Methods and systems for detecting epileptic events using nonlinear analysis parameters
First Claim
Patent Images
1. A method comprising:
- receiving data relating to a beat sequence of a patient'"'"'s heart;
determining at least one regularity nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart and at least one predictability nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart;
performing a first comparison of the at least one regularity nonlinear analysis parameter to a first adjustable threshold;
performing a second comparison of the at least one predictability nonlinear analysis parameter to a second adjustable threshold;
detecting an epilepsy event based on the first comparison and the second comparison, the epilepsy event comprising at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and
providing an output indicative of the epilepsy event.
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Abstract
Disclosed herein are methods, systems, and apparatus for detecting an epilepsy event in a patient using a medical device. The medical device is capable of determining an occurring epilepsy event, for example a seizure or an increased risk of a seizure. The determination is performed by determining at least one nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart. The medical device may then take a responsive action, such as warning, logging the time of the seizure, computing and storing one or more seizure severity indices, and treating the epilepsy event.
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Citations
32 Claims
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1. A method comprising:
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receiving data relating to a beat sequence of a patient'"'"'s heart; determining at least one regularity nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart and at least one predictability nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart; performing a first comparison of the at least one regularity nonlinear analysis parameter to a first adjustable threshold; performing a second comparison of the at least one predictability nonlinear analysis parameter to a second adjustable threshold; detecting an epilepsy event based on the first comparison and the second comparison, the epilepsy event comprising at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and providing an output indicative of the epilepsy event. - View Dependent Claims (2)
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3. A method comprising:
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receiving data relating to a beat sequence of a patient'"'"'s heart; determining at least one regularity nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart; performing a comparison of the at least one regularity nonlinear analysis parameter to an adjustable threshold; detecting an epilepsy event based on the comparison, the epilepsy event comprising at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and providing an output indicative of the epilepsy event. - View Dependent Claims (4)
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5. A method comprising:
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receiving data relating to a beat sequence of a patient'"'"'s heart; determining at least one predictability nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart; performing a comparison of the at least one predictability nonlinear analysis parameter to an adjustable threshold; detecting an epilepsy event based on the comparison, the epilepsy event comprising at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and providing an output indicative of the epilepsy event. - View Dependent Claims (6)
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7. A method comprising:
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receiving data relating to a beat sequence of a patient'"'"'s heart; determining at least one nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart; performing a comparison of the at least one nonlinear analysis parameter to an adjustable threshold; detecting an epilepsy event based on the comparison, the epilepsy event comprising at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and providing an output indicative of the epilepsy event. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14)
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15. A medical device comprising:
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a sensing module adapted to receive data relating to a beat sequence of a patient'"'"'s heart; a nonlinear analysis parameter processing module adapted to determine at least one nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart, adapted to perform a comparison of the at least one nonlinear analysis parameter to an adjustable threshold, and adapted to detect an epilepsy event based on the comparison, the epilepsy event including at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and a communication unit adapted to provide an output indicative of the epilepsy event. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22)
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23. A computer readable program storage device encoded with instructions that, when executed by a processor, cause the processor to:
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receive data relating to a beat sequence of a patient'"'"'s heart; determine at least one nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart; perform a comparison of the at least one nonlinear analysis parameter to an adjustable threshold; detect an epilepsy event based on the comparison, the epilepsy event comprising at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and provide an output indicative of the epilepsy event. - View Dependent Claims (24, 25, 26)
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27. A medical system comprising:
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a sensing module adapted to receive data related to a beat sequence of a patient'"'"'s heart; a nonlinear analysis parameter processing module adapted to determine at least one nonlinear analysis parameter associated with the beat sequence of the patient'"'"'s heart, to perform a comparison of the at least one nonlinear analysis parameter to an adjustable threshold, and to detect an epilepsy event based on the comparison, the epilepsy event comprising at least one of an unstable brain state, a brain state indicative of an elevated probability of a seizure, a brain state indicative of an impending seizure, and a seizure; and a storage unit to store an indication of the epilepsy event. - View Dependent Claims (28, 29, 30, 31, 32)
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Specification