System and method for estimating volume of activation in tissue

• US 8,190,250 B2
• Filed: 10/14/2010
• Issued: 05/29/2012
• Est. Priority Date: 10/15/2009
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Moffitt, Michael A.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): LEE, YUN H
• Application Number:
  US12/904,967
• Publication Number:
  US 20110093045A1
• Time in Patent Office: 593 Days
• Field of Search: 600/378, 600/544, 607/115, 607/116, 607/148, 128/898
• US Class Current: 600/544
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators

Abstract

A system for a neurostimulation device comprises at least one processor configured for estimating at a plurality of spatial points a respective plurality of electrical field vectors resulting from a stimulation lead operating in accordance with a set of stimulation parameters, determining an amplitude of each electrical field vector and an angle between each electrical field vector and a vector aligned with an axis of the stimulation lead, and estimating a tissue of volume activation about the stimulation lead based on the determined amplitude and angle of each electrical field vector.

Claims

1. A system for a neurostimulation device having a stimulation lead, comprising:

at least one processor configured for estimating at a plurality of spatial points a respective plurality of electrical field vectors resulting from the stimulation lead operating in accordance with a set of stimulation parameters, determining an amplitude of each electrical field vector and an angle between each electrical field vector and a vector aligned with an axis of the stimulation lead, and estimating a tissue of volume activation about the stimulation lead based on the determined amplitude and angle of each electrical field vector.

2. The system of claim 1, wherein the at least one processor is configured for determining the extent to which each electrical field vector acts as a cathode or an anode relative to the stimulation lead based on the angle between the respective electrical field vector and the vector aligned with the axis of the stimulation lead.

3. The system of claim 1, wherein the at least one processor is further configured for determining signs of a directional component and a positional component of each electrical field vector along a coordinate axis, and estimating the tissue volume of activation about the stimulation lead further based on the determined signs of the directional component and positional component of each electrical field vector relative to a coordinate axis perpendicular to the axis of the stimulation lead.

4. The system of claim 3, wherein the at least one processor is configured for determining whether the electrical field vector acts as a cathode or acts as an anode relative to the stimulation lead based on the signs of the directional component and positional component of each electrical field vector relative to the coordinate axis.

5. The system of claim 3, further comprising memory storing a function having an amplitude, an angle, a sign of a directional component, and a sign of a positional component of an electrical field vector as an input, and an indicator of whether nerve tissue is activated at the position of the electrical field vector as an output, wherein the at least one processor is configured for estimating the tissue volume of activation based on the function.

6. The system of claim 1, wherein the at least one processor is configured for modeling the stimulation lead, and for estimating the plurality of electrical field vectors based on the modeled stimulation lead.

7. The system of claim 1, further comprising a display device configured for displaying the tissue volume of activation to a user.

8. The system of claim 1, further comprising telemetry circuitry, wherein the at least one processor is further configured for programming the neurostimulation device with a set of stimulation parameters via the telemetry circuitry.