Wide-field retinal prosthesis

• US 8,190,266 B2
• Filed: 02/15/2006
• Issued: 05/29/2012
• Est. Priority Date: 02/15/2006
• Status: Expired due to Fees

• Current Assignee: Doheny Eye Institute
• Original Assignee: Doheny Eye Institute
• Inventors: Ameri, Hossein, Weiland, James, Eckhard, Helmut, Ufer, Stefan, Ratanapakorn, Tanapat, Humayun, Mark
• Primary Examiner(s): Lavert, Nicole F
• Application Number:
  US11/355,094
• Publication Number:
  US 20070191909A1
• Time in Patent Office: 2,295 Days
• Field of Search: 607/141, 607/54, 600/383, 600/393
• US Class Current: 607/54
• CPC Class Codes: A61N 1/0543 Retinal electrodes
• CPC Class Codes: A61N 1/36046 of the eye

Abstract

A wide-filed retinal prosthesis enables an increased field of vision with a relatively small scleral incision. The retinal prosthesis includes a flexible substrate comprising a central member and at least one wing, with an array of electrodes disposed therein that are configured to stimulate the central and peripheral nerves of the retina.

Claims

1. Apparatus for stimulating vision, the apparatus configured to receive stimulation signals, the apparatus comprising:

A. a flexible electrode substrate configured for implantation on a retina, the substrate comprising a central member and at least one wing extending along at least a portion of a peripheral edge of the central member and defining a gap therebetween; and

B. an array of retina stimulators disposed within the flexible substrate and configured to stimulate the retina in response to receipt of the stimulation signals, wherein one or more retina stimulators are disposed on the at least one wing and one or more retina stimulators are disposed on the central member.

2. The apparatus of claim 1, wherein the substrate and array of retina stimulators are further configured to compact to fit within a scleral incision of less than the width of the substrate.

3. The apparatus of claim 1, wherein the substrate and array of retina stimulators are configured to compact to fit within a scleral incision of not more than about one half of the width of the substrate.

4. The apparatus of claim 1, wherein the substrate and array of retina stimulators are configured to be compacted to fit within a scleral incision of not more than about one quarter of the width of the substrate.

5. The apparatus of claim 1, wherein the substrate and array of retina stimulators are configured to be rolled or folded.

6. The apparatus of claim 5, wherein the substrate and array of retina stimulators are configured to be loaded into a tube configured to insert the substrate and array of retina stimulators through a scleral incision having a width less than a width of the substrate.

7. The apparatus of claim 1, wherein the apparatus stimulates vision in a field of view of up to about 60 degrees.

8. The apparatus of claim 1, wherein the at least one wing comprises a first wing and a second wing and the gap includes a first gap defined between the first wing and a portion of the central member and a second gap defined between the second wing and the central member.

9. The apparatus of claim 8, wherein the central member is substantially disk shaped and first wing and the second wing are substantially arc shaped.

10. The apparatus of claim 8, wherein at least one of the first gap and second gap are substantially uniform in width.

11. The apparatus of claim 8, wherein at least one of the first gap and second gap are substantially V-shaped.

12. The apparatus of claim 1, wherein the at least one wing comprises a first wing having a first distal end and a second wing having a second distal end, and the first wing and second wing are disposed to form a wing gap between the first distal end and the second distal end.

13. The apparatus of claim 12, wherein the wing gap is narrowest closest to the central member.

14. The apparatus of claim 12, wherein the central member extends into the wing gap.

15. The apparatus of claim 1, wherein the at least one wing comprises at least four wings, including two internal wings and two external wings, wherein the two internal wings are disposed between the central member and the two external wings.

16. The apparatus of claim 1, wherein the substrate covers an area of the eye of about 80 mm².

17. The apparatus of claim 1, wherein the substrate and array of retina stimulators is not thicker than about 15 microns.

18. The apparatus of claim 1, wherein the substrate is thinnest at its edges.

19. The apparatus of claim 1, wherein the substrate includes a skeleton comprising a rigid portion disposed proximate to the middle of at least one of the central member or the at least one wing.

20. The apparatus of claim 1, wherein at least one tack hole is formed in the substrate, wherein the at least one tack hole is configured to enable tacking of the apparatus to the retina with a retinal tack.

21. The apparatus of claim 1, wherein array of retina stimulators comprises an array of electrodes.

22. The apparatus of claim 1, wherein the apparatus includes means for receiving the stimulation signals via a wireless transmission path.

23. The apparatus of claim 1, wherein the apparatus includes a multilayer cable as means for receiving the stimulation signals.

24. The apparatus of claim 1, wherein the central member includes a base and the at least one wing extends from the base.