Standalone systemic arterial blood pressure monitoring device
First Claim
1. An implantable monitoring device to monitor a patient'"'"'s arterial blood pressure and configured to be implanted subcutaneously, the device comprising:
- subcutaneous (SubQ) electrodes configured to obtain a subcutaneous electrocardiogram (SubQ ECG) that is indicative of electrical activity of the patient'"'"'s heart;
a plethysmography sensor configured to obtain a plethysmography signal indicative of changes in the patient'"'"'s arterial blood volume; and
an arterial blood pressure monitor configured todetect a predetermined feature of the SubQ ECG signal indicative of ventricular depolarization,detect a predetermined feature of the SubQ ECG signal indicative of ventricular repolarization,detect a predetermined feature of the plethysmography signal, anddetermine a time t1 from the predetermined feature of the SubQ ECG indicative of ventricular depolarization to the predetermined feature of the plethysmography signal,determine a time t2 from the predetermined feature of the SubQ ECG indicative of ventricular repolarization to the predetermined feature of the plethysmography signal, anddetermine at least one value indicative of the patient'"'"'s arterial blood pressure based on the times t1 and t2 determined from the SubQ ECG signal and the plethysmography signal.
1 Assignment
0 Petitions
Accused Products
Abstract
Certain embodiments of the present invention are related to an implantable monitoring device to monitor a patient'"'"'s arterial blood pressure, where the device is configured to be implanted subcutaneously. The device includes subcutaneous (SubQ) electrodes and a plethysmography sensor. Additionally, the device includes an arterial blood pressure monitor configured to determine at least one value indicative of the patient'"'"'s arterial blood pressure based on at least one detected predetermined feature of a SubQ ECG and at least one detected predetermined feature of a plethysmography signal. Alternative embodiments of the present invention are directed to a non-implantable monitoring device to monitor a patient'"'"'s arterial blood pressure based on features of a surface ECG and a plethysmography signal obtained from a non-implanted sensor.
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Citations
29 Claims
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1. An implantable monitoring device to monitor a patient'"'"'s arterial blood pressure and configured to be implanted subcutaneously, the device comprising:
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subcutaneous (SubQ) electrodes configured to obtain a subcutaneous electrocardiogram (SubQ ECG) that is indicative of electrical activity of the patient'"'"'s heart; a plethysmography sensor configured to obtain a plethysmography signal indicative of changes in the patient'"'"'s arterial blood volume; and an arterial blood pressure monitor configured to detect a predetermined feature of the SubQ ECG signal indicative of ventricular depolarization, detect a predetermined feature of the SubQ ECG signal indicative of ventricular repolarization, detect a predetermined feature of the plethysmography signal, and determine a time t1 from the predetermined feature of the SubQ ECG indicative of ventricular depolarization to the predetermined feature of the plethysmography signal, determine a time t2 from the predetermined feature of the SubQ ECG indicative of ventricular repolarization to the predetermined feature of the plethysmography signal, and determine at least one value indicative of the patient'"'"'s arterial blood pressure based on the times t1 and t2 determined from the SubQ ECG signal and the plethysmography signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. An implantable monitoring device to monitor a patient'"'"'s arterial blood pressure, the device comprising:
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subcutaneous (SubQ) electrodes configured to obtain a subcutaneous electrocardiogram (SubQ ECG) that is indicative of electrical activity of the patient'"'"'s heart; a plethysmography sensor configured to obtain a plethysmography signal indicative of changes in the patient'"'"'s arterial blood volume; and an arterial blood pressure monitor configured to detect ventricular depolarizations and ventricular repolarizations in cardiac cycles represented in the SubQ ECG signal; detect maximum peak amplitudes in cardiac cycles represented in the PPG signal; determine a time t1 from a detected ventricular depolarization to a detected maximum peak amplitude in the plethysmography signal; determine a time t2 from a detected ventricular repolarization to the detected maximum peak amplitude in the plethysmography signal; determine a peak pulse arrival time (PPAT) based on times t1 and t2; and determine a value indicative of systolic pressure (SP) based on the PPAT. - View Dependent Claims (21, 22, 23)
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24. An implantable monitoring device to monitor a patient'"'"'s arterial blood pressure and configured to be implanted subcutaneously, the device comprising:
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a housing; subcutaneous (SubQ) electrodes configured to obtain a subcutaneous electrocardiogram (SubQ ECG) that is indicative of electrical activity of the patient'"'"'s heart, the subQ electrodes are attached to the housing; a photoplethysmography (PPG) sensor configured to obtain a photoplethysmography (PPG) signal indicative of changes in the patient'"'"'s arterial blood volume, the PPG sensor comprising a light source and a light detector that are within, integral with or attached to the housing; an arterial blood pressure monitor, within the housing, configured to detect a predetermined feature of the SubQ ECG signal indicative of ventricular depolarization, detect a predetermined feature of the SubQ ECG signal indicative of ventricular repolarization, detect a predetermined feature of the PPG signal, and determine a time t1 from the predetermined feature of the SubQ ECG indicative of ventricular depolarization to the predetermined feature of the PPG signal, determine a time t2 from the predetermined feature of the SubQ ECG indicative of ventricular repolarization to the predetermined feature of the PPG signal, and determine at least one value indicative of the patient'"'"'s arterial blood pressure based on the times t1 and t2 determined from the SubQ ECG signal and PPG signal; wherein the implantable monitoring device is configured to transfer the at least one value indicative of the patient'"'"'s arterial blood pressure to an non-implanted device; wherein the implantable monitoring device is not configured to pace the patient'"'"'s heart and not configured to defibrillate the patient'"'"'s heart; and wherein the at least one value indicative of the patient'"'"'s arterial blood pressure is/are indicative of diastolic pressure (DP), systolic pressure (SP), pulse pressure (PP), mean arterial pressure (MAP), a change in DP, a change in SP, a change in PP and/or a change in MAP. - View Dependent Claims (25)
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26. A non-implantable monitoring device to monitor a patient'"'"'s arterial blood pressure, the device comprising:
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surface electrodes configured to obtain a surface electrocardiogram (ECG) that is indicative of electrical activity of the patient'"'"'s heart; a non-implantable plethysmography sensor configured to obtain a plethysmography signal indicative of changes in the patient'"'"'s arterial blood volume; an arterial blood pressure monitor configured to detect a predetermined feature of the surface ECG signal indicative of ventricular depolarization, detect a predetermined feature of the surface ECG signal indicative of ventricular repolarization, detect a predetermined feature of the plethysmography signal, determine a time t1 from the predetermined feature of the surface ECG indicative of ventricular depolarization to the predetermined feature of the plethysmography signal, determine a time t2 from the predetermined feature of the surface ECG indicative of ventricular repolarization to the predetermined feature of the plethysmography signal, and determine at least one value indicative of the patient'"'"'s arterial blood pressure based on the times t1 and t2 determined from the surface ECG signal and plethysmography signal. - View Dependent Claims (27, 28, 29)
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Specification