Transcutaneous analyte sensor
First Claim
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1. A system for monitoring a glucose concentration in a host, the system comprising:
- a continuous glucose sensor configured to produce a signal indicative of a glucose concentration in a host;
monitoring system electronics operably connected to the sensor and configured to receive reference data from a single point glucose measuring device, the single point glucose measuring device configured to receive a biological sample from the host and to measure a concentration of glucose in the biological sample, wherein the reference data is indicative of a measured glucose concentration in the biological sample, wherein the monitoring system electronics are configured to provide real-time calibrated glucose concentration values of the host based on the signal, and wherein providing the real-time calibrated glucose concentration values comprises evaluating an acceptability of the reference data in real time using a clinical acceptability grid, and calibrating or confirming the signal responsive to the acceptability evaluation of the reference data.
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Abstract
The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
990 Citations
26 Claims
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1. A system for monitoring a glucose concentration in a host, the system comprising:
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a continuous glucose sensor configured to produce a signal indicative of a glucose concentration in a host; monitoring system electronics operably connected to the sensor and configured to receive reference data from a single point glucose measuring device, the single point glucose measuring device configured to receive a biological sample from the host and to measure a concentration of glucose in the biological sample, wherein the reference data is indicative of a measured glucose concentration in the biological sample, wherein the monitoring system electronics are configured to provide real-time calibrated glucose concentration values of the host based on the signal, and wherein providing the real-time calibrated glucose concentration values comprises evaluating an acceptability of the reference data in real time using a clinical acceptability grid, and calibrating or confirming the signal responsive to the acceptability evaluation of the reference data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A system comprising one or more processors and computer readable memory, the computer readable memory comprising code that, when executed by the one or more processors, causes the one or more processors to:
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process a signal received from a continuous glucose measuring device; measure a concentration of glucose in a biological sample received from a host, the measured glucose concentration in the sample comprising reference data; and provide real-time calibrated glucose concentration values of the host based on the signal, wherein providing the real-time calibrated glucose concentration values comprises evaluating an acceptability of the reference data in real time using a clinical acceptability grid, and calibrating or confirming the signal responsive to the acceptability evaluation of the reference data. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
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19. A method for monitoring glucose concentration in a host, the method comprising:
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generating a signal from a continuous glucose measuring device indicative of a glucose concentration in a host; measuring a concentration of glucose in a biological sample in a single point glucose measuring device, the measured glucose concentration in the biological sample comprising reference data; providing, using monitoring system electronics of a monitoring system, real-time calibrated glucose concentration values of the host based on the signal, wherein providing the real-time calibrated glucose concentration values comprises evaluating an acceptability of the reference data in real time using a clinical acceptability grid and calibrating or confirming the signal responsive to the acceptability evaluation of the reference data. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26)
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Specification