Orthovoltage radiosurgery
First Claim
1. A method of treating tissue at a target zone deep to a surface of a patient'"'"'s body by emitting, from an x-ray source having a system axis defined in a global coordinate system, a collimated x-ray beam having a beam axis defined in the global coordinate system, said method comprising:
- (a) determining a reference axis defined relative to the patient'"'"'s body, the reference axis being in the global coordinate system;
(b) determining a treatment axis that intersects the target zone, the treatment axis being in the global coordinate system;
(c) positioning the x-ray source at a first position with respect to the system axis, such that the beam axis intersects the treatment axis at a first treatment site within the target zone and such that the beam axis intersects the surface of the patient'"'"'s body at a first location;
(d) emitting an x-ray beam toward the target zone along the beam axis, to irradiate the target zone with a first radiation dose;
(e) rotating the x-ray source about the system axis to a second position with respect to the system axis, such that the beam axis intersects the treatment axis at a second treatment site within the target zone and such that the beam axis intersects the surface of the patient'"'"'s body at a second location that is separated from the first location by a first distance; and
(f) emitting an x-ray beam toward the target zone along the beam axis, to irradiate the target zone with a second radiation dose.
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Accused Products
Abstract
A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. Some embodiments provide that, among other targets, ocular structures are treated. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
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Citations
35 Claims
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1. A method of treating tissue at a target zone deep to a surface of a patient'"'"'s body by emitting, from an x-ray source having a system axis defined in a global coordinate system, a collimated x-ray beam having a beam axis defined in the global coordinate system, said method comprising:
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(a) determining a reference axis defined relative to the patient'"'"'s body, the reference axis being in the global coordinate system; (b) determining a treatment axis that intersects the target zone, the treatment axis being in the global coordinate system; (c) positioning the x-ray source at a first position with respect to the system axis, such that the beam axis intersects the treatment axis at a first treatment site within the target zone and such that the beam axis intersects the surface of the patient'"'"'s body at a first location; (d) emitting an x-ray beam toward the target zone along the beam axis, to irradiate the target zone with a first radiation dose; (e) rotating the x-ray source about the system axis to a second position with respect to the system axis, such that the beam axis intersects the treatment axis at a second treatment site within the target zone and such that the beam axis intersects the surface of the patient'"'"'s body at a second location that is separated from the first location by a first distance; and (f) emitting an x-ray beam toward the target zone along the beam axis, to irradiate the target zone with a second radiation dose. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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28. An x-ray treatment system for treating tissue at a target zone, deep to a surface of a patient'"'"'s body, by emission of a collimated x-ray beam, the system comprising:
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(a) an alignment assembly operative to determine a reference axis defined relative to the patient'"'"'s body, which axis has a position and orientation in a global coordinate system; (b) an x-ray source positionable in relation to a system axis defined in the global coordinate system, and operative to emit a collimated x-ray beam having a beam axis defining a beam path; and (c) a control unit operatively connected to the alignment assembly and x-ray source, the control unit operating to; (c
1) determine, from information received from the alignment assembly related to an anatomical representation of the body, a treatment axis in the global coordinate system;(c2) direct the x-ray source to move to a first position with respect to the system axis, at which the beam axis intersects the treatment axis at the target zone at an incident angle with respect to the treatment axis, such that the beam axis intersects a surface of the body at a first position; (c3) direct the x-ray source to emit the x-ray beam toward the target zone along the beam axis, to irradiate the target zone with a radiation dose; (c4) direct the x-ray source to move with respect to the system axis to a second position, at which the beam axis intersects the treatment axis at the target zone at an incident angle with respect to the treatment axis, so that the beam axis intersects the surface of the body at a second position, different from the first position; and (c5) direct the x-ray source to emit the x-ray beam toward the target zone along the beam axis, to irradiate the target zone with a radiation dose. - View Dependent Claims (29, 30, 31, 32, 33, 34, 35)
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Specification