Methods for treating fractured and/or diseased bone by introduction of different bone filling materials

• US 8,152,813 B2
• Filed: 09/27/2006
• Issued: 04/10/2012
• Est. Priority Date: 08/14/1998
• Status: Expired due to Fees

• Current Assignee: Orthophoenix, LLC (Marathon Patent Group, Inc.)
• Original Assignee: Kyphon SARL (Medtronic Plc)
• Inventors: Osorio, Reynaldo A, Follmer, Marialulu, Layne, Richard W, Boucher, Ryan P, Talmadge, Karen D, Basista, Joseph J
• Primary Examiner(s): Barrett, Thomas C.
• Assistant Examiner(s): CARTER, TARA ROSE E
• Application Number:
  US11/527,838
• Publication Number:
  US 20070055382A1
• Time in Patent Office: 2,022 Days
• Field of Search: 606 92- 94, 606/90, 606/105, 623/16.11, 623 1711- 1716
• US Class Current: 606/94
• CPC Class Codes: A61B 17/1604 Chisels; Rongeurs; Punches; Stamps
• CPC Class Codes: A61B 17/1671 for the spine
• CPC Class Codes: A61B 17/3472 for bones, e.g. intraosseus injections
• CPC Class Codes: A61B 17/8805 for introducing fluid filler into bone or extracting it A61B17/7097, A61B17/8833 take precedence
• CPC Class Codes: A61B 17/8855 inflatable, e.g. kyphoplasty balloons
• CPC Class Codes: A61B 2017/00261 Discectomy
• CPC Class Codes: A61B 2017/00464 for use with different instruments with hole for different instruments A61B2017/22072
• CPC Class Codes: A61B 2017/00539 hydraulically
• CPC Class Codes: A61B 2017/00557 inflatable A61B2017/22051 takes precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2050/0065 Peelable cover
• CPC Class Codes: A61B 2090/062 penetration depth
• CPC Class Codes: A61B 50/33 Trays
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/44 for the spine, e.g. vertebrae, spinal discs
• CPC Class Codes: A61F 2/4601 for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
• CPC Class Codes: A61F 2/4603 for insertion or extraction of endoprosthetic joints or of accessories thereof
• CPC Class Codes: A61F 2002/2835 Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
• CPC Class Codes: A61F 2002/3008 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2002/30581 having a pocket filled with fluid, e.g. liquid
• CPC Class Codes: A61F 2002/4635 : using minimally invasive surgery
• CPC Class Codes: A61F 2002/4662 : for measuring penetration depth
• CPC Class Codes: A61F 2250/0098 : radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2310/00353 : Bone cement, e.g. polymethylmethacrylate or PMMA

Abstract

A percutaneous path is established into a selected bone, e.g., a vertebral body, having an interior volume occupied, at least in part, by cancellous bone. A first bone filling material is conveyed through the percutaneous path into a region of the cancellous bone. A second bone filling material is conveyed through the percutaneous path into the region. The second bone filling material is different than the first bone filling material.

Claims

1. A method comprising:

selecting a bone having an interior volume occupied, at least in part, by cancellous bone,

establishing a percutaneous path into the bone, the percutaneous path including an opening into the bone,

conveying only a first bone filling material through the percutaneous path to deposit the first bone filling material into a region of the cancellous bone, and

after depositing the first bone filling material into the region, conveying only a second bone filling material different than the first bone filling material through the percutaneous path into the region and adjacent to the previously deposited first bone filling material in the region,

wherein the first and second bone filling materials are conveyed into the region of the cancellous bone via the opening into the bone, wherein the first bone filling material comprises a first settable material,

wherein the second bone filling material comprises a second settable material, and

further including accelerating setting of the first settable material in advance of the second settable material.

2. A method comprising:

selecting a bone having an interior volume occupied, at least in part, by cancellous bone,

establishing a percutaneous path into the bone, the percutaneous path including an opening into the bone,

conveying only a first bone filling material through the percutaneous path to deposit the first bone filling material into a region of the cancellous bone, and

after depositing the first bone filling material into the region, conveying only a second bone filling material different than the first bone filling material through the percutaneous path into the region and adjacent to the previously deposited first bone filling material in the region,

wherein the first and second bone filling materials are conveyed into the region of the cancellous bone via the opening into the bone, wherein the first bone filling material comprises a first settable material,

wherein the second bone filling material comprises a second settable material, and

further including retarding setting of the second settable material behind the first settable material.

3. A method comprising:

selecting a bone having an interior volume occupied, at least in part, by cancellous bone,

establishing a percutaneous path into the bone, the percutaneous path including an opening into the bone,

conveying only a first bone filling material through the percutaneous path to deposit the first bone filling material into a region of the cancellous bone, and

after depositing the first bone filling material into the region, conveying only a second bone filling material different than the first bone filling material through the percutaneous path into the region and adjacent to the previously deposited first bone filling material in the region,

wherein the first and second bone filling materials are conveyed into the region of the cancellous bone via the opening into the bone, wherein the first bone filling material comprises a first settable material having a cure time,

wherein the second bone filling material comprises a second settable material having a cure time greater than the cure time of the first settable material.

4. A method comprising:

selecting a bone having an interior volume occupied, at least in part, by cancellous bone,

establishing a percutaneous path into the bone, the percutaneous path including an opening into the bone,

conveying only a first bone filling material through the percutaneous path to deposit the first bone filling material into a region of the cancellous bone, and

after depositing the first bone filling material into the region, conveying only a second bone filling material different than the first bone filling material through the percutaneous path into the region and adjacent to the previously deposited first bone filling material in the region,

wherein the first and second bone filling materials are conveyed into the region of the cancellous bone via the opening into the bone, wherein the first bone filling material comprises material more resistant to extravazation in the cancellous bone than the second bone filling material.

5. A method comprising:

selecting a bone having an interior volume occupied, at least in part, by cancellous bone,

establishing a percutaneous path into the bone, the percutaneous path including an opening into the bone,

conveying only a first bone filling material through the percutaneous path to deposit the first bone filling material into a region of the cancellous bone, and

after depositing the first bone filling material into the region, conveying only a second bone filling material different than the first bone filling material through the percutaneous path into the region and adjacent to the previously deposited first bone filling material in the region, and

wherein the first and second bone filling materials are conveyed into the region of the cancellous bone via the opening into the bone, wherein the first and second bone filing materials comprises particles, and

wherein the particles of the first bone filling material are larger than the particles in the second bone filling material.

6. A method comprising:

selecting a bone having an interior volume occupied, at least in part, by cancellous bone,

establishing a percutaneous path into the bone,

conveying only a first bone filling material through the percutaneous path to deposit the first bone filling material into a region of the cancellous bone,

after depositing the first bone filling material into the region, conveying only a second bone filling material different than the first bone filling material through the percutaneous path into the region and adjacent to the previously deposited first bone filling material in the region, and

allowing the first bone filling material to harden around the expandable structure,

wherein the region includes a cavity formed in cancellous bone, and

wherein the cavity is formed by an expandable structure introduced through the percutaneous path.

7. A method comprising:

selecting a bone having an interior volume occupied, at least in part, by cancellous bone,

establishing a percutaneous path into the bone by positioning a shaft into the interior volume through an opening of the bone,

conveying a first bone filling material through the shaft to deposit the first bone filling material into a region of the cancellous bone, and

repositioning the shaft through the opening such that a distal tip of the shaft is positioned within the first bone filling material previously conveyed into the region of the cancellous bone,

after repositioning the shaft, conveying a second bone filling material different than the first bone filling material through the distal tip of the shaft positioned within the first bone filling material such that the second bone filling material is conveyed within the first bone filling material.