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Method for reversible chemical modulation of neural activity

  • US 8,180,447 B2
  • Filed: 06/18/2008
  • Issued: 05/15/2012
  • Est. Priority Date: 12/05/2007
  • Status: Expired due to Fees
First Claim
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1. A method of modulating neural activity comprising the steps of:

  • producing a reversible conduction block in a peripheral neural structure of a subject with a chemical blocking agent while the subject is in a low activity state;

    reversing the reversible conduction block in the peripheral neural structure of the subject to permit conduction in the peripheral neural structure when the subject is in a higher activity state by applying a reversing stimulus configured to counter the chemical blocking agent used to produce the reversible conduction block in the peripheral neural structure of the subject; and

    repeating the steps of producing a reversible conduction block in a peripheral neural structure of a subject while the subject is in a low activity state and reversing the reversible conduction block in the peripheral neural structure of the subject to permit conduction in the peripheral neural structure when the subject is in a higher activity state.

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