Apparatus and method for measuring oxygen saturation in blood

• US 8,175,669 B2
• Filed: 08/24/2006
• Issued: 05/08/2012
• Est. Priority Date: 08/24/2005
• Status: Active Grant

• Current Assignee: Nihon Kohden Corporation
• Original Assignee: Nihon Kohden Corporation
• Inventors: Kobayashi, Naoki, Miyata, Kenji, Yarita, Masaru, Ito, Kazumasa
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Fardanesh, Marjan
• Application Number:
  US11/508,995
• Publication Number:
  US 20070049811A1
• Time in Patent Office: 2,084 Days
• Field of Search: 600309-344
• US Class Current: 600/336
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7257 using Fourier transforms

Abstract

In an apparatus for measuring an oxygen saturation in blood, a plurality of light emitters irradiate a living tissue with a plurality of light beams having different wavelengths. A light receiver receives the light beams reflected from or transmitted through the living tissue to generate pulse wave signals in accordance with pulsations of the blood in the living tissue. A separator separates each of the pulse wave signals into a plurality of amplitude signals each of which is associated with one frequency, thereby generating pairs of amplitude signals each of which is associated with one of a plurality of frequencies. A first processor calculates a ratio between the amplitude signals in each of the pairs of the amplitude signals. A selector selects one of the pairs of the amplitude signals. A second processor calculates the oxygen saturation from the ratio of the selected pair of the amplitude signals.

Claims

1. An apparatus for measuring an oxygen saturation in blood, comprising:

a plurality of light emitters, adapted to irradiate a living tissue with a plurality of light beams having different wavelengths;

a light receiver, adapted to receive the light beams reflected from or transmitted through the living tissue to generate pulse wave signals in accordance with pulsations of the blood in the living tissue;

a separator, operable to separate each of the pulse wave signals into a plurality of amplitude signals each of which is associated with one frequency, thereby generating pairs of amplitude signals each of which is associated with one of a plurality of frequencies;

a first processor, operable to calculate a ratio between the amplitude signals in each of the pairs of the amplitude signals;

a selector, which is operable to select one of the pairs of the amplitude signals based on the amplitude values of the amplitude signals, wherein the selector selects a pair of the amplitude signals that have maximum amplitude values; and

a second processor, operable to calculate the oxygen saturation based on the ratio of the selected one of the pairs of the amplitude signals.

2. The apparatus as set forth in claim 1, wherein:

the separator comprises either an FFT processor or a digital filter.

3. The apparatus as set forth in claim 1, wherein:

the selector is operable to select either such a pair of the amplitude signals that have maximum amplitude values or such a pair of the amplitude signals that the ratio takes a minimum value in accordance with a prescribed condition.

4. The apparatus as set forth in claim 3, wherein:

the prescribed condition includes a waveform of the amplitude signals.

5. The apparatus as set forth in claim 1, wherein the light beams include a red light beam and an infrared light beam.

6. A method for measuring an oxygen saturation in blood, comprising:

irradiating a living tissue with a plurality of light beams having different wavelengths;

receiving the light beams reflected from or transmitted through the living tissue to generate pulse wave signals in accordance with pulsations of the blood in the living tissue;

separating each of the pulse wave signals into a plurality of amplitude signals each of which is associated with one frequency, thereby generating pairs of amplitude signals each of which is associated with one of a plurality of frequencies;

calculating a ratio between the amplitude signals in each of the pairs of the amplitude signals;

selecting one of the pairs of the amplitude signals based on the amplitude values of the amplitude signals; and

calculating the oxygen saturation based on the ratio of the selected one of the pairs of the amplitude signals,

wherein a pair of the amplitude signals that have maximum amplitude values is selected as the selected one of the pairs of the amplitude signals.

7. The method as set forth in claim 6, wherein:

the separating is performed with either an FFT processing or a digital filtering.

8. The method as set forth in claim 6, wherein:

either such a pair of the amplitude signals that have maximum amplitude values or such a pair of the amplitude signals that the ratio takes a minimum value is selected as the one of the pairs of the amplitude signals in accordance with a prescribed condition.

9. The method as set forth in claim 8, wherein:

the prescribed condition includes a waveform of the amplitude signals.

10. An apparatus for measuring an oxygen saturation in blood, comprising:

a plurality of light emitters, adapted to irradiate a living tissue with a plurality of light beams having different wavelengths;

a light receiver, adapted to receive the light beams reflected from or transmitted through the living tissue to generate pulse wave signals in accordance with pulsations of the blood in the living tissue;

a separator, operable to separate each of the pulse wave signals into a plurality of amplitude signals each of which is associated with one frequency, thereby generating pairs of amplitude signals each of which is associated with one of a plurality of frequencies;

a first processor, operable to calculate a ratio between the amplitude signals in each of the pairs of the amplitude signals;

a selector, which is operable to select one of the pairs of the amplitude signals based on the amplitude values of the amplitude signals, wherein the selector selects a pair of the amplitude signals that the ratio between the amplitude signales takes a minimum value; and

a second processor, operable to calculate the oxygen saturation based on the ratio of the selected one of the pairs of the amplitude signals.

11. The apparatus as set forth in claim 10, wherein:

the first processor comprises;

a first calculator, operable to define a plurality of frequency bands each of which includes a plurality of amplitude signals obtained from each of the pulse wave signals, and operable to calculate an average value of the amplitude signals in each of the frequency bands, thereby generating pairs of average values each of which is associated with one of the frequency bands; and

a second calculator, operable to calculate an average ratio between the average values in each of the pairs of the average values; and

the selector is operable to select such a frequency band that the average ratio takes a minimum value.

12. The apparatus as set forth in claim 11, wherein:

a part of one of the frequency bands is overlapped with a part of another one of the frequency bands.

13. The apparatus as set forth in claim 10, wherein:

the first processor comprises;

a first calculator, operable to;

define a plurality of frequency bands each of which includes a plurality of amplitude signals obtained from each of the pulse wave signals;

judge whether there is a maximal point of the amplitude signals in each of the frequency bands; and

calculate an average value of the amplitude signals in at least one of the frequency bands which is judged as one including the maximal point, thereby at least one pair of average values each of which is associated with one of the frequency bands; and

a second calculator, operable to calculate an average ratio between the average values in each of the at least one pair of the average values; and

the selector is operable to select such a frequency band that the average ratio takes a minimum value.

14. The apparatus as set forth in claim 13, wherein:

a part of one of the frequency bands is overlapped with a part of another one of the frequency bands.

15. The apparatus as set forth in 10, wherein:

the first processor comprises;

a first calculator, operable to calculate ratios each of which is a ratio between each of the pairs of the amplitude signals; and

a second calculator, operable to define a plurality of frequency bands each of which includes a plurality of amplitude signals obtained from each of the pulse wave signals, and operable to calculate an average value of the ratios in each of the frequency bands, thereby generating a plurality of average values; and

the selector is operable to select such a frequency band that the average value takes a minimum value.

16. The apparatus as set forth in claim 15, wherein:

a part of one of the frequency bands is overlapped with a part of another one of the frequency bands.

17. A method for measuring an oxygen saturation in blood, comprising:

irradiating a living tissue with a plurality of light beams having different wavelengths;

receiving the light beams reflected from or transmitted through the living tissue to generate pulse wave signals in accordance with pulsations of the blood in the living tissue;

separating each of the pulse wave signals into a plurality of amplitude signals each of which is associated with one frequency, thereby generating pairs of amplitude signals each of which is associated with one of a plurality of frequencies;

calculating a ratio between the amplitude signals in each of the pairs of the amplitude signals;

selecting one of the pairs of the amplitude signals based on the amplitude values of the amplitude signals; and

calculating the oxygen saturation based on the ratio of the selected one of the pairs of the amplitude signals,

wherein a pair of the amplitude signals that the ratio takes a minimum value is selected as the selected one of the pairs of the amplitude signals.

20. The method as set forth in claim 17, further comprising:

defining a plurality of frequency bands each of which includes a plurality of amplitude signals obtained from each of the pulse wave signals;

judging whether there is a maximal point of the amplitude signals in each of the frequency bands;

calculating an average value of the amplitude signals in at least one of the frequency bands which is judged as one including the maximal point, thereby at least one pair of average values each of which is associated with one of the frequency bands;

calculating an average ratio between the average values in each of the at least one pair of the average values; and

selecting such a frequency band that the average ratio takes a minimum value.

21. The method as set forth in claim 20, wherein:

a part of one of the frequency bands is overlapped with a part of another one of the frequency bands.

22. The method as set forth in claim 17;

further comprising;

calculating ratios each of which is a ratio between each of the pairs of the amplitude signals;

defining a plurality of frequency bands each of which includes a plurality of amplitude signals obtained from each of the pulse wave signals;

calculating an average value of the ratios in each of the frequency bands, thereby generating a plurality of average values; and

selecting such a frequency band that the average value takes a minimum value.

23. The method as set forth in claim 22, wherein:

a part of one of the frequency bands is overlapped with a part of another one of the frequency bands.

18. The method as set forth in claim l7, further comprising:

defining a plurality of frequency bands each of which includes a plurality of amplitude signals obtained from each of the pulse wave signals;

calculating an average value of the amplitude signals in each of the frequency bands, thereby generating pairs of average values each of which is associated with one of the frequency bands;

calculating an average ratio between the average values in each of the pairs of the average values; and

selecting such a frequency band that the average ratio takes a minimum value.

19. The method as set forth in claim 18, wherein:

a part of one of the frequency bands is overlapped with a part of another one of the frequency bands.

24. An apparatus for measuring an oxygen saturation in blood, comprising:

a plurality of light emitters, adapted to irradiate a living tissue with a plurality of light beams having different wavelengths;

a light receiver, adapted to receive the light beams reflected from or transmitted through the living tissue to generate pulse wave signals in accordance with pulsations of the blood in the living tissue;

a separator, operable to separate each of the pulse wave signals into a plurality of amplitude signals each of which is associated with one frequency, thereby generating pairs of amplitude signals each of which is associated with one of a plurality of frequencies;

a first processor, operable to calculate a ratio between the amplitude signals in each of the pairs of the amplitude signals;

a selector, which is operable to select one of the pairs of the amplitude signals based on the amplitude values of the amplitude signals, wherein the selector selects either a pair of the amplitude signals that have maximum amplitude values or a pair of the amplitude signals that the ratio takes a minimum value in accordance with a prescribed condition; and

a second processor, operable to calculate the oxygen saturation based on the ratio of the selected one of the pairs of the amplitude signals.

25. A method for measuring an oxygen saturation in blood, comprising:

irradiating a living tissue with a plurality of light beams having different wavelengths;

receiving the light beams reflected from or transmitted through the living tissue to generate pulse wave signals in accordance with pulsations of the blood in the living tissue;

separating each of the pulse wave signals into a plurality of amplitude signals each of which is associated with one frequency, thereby generating pairs of amplitude signals each of which is associated with one of a plurality of frequencies;

calculating a ratio between the amplitude signals in each of the pairs of the amplitude signals;

selecting one of the pairs of the amplitude signals based on the amplitude values of the amplitude signals; and

calculating the oxygen saturation based on the ratio of the selected one of the pairs of the amplitude signals,

wherein either a pair of the amplitude signals that have maximum amplitude values or a pair of the amplitude signals that the ratio takes a minimum value is selected as the selected one of the pairs of the amplitude signals in accordance with a prescribed condition.