System, device, and method for mixing a substance with a liquid

• US 8,158,102 B2
• Filed: 10/30/2003
• Issued: 04/17/2012
• Est. Priority Date: 10/30/2003
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Demers, Jason A., Dale, James D., Tracey, Brian, McGill, David W., Gray, Larry B.
• Primary Examiner(s): CORDERO GARCIA, MARCELA M
• Application Number:
  US10/696,969
• Publication Number:
  US 20050095576A1
• Time in Patent Office: 3,092 Days
• Field of Search: 366/167.1, 604/403, 604/411, 604/415, 604/416, 435/4, 423/658.5
• US Class Current: 423/658.5
• CPC Class Codes: A61M 1/0281 Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/3687 Chemical treatment A61M1/3675 takes precedence
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: B01F 33/81 Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
• CPC Class Codes: B01F 33/811 in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
• CPC Class Codes: B01F 35/711 for feeding a mixture of components, i.e. solids in liquid, solids in a gas stream
• CPC Class Codes: B01F 35/715 Feeding the components in several steps, e.g. successive steps

Abstract

A system, device, and method for mixing a substance with a liquid pumps the liquid into a container of the substance to produce a solution. The container may be part of a container assembly including a port assembly for coupling with the container to produce an inlet and/or and outlet port for the container. The container assembly may be received within a receiving chamber for causing the coupling. The solution may be permitted to flow out of the outlet port when the solution rises within the container to a level of the outlet port so that the substance is partially diluted before flowing out of the outlet port.

Claims

1. An apparatus for mixing a substance in a sealed container with a liquid, the container being positioned in a container receptacle, the container receptacle configured to couple with a port assembly to permit liquid to enter the container through the port assembly, the apparatus comprising:

a container spiking assembly comprising a movable member adapted to move the container receptacle toward the port assembly;

a container spiking assembly controller in communication with the container spiking assembly for controlling coupling of the container receptacle with the port assembly; and

a liquid controller for controlling the flow of the liquid through the port assembly into the container to produce a combined substance and liquid, wherein;

the container spiking assembly controller is configured to control the movement of the movable member of the container spiking assembly to couple the container receptacle with the port assembly while the port assembly is immobilized relative to the container receptacle, and wherein upon coupling, the container receptacle and port assembly are configured to lock together through engagement of one or more engagement teeth between the container receptacle and the port assembly.

2. The apparatus as defined by claim 1 wherein the liquid controller also controls the flow of combined substance and liquid from the container.

3. The apparatus as defined by claim 1 wherein the container spiking assembly controller includes logic for determining the relative locations of the container receptacle and the port assembly, using input from at least one sensor associated with the container spiking assembly.

4. The apparatus as defined by claim 1 wherein the container spiking assembly further comprises a cover capable of being in either an open position or a closed position, the cover securing the container receptacle and port assembly within the container spiking assembly when in the closed position, and the container spiking assembly controller having logic for determining if the cover is in the closed position.

5. The apparatus as defined by claim 4 wherein the container spiking assembly controller includes logic to direct the container receptacle to couple with the port assembly after detecting that the cover is in the closed position.

6. The apparatus as defined by claim 4 further including a cover lock that prevents the cover from being moved from the closed position while the liquid is being received by the container.

7. The apparatus as defined by claim 1 further including a pneumatically controlled member within the container spiking assembly, the pneumatically controlled member capable of contributing to the coupling of the container receptacle with the port assembly in response to input from the container spiking assembly controller.

8. The apparatus as defined by claim 1 wherein the liquid controller includes stored commands for directing the delivery of a predetermined amount of liquid to the container via the port assembly.

9. The apparatus as defined by claim 1 further comprising a housing containing at least one of the container spiking assembly controller and the liquid controller.

10. The apparatus as defined by claim 9 wherein the container spiking assembly at least partially extends outwardly from the housing.

11. The apparatus as defined by claim 1 further comprising a sensor within the container spiking assembly for detecting the location of the container relative to the port assembly.

12. The apparatus as defined by claim 1 wherein the container spiking assembly is configured to contain the container receptacle in a single orientation.

13. The apparatus as defined by claim 1 further comprising a set of valves controlled by the liquid controller to control the flow of liquid into the container.

14. The apparatus as defined by claim 1 further comprising a pump chamber used by the liquid controller to measure the volume of the liquid to be directed to the container.

15. The apparatus as defined by claim 1 wherein the substance is a caustic solution.

16. The apparatus as defined by claim 1 wherein the substance is an anti-pathogen compound.

17. The apparatus as defined by claim 1, wherein the container receptacle comprises a plurality of engagement teeth, and wherein a locking feature on the port assembly engages one or more of the plurality of engagement teeth.

18. The apparatus as defined by claim 17, wherein the container receptacle includes a plurality of tabs, each tab having engagement teeth, wherein the engagement teeth on adjacent tabs are staggered relative to one another.

19. The apparatus as defined by claim 18, wherein the engagement teeth are staggered by approximately half the height of one of the engagement teeth.

20. The apparatus defined by claim 11, wherein the container receptacle comprises at least one raised switch engagement feature on an outer surface of the container receptacle for operating a sensor within the container spiking assembly.

37. The apparatus as defined by claim 1 wherein the container spiking assembly has a cover for securing the port assembly within the container spiking assembly, and wherein the container spiking assembly controller is configured to control the movement of the container within the container spiking assembly so as to connect the container with a fluid flow lumen of the port assembly.

38. The apparatus is defined by claim 7 further including an inflatable bladder in communication with the pneumatically controlled member for pneumatic control of the pneumatically controlled member in response to input from the container spiking assembly controller.

21. An apparatus for mixing a substance in a sealed container with a liquid, the container being positioned in a container receptacle, the container receptacle configured to couple with a port assembly to permit liquid to enter the container through the port assembly the apparatus comprising:

positioning means for moving the container receptacle toward the port assembly;

coupling means for controlling coupling of the container receptacle with the port assembly; and

flow means for controlling the flow of the liquid into the container to produce a combined substance and liquid, wherein;

the positioning means is configured for movement of the container receptacle toward the port assembly while the port assembly is immobilized relative to the container receptacle, and wherein upon coupling, the container receptacle and port assembly are configured to lock together through engagement of one or more engagement teeth between the container receptacle and the port assembly.

22. The apparatus as defined by claim 21 wherein the flow means also controls the flow of combined substance and liquid from the container.

23. The apparatus as defined by claim 21 wherein the coupling means includes means for determining the relative locations of the container receptacle and the port assembly, using input from at least one sensor associated with the positioning means.

24. The apparatus as defined by claim 21 wherein the positioning means includes a cover capable of being in either an open position or a closed position, the cover securing the container receptacle and port assembly within the positioning means when in the closed position, and the coupling means having means for determining if the cover is in the closed position.

25. The apparatus as defined by claim 24 wherein the coupling means includes logic to direct the container receptacle to couple with the port assembly after detecting that the cover is in the closed position.

26. The apparatus as defined by claim 24 further including a cover lock that prevents the cover from being moved from the closed position while the liquid is being received by the container.

27. The apparatus as defined by claim 21 further including a pneumatically controlled means within the positioning means, the pneumatically controlled means capable of contributing to the coupling of the container receptacle with the port assembly in response to input from the coupling means.

28. The apparatus as defined by claim 21 wherein the flow means includes means for controlling the delivery of a predetermined amount of liquid to the container via the port assembly.

29. The apparatus as defined by claim 21 further comprising a housing containing at least one of the coupling means and the flow means.

30. The apparatus as defined by claim 29 wherein the positioning means at least partially extends outwardly from the housing.

31. The apparatus as defined by claim 21 further comprising a means for detecting the location of the container relative to the port assembly.

32. The apparatus as defined by claim 21 wherein the positioning means is configured to contain the container receptacle in a single orientation.

33. The apparatus as defined by claim 21 further comprising a set of valves controlled by the flow means to control the flow of liquid into the container.

34. The apparatus as defined by claim 21 further comprising a means for measuring the volume of the liquid to be directed to the container, the measuring means being used by the flow means.

35. The apparatus as defined by claim 21 wherein the substance is a caustic substance.

36. The apparatus as defined by claim 21 wherein the substance is an anti-pathogen compound.

39. The apparatus as defined by claim 21 wherein the positioning means is cylindrical.

40. The apparatus as defined by claim 21 wherein positioning means includes means for securing the port assembly and wherein the coupling means includes means for moving the container so as to couple the container with a fluid flow lumen of the port assembly.

41. The apparatus as defined by claim 27 wherein the pneumatically controlled means includes a pneumatically controlled member and an inflatable means in communication with the pneumatically controlled member for pneumatic control of the pneumatically controlled member in response to input from the coupling means.