Deformable 2D-3D registration

• US 8,184,886 B2
• Filed: 08/15/2008
• Issued: 05/22/2012
• Est. Priority Date: 08/21/2007
• Status: Active Grant

• Current Assignee: Siemens Healthineers AG (Siemens AG)
• Original Assignee: Siemens AG
• Inventors: Khamene, Ali, Fluck, Oliver, Aharon, Shmuel
• Primary Examiner(s): Johns, Andrew W
• Application Number:
  US12/192,278
• Publication Number:
  US 20090052757A1
• Time in Patent Office: 1,376 Days
• Field of Search: 382/107, 382/128, 382/131, 382/132, 382/154, 382/294
• US Class Current: 382/131
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/5229 combining image data of a patient, e.g. combining a functional image with an anatomical image
• CPC Class Codes: A61B 6/5235 combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
• CPC Class Codes: A61N 2005/1062 using virtual X-ray images, e.g. digitally reconstructed radiographs [DRR]
• CPC Class Codes: A61N 5/103 Treatment planning systems
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/10124 Digitally reconstructed radiograph [DRR]
• CPC Class Codes: G06T 2207/30004 Biomedical image processing
• CPC Class Codes: G06T 7/30 Determination of transform parameters for the alignment of images, i.e. image registration
• CPC Class Codes: G06V 20/647 by matching two-dimensional images to three-dimensional objects

Abstract

A method for deformable registration including determining a vector field from a two-dimensional matching of a volume of an object of interest and a two-dimensional image of the object of interest, providing a deformation profile, and finding a volume deformation that maps to a state of the two-dimensional image, wherein the deformation is parameterized by the vector field and control points of the deformation profile to find a control point configuration of the volume deformation.

Claims

1. A computer implemented method for deformable registration comprising:

determining a vector field from a two-dimensional matching of a simulated two-dimensional image of a volume of an object of interest and a two-dimensional image of the object of interest;

providing a deformation profile comprising control points representing movement of the object of interest over time; and

finding a volume deformation that maps to a state of the two-dimensional image, wherein the deformation is parameterized by the vector field and the control points of the deformation profile to update a control point configuration of the simulated two-dimensional image of the volume of the object of interest.

2. The computer implemented method of claim 1, wherein the vector field maps differences between the simulated two-dimensional image of the volume of the object of interest and the two-dimensional image of the object of interest.

3. The computer implemented method of claim 1, wherein finding the volume deformation comprises:

a two-dimensional to three-dimensional back projection mapping the vector field to the deformation profile with respect to perspective distortion; and

generating a simulated three-dimensional deformation.

4. The computer implemented method of claim 3, further comprising a deformation for generating the simulated two-dimensional image of the volume of the object of interest from the simulated three-dimensional deformation.

5. A non-transitory computer readable medium embodying instructions executable by a processor to perform a method for deformable registration comprising:

determining a vector field from a two-dimensional matching of a simulated two-dimensional image of a volume of an object of interest and a two-dimensional image of the object of interest;

providing a deformation profile comprising control points representing movement of the object of interest over time; and

finding a volume deformation that maps to a state of the two-dimensional image,

wherein the deformation is parameterized by the vector field and the control points of the deformation profile to update a control point configuration of the simulated two-dimensional image of the volume of the object of interest.

6. The computer readable medium of claim 5, wherein the vector field maps differences between the simulated two-dimensional image of the volume of the object of interest and the two-dimensional image of the object of interest.

7. The computer readable medium of claim 5, wherein finding the volume deformation comprises:

a two-dimensional to three-dimensional back projection mapping the vector field to the deformation profile with respect to perspective distortion; and

generating a simulated three-dimensional deformation.

8. The computer readable medium of claim 7, further comprising a deformation for generating the simulated two-dimensional image of the volume of the object of interest from the simulated three-dimensional deformation.

9. A method for deformable registration comprising:

capturing a volumetric data set representing a patent by a first imaging modality;

capturing a two-dimensional image representing the patient by a second imaging modality;

determining a vector field from a two-dimensional matching of a simulated two-dimensional image of the volumetric data set and the two-dimensional image;

providing a deformation profile comprising control points representing movement of the patient over time; and

finding a volume deformation that maps to a state of the two-dimensional image,

wherein the deformation is parameterized by the vector field and the control points of the deformation profile to update a control point configuration of the simulated two-dimensional image of the volumetric data set, and

wherein the simulated two-dimensional image updated by the control point configuration is displayed.

10. The computer implemented method of claim 9, wherein the vector field maps differences between the simulated two-dimensional image of the volumetric data set and the two-dimensional image.

11. The computer implemented method of claim 9, wherein finding the volume deformation comprises:

a two-dimensional to three-dimensional back projection mapping the vector field to the deformation profile with respect to perspective distortion; and

generating a simulated three-dimensional deformation.

12. The computer implemented method of claim 11, further comprising a deformation for generating the simulated two-dimensional image of the volumetric data set from the simulated three-dimensional deformation.