Method and apparatus for accommodating intraocular lens

• US 8,162,927 B2
• Filed: 07/25/2005
• Issued: 04/24/2012
• Est. Priority Date: 03/21/2000
• Status: Expired due to Fees

• Current Assignee: Gholam A. Peyman
• Original Assignee: Gholam A. Peyman
• Inventors: Peyman, Gholam A.
• Primary Examiner(s): SHAY, DAVID M
• Application Number:
  US11/189,044
• Publication Number:
  US 20060084949A1
• Time in Patent Office: 2,465 Days
• Field of Search: 606 4- 6, 606 10- 15, 623 611- 624, 623 627- 656, 623/6, 623/61
• US Class Current: 606/4
• CPC Class Codes: A61F 2/16 Intraocular lenses
• CPC Class Codes: A61F 2/1616 Pseudo-accommodative, e.g. multifocal or enabling monovision
• CPC Class Codes: A61F 2/1635 for changing shape
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61L 2430/16 for reconstruction of eye parts, e.g. intraocular lens, cornea
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: C08L 101/005 Dendritic macromolecules

Abstract

A method of replacing a natural lens in an eye is presented. The method includes removing the natural lens while leaving the capsular bag substantially intact, removing a portion of the capsular bag along the main optical axis, and placing biodendrimer within the capsular bag. Placing biodendrimer within the capsular bag can include placing a mixture of biodendrimer and at least one other material within the capsular bag. Biodendrimer can be approximately fifty percent of the mixture. The method can also include inserting an artificial bag within the capsular bag, injecting a synthetic material into the artificial bag to form an artificial lens, the synthetic material having loose monomers and a polymerization initiator so that the synthetic material changes its volume when exposed to an energy source, and selectively exposing portions of the artificial lens to an energy source to alter the refractive properties of the artificial lens.

Claims

1. A method of replacing a natural lens in an eye, comprising the steps of:

removing at least a portion of the natural lens while leaving the capsular bag substantially intact;

injecting a synthetic material into the capsular bag to form an artificial lens including loose monomers;

placing biodendrimer within the capsular bag; and

selectively exposing portions of the artificial lens to an energy source to alter the refractive properties of the artificial lens to change its volume to a predetermined volume to correct a predetermined refractive error when exposed to an energy source.

2. The method of claim 1, further comprising the step of:

removing a portion of the capsular bag along the main optical axis.

3. The method of claim 1, wherein placing biodendrimer within the capsular bag includes placing a mixture of biodendrimer and at least one other material within the artificial bag.

4. The method of claim 3, wherein biodendrimer is approximately fifty percent of the mixture.

5. The method of claim 1, further comprising the steps of:

inserting an artificial bag within the capsular bag; and

injecting the synthetic material into the artificial bag to form the artificial lens, the synthetic material having a polymerization initiator.

6. The method of claim 1, wherein the energy source is light.

7. The method of claim 5, wherein the step of placing biodendrimer within the capsular artificial bag includes injecting biodendrimer into the artificial bag.

8. The method of claim 5, wherein the step of placing biodendrimer within the capsular bag includes injecting biodendrimer between the artificial bag and the capsular bag.

9. The method of claim 5, wherein the artificial bag includes biodendrimer.

10. The method of claim 1, further comprising the step of:

exposing substantially the entire artificial lens to an energy source to polymerize substantially all of the loose monomers, thereby fixing the refractive power of the synthetic material.

11. The method of claim 5, wherein the step of inserting an artificial bag includes inserting an artificial bag having a first internal chamber and a second internal chamber.

12. The method of claim 11, wherein said first internal chamber includes a polymerized material, and said step of injecting a synthetic material into the artificial bag includes injecting said synthetic material into said second chamber.

13. The method of claim 12, wherein the polymerized material is biodendrimer.

14. The method of claim 12, wherein the step of placing biodendrimer within the capsular bag includes injecting biodendrimer into said second chamber.

15. The method of claim 5, wherein a portion of said artificial bag includes a polymerized material.

16. The method of claim 5, wherein the step of selectively exposing portions of the artificial lens to an energy source includes forming a multifocal lens.

17. The method of claim 1, further comprising the step of:

coating a portion of the capsular bag with a synthetic material, the synthetic material having loose monomers and a polymerization initiator so that the synthetic material changes its volume when exposed to an energy source.

18. The method of claim 17, wherein the step of placing biodendrimer within the capsular bag includes filling the remaining portion of the capsular bag with a material, wherein the material includes biodendrimer.

19. The method of claim 1, further comprising the step of:

inserting a lens into the capsular bag, the lens including loose monomers and a polymerization initiator so that the synthetic material changes the shape of the lens when the synthetic material is exposed to an energy source.

20. The method of claim 19, wherein the step of placing biodendrimer within the capsular bag includes filling the remaining portion of the capsular bag with a material, wherein the material includes biodendrimer.

21. A method of modifying the optical properties of an eye, comprising the steps of:

coating at least a portion of an external surface of a capsular bag with a synthetic substance, wherein the synthetic substance includes biodendrimer and an unpolymerized material positioned having loose monomers and a polymerization initiator so that the unpolymerized material changes the shape of the flexible capsule when exposed to an energy source.

22. An intraocular lens, comprising:

a flexible capsule adapted to be inserted into the natural lens capsular bag;

a polymerized portion, including biodendrimer, positioned within said flexible capsule; and

an unpolymerized material positioned within said flexible capsule, and having loose monomers and a polymerization initiator so that the unpolymerized material changes the shape of the flexible capsule when exposed to an energy source;

wherein said unpolymerized material is capable of changing the shape of the flexible capsule, such that the flexible capsule is multifocal.