Systems for intraoperative nerve imaging
First Claim
Patent Images
1. A system for intraoperative nerve imaging during surgery, comprising:
- one or more illumination sources for producing a visible light and an excitation light, wherein the excitation light is configured to induce fluorescence in an agent that selectively binds to myelin basic protein applied to a surgical site;
an optical objective for directing the visible light and the excitation light in a direction of the surgical site and collecting visible light and fluorescent light emitted in at least two fluorescent emission channels from the surgical site;
a signal detector in operative association with the optical objective capable of detecting the visible light and fluorescent light; and
a signal processor for processing signals corresponding to the visible light and the fluorescent light emitted in at least two fluorescent emission channels from the surgical site.
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Accused Products
Abstract
Disclosed are systems for intraoperative nerve imaging using compact high collection power imaging devices for fluorescence and white light imaging of myelin basic protein (MBP) nerve imaging agents during open and minimally invasive surgery.
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Citations
20 Claims
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1. A system for intraoperative nerve imaging during surgery, comprising:
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one or more illumination sources for producing a visible light and an excitation light, wherein the excitation light is configured to induce fluorescence in an agent that selectively binds to myelin basic protein applied to a surgical site; an optical objective for directing the visible light and the excitation light in a direction of the surgical site and collecting visible light and fluorescent light emitted in at least two fluorescent emission channels from the surgical site; a signal detector in operative association with the optical objective capable of detecting the visible light and fluorescent light; and a signal processor for processing signals corresponding to the visible light and the fluorescent light emitted in at least two fluorescent emission channels from the surgical site. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification