Method and apparatus to detect and monitor the frequency of obstructive sleep apnea

• US 8,187,200 B2
• Filed: 02/12/2009
• Issued: 05/29/2012
• Est. Priority Date: 04/30/2002
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Jensen, Donald N., Condie, Catherine R., Cho, Yong Kyun
• Primary Examiner(s): Schaetzle, Kennedy
• Assistant Examiner(s): LEE, ERICA SHENGKAI
• Application Number:
  US12/369,899
• Publication Number:
  US 20090209880A1
• Time in Patent Office: 1,202 Days
• Field of Search: 600/529, 600532-534, 600/536, 600/547, 607/17
• US Class Current: 600/534
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61B 5/1118 Determining activity level
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/4818 Sleep apnoea

Abstract

The present invention provides a method and apparatus for detecting and monitoring obstructive sleep apnea. The apparatus includes an intracardiac impedance sensor to measure intracardiac impedance, a movement sensor to measure an amount of movement of a patient, and a controller operatively coupled to said intracardiac impedance sensor and said movement sensor, said controller adapted to receive at least one of an intracardiac impedance and the amount of movement of the patient and detect obstructive sleep apnea based upon said intracardiac impedance and said movement.

Claims

1. A method of detecting and monitoring obstructive sleep apnea, comprising:

measuring impedance minute ventilation to detect a change in the impedance minute ventilation corresponding to a period of hyperpneic respiration, wherein the change includes an increase in impedance minute ventilation followed by a decrease in impedance minute ventilation;

detecting an increasing amount of movement of a patient during the period of hyperpneic respiration; and

determining the presence of obstructive sleep apnea responsive to the change in the impedance minute ventilation coinciding with the increasing movement of the patient.

2. A method of claim 1, wherein measuring impedance minute ventilation further comprises detecting a rapid change in the increase in impedance minute ventilation followed by a gradual change in the decrease in impedance minute ventilation.

3. A method of claim 1, wherein measuring the increasing amount of movement of the patient further comprises detecting an amount of movement of the patient from a state corresponding to a state of physical inactivity of the patient.

5. The method of claim 1, further comprising:

correlating a decrease in intrathoracic impedance during an attempted inspiration of the patient with the presence of obstructive sleep apnea.

6. The method of claim 1, wherein the impedance minute ventilation is measured between an electrode in an atrium of a heart and an electrode in a ventricle of a heart.

7. The method of claim 1, wherein the impedance minute ventilation is measured between an implantable device housing and an endocardial electrode.

8. The method of claim 5, further comprising detecting an arousal of a patient from sleep coinciding with the occurrence of the attempted inspiration.

9. The method of claim 8, further comprising determining an occurrence of obstructive sleep apnea in response to detecting the occurrence of the attempted inspiration of the patient coinciding with detection of arousal of the patient from sleep.

4. A medical device for detecting and monitoring obstructive sleep apnea, comprising:

means for measuring impedance minute ventilation to detect a change in the impedance minute ventilation corresponding to a period of hyperpneic respiration, wherein the change includes an increase in impedance minute ventilation followed by a decrease in impedance minute ventilation;

means for detecting an increasing amount of movement of a patient during the period of hyperpneic respiration; and

means for determining the presence of obstructive sleep apnea responsive to the change in the impedance minute ventilation coinciding with the increasing movement of the patient.