Measurement system with optical referencing
First Claim
1. A system for determining the concentration of an analyte in a liquid by absorption measurement, comprising a test element with a detection area which comprises at least one reaction area with reagents for detecting the analyte which cause a change in the absorption behavior in the reaction area upon reaction with the analyte, the detection area further comprising at least one reference area, the system further comprising a detection unit for the spatially resolved detection of light intensities which are received at least from a part of the detection area, and an evaluation unit for evaluating signals of the detection unit;
- wherein the one or more reference areas are configured such that the absorption behavior does not substantially change upon wetting with the liquid having the analyte.
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Accused Products
Abstract
A system is described for determining the concentration of an analyte in a liquid by absorption measurement comprising a test element with a detection area which contains at least one reaction area with reagents for detecting the analyte which cause a change in the absorption behavior upon reaction with the analyte. The detection area contains at least one reference area in which the absorption behavior is substantially not changed when wetted by a sample having the analyte. Furthermore, the system contains a detection unit for the spatially resolved detection of light intensities which are received from the detection area and an evaluation unit for evaluating signals from the detection unit. Further embodiments of the system comprise reaction areas and reference areas arranged alternately in two dimensions.
26 Citations
24 Claims
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1. A system for determining the concentration of an analyte in a liquid by absorption measurement, comprising a test element with a detection area which comprises at least one reaction area with reagents for detecting the analyte which cause a change in the absorption behavior in the reaction area upon reaction with the analyte, the detection area further comprising at least one reference area, the system further comprising a detection unit for the spatially resolved detection of light intensities which are received at least from a part of the detection area, and an evaluation unit for evaluating signals of the detection unit;
- wherein the one or more reference areas are configured such that the absorption behavior does not substantially change upon wetting with the liquid having the analyte.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A test element for determining the concentration of an analyte in a body fluid by determining the optical density, comprising a detection area which contains a plurality of reaction areas including reagents and a plurality of reference areas;
- wherein the reference areas are configured such that the optical density of each is substantially not changed when wetted by the body fluid having the analyte.
- View Dependent Claims (14, 23, 24)
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15. A method for producing a test element for determining an analyte in a body fluid by measurement of an absorption behavior, comprising the steps of providing a support material, and applying a detection area on at least a portion of the support material, the detection area comprising at least one reaction area and at least one reference area;
- wherein applying the detection area includes applying one or more reagents for detecting the analyte on the portion of the support material, said reagents for causing a change in the absorption behavior when wetted by the body fluid having the analyte; and
wherein the one or more reference areas are configured such that the absorption behavior of each is substantially not changed when wetted by the body fluid having the analyte. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22)
- wherein applying the detection area includes applying one or more reagents for detecting the analyte on the portion of the support material, said reagents for causing a change in the absorption behavior when wetted by the body fluid having the analyte; and
Specification