Method and apparatus for electrochemical analysis
First Claim
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1. An electrochemical device, comprising:
- a first electrically conductive layer including a first electrode area and an opposing second electrically conductive layer including a second electrode area, wherein at least one of the first or second electrically conductive layers comprises an electrically conductive material and an insulating material, wherein the electrically conductive material is coextensive with the insulating material;
a spacing layer positioned between the first and second electrically conductive layers and a sealing layer positioned adjacent to one of the first and second electrically conductive layers;
an electrochemical cell defined by the first and second electrically conductive layers, and an opening in the spacing layer;
an immunological cell defined by one of the first and second electrically conductive layers, the sealing layer, and an opening in the spacing layer and at least one of the first and second electrically conductive layers;
first and second electrical contact areas spaced laterally from the electrochemical cell; and
a sample passageway between the electrochemical cell and the immunological cell, wherein a sample can flow from the immunological cell to at least a portion of the electrochemical cell through the sample passageway.
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Abstract
Electrochemical sensors for investigating a physiological sample and methods of manufacture are disclosed. The sensor includes an electrochemical reaction cell, having electrodes and a reagent, and laterally spaced electrical contact points for electrically communication with a meter. Further described herein is a multi-chambered sensor having an electrochemical reaction cell and an immunological cell. The multi-chambered cell can also include a pre-chamber.
46 Citations
19 Claims
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1. An electrochemical device, comprising:
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a first electrically conductive layer including a first electrode area and an opposing second electrically conductive layer including a second electrode area, wherein at least one of the first or second electrically conductive layers comprises an electrically conductive material and an insulating material, wherein the electrically conductive material is coextensive with the insulating material; a spacing layer positioned between the first and second electrically conductive layers and a sealing layer positioned adjacent to one of the first and second electrically conductive layers; an electrochemical cell defined by the first and second electrically conductive layers, and an opening in the spacing layer; an immunological cell defined by one of the first and second electrically conductive layers, the sealing layer, and an opening in the spacing layer and at least one of the first and second electrically conductive layers; first and second electrical contact areas spaced laterally from the electrochemical cell; and a sample passageway between the electrochemical cell and the immunological cell, wherein a sample can flow from the immunological cell to at least a portion of the electrochemical cell through the sample passageway. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. An electrochemical device, comprising:
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a first electrically conductive layer including a first electrode area and an opposing second electrically conductive layer including a second electrode area, wherein at least one of the first or second electrically conductive layers comprises an electrically conductive material and an insulating material, wherein the electrically conductive material is coextensive with the insulating material; a spacing layer positioned between the first and second electrically conductive layers and a sealing layer positioned adjacent to one of the first and second electrically conductive layers; an electrochemical cell defined by the first and second electrically conductive layers, and an opening in the spacing layer; an immunological cell defined by the first and second electrically conductive layers, and an opening in the spacing layer; a pre-chamber defined by one of the first and second electrically conductive layers, the sealing layer, and an opening in at least one of the spacing layer and at least one of the first and second electrically conductive layers; first and second electrical contact areas spaced laterally from the electrochemical cell; and a sample passageway between the electrochemical cell and the immunological cell, wherein a sample flows from the immunological cell to at least a portion of the electrochemical cell through the sample passageway.
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18. An electrochemical device, comprising:
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a first electrically conductive layer including a first electrode area and an opposing second electrically conductive layer including a second electrode area, wherein at least one of the first or second electrically conductive layers comprises an electrically conductive material and an insulating material, wherein the electrically conductive material is coextensive with the insulating material; a spacing layer positioned between the first and second electrically conductive layers and a sealing layer positioned adjacent to one of the first and second electrically conductive layers; a first cell defined by the first and second electrically conductive layers, and an opening in the spacing layer; first and third electrical contact areas in electrical communication with the first electrically conductive layer and a second electrical contact area in electrical communication with the second electrically conductive layer; a second cell defined by one of the first and second electrically conductive layers, the sealing layer, and an opening in the spacing layer and at least one of the first and second electrically conductive layers; and a sample passageway between the first cell and the second cell, wherein a sample flows from the second cell to at least a portion of the first cell through the sample passageway. - View Dependent Claims (19)
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Specification