Safety vent structure for extracorporeal circuit

• US 8,187,466 B2
• Filed: 05/05/2011
• Issued: 05/29/2012
• Est. Priority Date: 09/19/2007
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Inventors: Folden, Thomas Irvin, Crnkovich, Martin Joseph, Weaver, Colin, Kotsos, Michael Emmanuel, Jensen, Melvin D.
• Primary Examiner(s): Menon, Krishnan S
• Assistant Examiner(s): FITZSIMMONS, ALLISON GIONTA
• Application Number:
  US13/101,500
• Publication Number:
  US 20110210054A1
• Time in Patent Office: 390 Days
• Field of Search: None
• US Class Current: 210/646
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/362261 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362262 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/3627 Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 1/3639 Blood pressure control, pressure transducers specially adapted therefor
• CPC Class Codes: A61M 1/3641 Pressure isolators
• CPC Class Codes: A61M 1/3643 Priming, rinsing before or after use
• CPC Class Codes: A61M 1/3644 Mode of operation
• CPC Class Codes: A61M 2205/123 with incorporated reservoirs
• CPC Class Codes: A61M 2205/705 Testing of filters for leaks
• CPC Class Codes: A61M 2205/7527 liquophilic, hydrophilic
• CPC Class Codes: A61M 2205/7536 allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes
• CPC Class Codes: A61M 2205/7563 with means preventing clogging of filters

Abstract

In general, this disclosure relates to extracorporeal fluid circuits. In some aspects, an air-release device for allowing air to be released from a liquid in extracorporeal circuitry includes an elongate chamber having a bottom region and a top region and a fluid entry port and fluid exit port at or near the bottom region. The air release device also includes a vent structure at or near the top region of the elongate chamber that includes a porous material capable of swelling when moistened such that the vent structure can inhibit liquid from escaping the air-release device during use.

Claims

1. An air-release device for allowing air to be released from a liquid in extracorporeal circuitry, the air-release device comprising:

an elongate chamber having a bottom region and a top region and a fluid entry port and fluid exit port at or near the bottom region;

a vent structure at or near the top region of the elongate chamber, the vent structure comprising

a first porous layer; and

a second porous layer comprising a porous material capable of swelling when moistened such that the vent structure can inhibit liquid from escaping the air-release device during use; and

a microporous membrane adjacent the vent structure at or near the top region of the elongate chamber such that liquid can be passed through the elongate chamber from the entry port to the exit port so as to at least partially fill the elongate chamber with the liquid while air exits the chamber via the microporous membrane and the vent structure,

wherein the first porous layer is disposed between the micro-porous membrane and the second porous layer.

2. The air-release device of claim 1, wherein the vent structure has an average pore size of about 15 microns to about 45 microns.

3. The air-release device of claim 1, wherein the vent structure includes polyethylene, polypropylene or polystyrene.

4. The air-release device of claim 1, wherein the vent structure includes carboxymethylcellulose.

5. The air-release device of claim 1, wherein the vent structure includes a blend of polyethelene and carboxymethylcellulose.

6. The air-release device of claim 1, wherein the vent structure has a thickness greater than a thickness of the micro-porous membrane.

7. The air-release device of claim 1, wherein the micro-porous membrane has an average pore size of about 0.05 microns to about 0.45 microns.

8. The air-release device of claim 1, further comprising a ring into which the micro-porous membrane is press-fit, wherein the ring surrounds the vent structure and retains the vent structure adjacent to the micro-porous membrane.

9. The air-release device of claim 1, wherein the microporous membrane includes a hydrophobic material.

10. The air-release device of claim 1, wherein the first porous layer comprises a porous material capable of swelling when moistened, and the second porous layer is less responsive to moisture than the first porous layer.

11. The air-release device of claim 1, wherein the first porous layer has an average pore size of about 5 microns to about 45 microns.

12. The air-release device of claim 1, wherein the second porous layer has an average pore size of about 15 to about 45 microns.

13. The air-release device of claim 1, wherein the second porous layer has an average pore size that is greater than an average pore size of the first porous layer.

14. The air-release device of claim 1, wherein the second porous layer comprises about 5% to about 50% by weight carboxymethylcellulose.

15. The air-release device of claim 1, wherein the first porous layer comprises about 0% to about 10% carboxymethylcellulose.

16. The air-release device of claim 1, wherein the first porous layer comprises less than 5% carboxymethylcellulose.

17. The air-release device of claim 1, wherein the microporous membrane forms at least a portion of a top surface of the elongate chamber.

18. The air-release device of claim 1, wherein the fluid entry and exit ports are in a bottom surface of the elongate chamber.

19. The air-release device of claim 1, wherein the bottom region of the chamber is flared such that the bottom region is wider than the top region.

20. The air-release device of claim 1, wherein the exit port is substantially vertically aligned with the vent structure during use, and the entry port is horizontally offset from the vent structure during use.

21. The air-release device of claim 1, wherein the chamber has a height of about three inches to about four inches.

22. The air-release device of claim 1, wherein the extracorporeal circuitry is hemodialysis extracorporeal circuitry.

23. A dialysis system, comprising:

a dialysis machine body;

a pump on the machine body;

fluid circuitry in fluid communication with the pump, wherein the pump is configured to push fluid through the circuitry;

an air release device in fluid communication with the fluid circuitry, the air release device being positioned adjacent to the machine body, the air release device comprising

an elongate chamber having a bottom region and a top region and a fluid entry port and fluid exit port at or near the bottom region;

a vent structure at or near the top region of the elongate chamber, the vent structure comprising

a first porous layer; and

a second porous layer comprising a porous material capable of swelling when moistened such that the vent structure can inhibit liquid from escaping the air-release device during use; and

a microporous membrane adjacent the vent structure at or near the top region of the elongate chamber such that liquid can be passed through the elongate chamber from the entry port to the exit port so as to at least partially fill the elongate chamber with the liquid while air exits the chamber via the microporous membrane and the vent structure,

wherein the first porous layer is disposed between the micro-porous membrane and the second porous layer.