablative energy based upon a signal provided by the reflectance monitor to the controller.

5. The instrument of claim 4, wherein the display comprises a real-time display of the target tissue.

6. The instrument of claim 1, wherein the non-contact energy emitter is selected from the group consisting of a laser energy emitter, an ultraviolet light energy emitter, a microwave radiation energy emitter, a radiofrequency energy emitter.

7. The instrument of claim 1, wherein the non-contact energy emitter is configured to forwardly project an annular ring of ablative energy to the target tissue.

8. The instrument of claim 7, wherein the energy emitter comprises an optical fiber and an energy focusing element that cooperate to forwardly project the annular ring of ablative energy.

9. The instrument of claim 7, wherein the non-contact energy emitter is configured and disposed within the catheter such that sliding the energy emitter along the lumen of the catheter permits control over an amount or a size of the annular ring of ablative energy being projected towards the target tissue.

10. A cardiac ablation instrument for treating atrial fibrillation at a treatment site, comprising:

a catheter body adapted for disposition within a heart;

an inflatable balloon coupled to the catheter body and adapted to engage cardiac tissue near a pulmonary vein upon inflation;

an energy emitter disposed within a distal region of the catheter body, and adapted to be slidably adjustable and independently positionable within the catheter body, the energy emitter being configured to forwardly project ablative energy to create a lesion at a target tissue site near a pulmonary vein;

a display providing a visual display of the state of the target tissue site;

a reflectance fiber supported by the catheter body; and

a controller in communication with the reflectance fiber and configured to use reflective feedback from the reflectance fiber in order to monitor the state of ablation at the target tissue site, the controller being further configured to provide visual feedback signals to the display that are indicative of at least an onset of tissue carbonization.

11. The instrument of claim 10, wherein the balloon is further adapted to clear a transmission pathway for projecting the ablative energy from the energy emitter to the target tissue site.

12. The instrument of claim 10, wherein the instrument is adapted to project energy forward.

13. The instrument of claim 10, wherein the instrument is adapted to project energy forward at an angle from a central axis of the catheter body.

14. The instrument of claim 10, further comprising a positioning element to modify the path of projected energy, the positioning element being situated at a distal end of the energy emitter.

15. The instrument of claim 10, further comprising at least one energy focusing element, the energy focusing element being situated at a distal end of the energy emitter.

16. The instrument of claim 10, wherein the instrument is configured to create an annular lesion.

17. The instrument of claim 10, wherein the instrument is configured to create a lesion of variable size.

18. The instrument of claim 10, wherein the instrument is configured to create a lesion on an atrial wall.

19. The instrument of claim 10, wherein the instrument is configured to create a lesion around a pulmonary vein.

20. The instrument of claim 10, wherein the instrument is configured to create a lesion at an interface between a pulmonary vein and an atrial wall region.

21. The instrument of claim 10, further comprising a sensor for detecting energy reflected from target tissue.

22. The instrument of claim 10, further comprising a sensor adapted to monitor ablation based on reflected energy.

23. A method of treating atrial fibrillation, comprising:

positioning a distal portion of an ablation instrument in proximity to a pulmonary vein, the instrument having a lumen configured to slidably receive an independently positionable energy emitter within the distal portion of the instrument;

inflating a balloon element coupled to the distal portion of the instrument such that the balloon element contacts a treatment site;

sliding the energy emitter to a desired position relative to the lumen;

activating the energy emitter so as to forwardly transmit energy to the treatment site and thereby form an annular lesion in proximity to the pulmonary vein; and

monitoring an amount of light reflected from a treatment site to detect a state of ablation of a target tissue including at least an onset of tissue carbonization.

24. The method of claim 23, wherein sliding the energy emitter to various positions along the lumen results in various sizes of an annular ring of ablative energy being delivered to the treatment site.

25. The method of claim 23, further comprising monitoring a reflected light by a reflectance monitor wherein the reflected light is indicative a state of ablation of the treatment site.