Method and system for overdriving a heart chamber during a threshold search according to an AV delay

• US 8,170,671 B2
• Filed: 06/12/2009
• Issued: 05/01/2012
• Est. Priority Date: 06/12/2009
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Sloman, Laurence S., Snell, Jeffery D.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): SARCIONE, JESSICA LYNN
• Application Number:
  US12/483,976
• Publication Number:
  US 20100318152A1
• Time in Patent Office: 1,054 Days
• Field of Search: 607 27- 28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3682 with a variable atrioventricular delay
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

An implantable medical device includes a lead, a pulse generator, an autothreshold module and a control module. The lead includes electrodes positioned within a heart. At least one of the electrodes senses cardiac signals. The pulse generator delivers a stimulus pulse through at least one of the electrodes. The autothreshold module performs a threshold search when operating in an autothreshold mode and causes atrial stimulus pulses to be delivered in an atrium of the heart at an overdrive rate during the threshold search. The control module determines an AV conduction time and applies an overdrive AV adjustment to the AV conduction time to generate an AV delay. The autothreshold module uses the AV delay in connection with delivering ventricular stimulus pulses to a ventricle of the heart.

Claims

1. An implantable medical device comprising:

a lead including electrodes configured to be positioned within a heart, at least one of the electrodes being capable of sensing cardiac signals;

a pulse generator to deliver a stimulus pulse through at least one of the electrodes;

an autothreshold module to perform a threshold search when operating in an autothreshold mode, the autothreshold module to cause atrial stimulus pulses to be delivered in an atrium of the heart at an overdrive rate during the threshold search; and

a control module to determine an AV conduction time and to apply an overdrive AV adjustment to the AV conduction time to generate an AV delay, the autothreshold module to utilize the AV delay in connection with delivering ventricular stimulus pulses to a ventricle of the heart, wherein the control module measures the AV conduction time between atrial stimulus pulses while the autothreshold module is in the autothreshold mode.

2. The implantable medical device of claim 1, wherein the overdrive AV adjustment is predetermined and the control module shortens or lengthens the AV conduction time by the overdrive AV adjustment to generate the AV delay.

3. The implantable medical device of claim 1, wherein the control module measures the AV conduction time while the autothreshold module causes the atrial stimulus pulses to be delivered, and the control module calculates the overdrive AV adjustment based on the AV conduction time.

4. The implantable medical device of claim 1, wherein the control module measures cardiac signals over multiple cardiac cycles and calculates a cardiac rate based thereon, the control module determining the overdrive rate as a function of the cardiac rate.

5. The implantable medical device of claim 1, wherein the autothreshold module enters the autothreshold mode when a loss of capture is detected in at least two consecutive cardiac cycles.

6. The implantable medical device of claim 1, wherein the autothreshold module applies the atrial stimulation pulses and the ventricular stimulation pulses separated from one another by the AV delay.

7. The implantable medical device of claim 1, wherein the AV conduction time represents an elapsed time between applying the stimulus pulse to the atrium and a contraction in the ventricle.

8. The implantable medical device of claim 1, wherein the autothreshold module adjusts the atrial stimulus pulses during the threshold search.

9. A method for overdriving a heart chamber during a threshold search, the method comprising:

delivering stimulus pulses to an atrium of the heart at an overdrive rate during the threshold search;

determining an AV conduction time based on the stimulation pulses;

applying an overdrive AV adjustment to the AV conduction time to generate an AV delay; and

utilizing the AV delay in connection with delivering a stimulus pulse to a ventricle of the heart, wherein the determining operation comprises measuring the AV conduction time between stimulation pulses.

10. The method of claim 9, wherein the overdrive AV adjustment is predetermined and the applying operation comprises shortening or lengthening the AV conduction time by the overdrive AV adjustment to generate the AV delay.

11. The method of claim 9, wherein determining operation comprises measuring the AV conduction time while the delivering operation delivers the stimulation pulse, further wherein the applying operation comprises calculating the overdrive AV adjustment based on the AV conduction time.

12. The method of claim 9, further comprising measuring cardiac signals over multiple cardiac cycles, calculating a cardiac rate based thereon, and determining the overdrive rate as a function of the cardiac rate.

13. The method of claim 9, wherein the autothreshold module enters the autothreshold mode when a loss of capture is detected in at least two consecutive cardiac cycles.

14. The method of claim 9, wherein the atrial stimulation pulses and the ventricular stimulation pulses are delivered such that each atrial stimulation pulse is separated from each subsequent ventricular stimulation pulse by the AV delay.

15. The method of claim 9, wherein the AV conduction time represents an elapsed time between applying the stimulus pulse to the atrium and a contraction in the ventricle.

16. A non-transitory computer readable storage medium for use with an implantable medical device having a lead including electrodes configured to be positioned within a heart, a pulse generator and a microcontroller, the computer readable storage medium comprising instructions to:

direct the pulse generator to deliver atrial stimulus pulses in an atrium of the heart at an overdrive rate during a threshold search; and

direct the microcontroller to;

determine an AV conduction time; and

apply an overdrive AV adjustment to the AV conduction time to generate an AV delay,

wherein the instructions direct the pulse generator to utilize the AV delay in connection with delivering ventricular stimulus pulses to a ventricle of the heart, wherein the instructions direct the microcontroller to measure the AV conduction time between atrial stimulus pulses during the threshold search.

17. The computer readable storage medium of claim 16, wherein the overdrive AV adjustment is predetermined and the instructions direct the microcontroller to shorten or lengthen the AV conduction time by the overdrive AV adjustment to generate the AV delay.

18. The computer readable storage medium of claim 16, wherein the instructions direct the microcontroller to measure the AV conduction time while directing the pulse generator to deliver the atrial stimulus pulses, further wherein the instructions direct the microcontroller to calculate the overdrive AV adjustment based on the AV conduction time.

19. The computer readable storage medium of claim 16, wherein the instructions direct the microcontroller to measure cardiac signals over multiple cardiac cycles and calculate a cardiac rate based thereon to determine the overdrive rate as a function of the cardiac rate.

20. The computer readable storage medium of claim 16, wherein the instructions direct the microcontroller to initiate the threshold search when a loss of capture is detected in at least two consecutive cardiac cycles.

21. The computer readable storage medium of claim 16, wherein the instructions direct the pulse generator to apply the atrial stimulation pulses and the ventricular stimulation pulses separated from one another by the AV delay.

22. The computer readable storage medium of claim 16, wherein the AV conduction time represents an elapsed time between applying the stimulus pulse to the atrium and a contraction in the ventricle.