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Subsystems and methods for use in patch clamp systems

  • US 8,163,147 B2
  • Filed: 12/04/2008
  • Issued: 04/24/2012
  • Est. Priority Date: 05/04/2007
  • Status: Active Grant
First Claim
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1. A method for determining a characteristic of a cell, the method comprising:

  • disconnecting clamping circuitry from a test head, the test head containing a cell;

    measuring, via sensing circuitry, a natural resting potential of the cell;

    storing the measured natural resting potential in memory;

    re-connecting the clamping circuitry to the test head;

    alternately applying to the cell, via the clamping circuitry, a first voltage substantially equal to the measured natural resting potential and a second voltage substantially equal to a sum of the measured natural resting potential and a step voltage; and

    measuring, via the clamping circuitry, a characteristic of the cell.

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