Flexible circuit electrode array for improved layer adhesion

• US 8,200,338 B2
• Filed: 01/13/2006
• Issued: 06/12/2012
• Est. Priority Date: 12/03/2004
• Status: Active Grant

• Current Assignee: Cortigent Incorporated, Doheny Eye Institute
• Original Assignee: Second Sight Medical Products, Inc. (Vivani Medical, Inc.)
• Inventors: Humayun, Mark S., Grennberg, Robert Jay
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Ghand, Jennifer
• Application Number:
  US11/331,625
• Publication Number:
  US 20060190058A1
• Time in Patent Office: 2,342 Days
• Field of Search: 600/26, 600/27, 600372-397, 607/53, 607/54, 607/116, 607/141, 607/152
• US Class Current: 607/53
• CPC Class Codes: A61N 1/0543 Retinal electrodes
• CPC Class Codes: A61N 1/36046 of the eye

Abstract

Present invention is a method of improving circadian rhythms in blind people by stimulation the visual neural system. Ideally a retinal prosthesis of the type used to restore vision can be used to restore normal circadian rhythms. Additionally, brightness on the prosthesis can be increased in the morning and decreased in the evening to stimulate normal Circadian rhythms. Alternatively, if a retinal prosthesis is not preferable, the retina can be stimulated externally, during the day and not at night. While such eternal stimulation can not produced artificial vision, it can stimulate normal circadian rhythms.

Claims

1. A flexible circuit electrode array adapted to be used with a visual prosthesis, comprising:

a) an insulating polymer layer comprising a top polymer portion and a bottom polymer portion;

b) at least one trace containing a base conducting layer, an intermediate conducting layer and a top conducting layer, embedded in said insulating polymer layer between said top polymer portion and said bottom polymer portion; and

c) at least one electrode connected to said at least one trace through a via in said top polymer portion of said insulating polymer layer, wherein said electrode includes a first electrode portion contacting said trace through said via and a second electrode portion overlapping said trace above said top polymer portion, and wherein a region of said top polymer portion is defined between said trace and said second electrode portion, wherein the first electrode portion is a central electrode portion contacting a corresponding central portion of the trace and the second electrode portion is a peripheral annular-shaped portion overlapping a corresponding peripheral annular-shaped of the trace above said top polymer portion.

2. The flexible circuit electrode array of claim 1 wherein said insulating polymer layer contains polyfluorocarbons, polyethylene, polypropylene, silicone, polyamide, polyimide, liquid crystal polymer, poly-paraxylylene, polyaryletherketone and/or derivatives and/or mixtures thereof.

3. The flexible circuit electrode array of claim 1 wherein said intermediate conducting layer contains platinum, tantalum, iridium, palladium, rhodium, rhenium, gold, chrome, molybdenum, or carbon, or an alloy thereof or a combination of two or more alloys or metal layers thereof.

4. The flexible circuit electrode array of claim 1, wherein the base conducting layer and the top conducting layers of the trace are made of titanium, and the intermediate conducting layer is made of platinum whereby said trace forms a titanium/platinum/titanium film stack.

5. The electrode array of claim 1 wherein the at least one electrode comprises a surface coating, said surface coating having at least 5 times the surface area of that for the corresponding surface area resulting from the basic geometric shape of the electrode.

6. The flexible circuit electrode array of claim 1 wherein the at least one electrode comprises a surface coating, said surface coating being biocompatible.

7. The flexible circuit electrode array of claim 1 wherein the at least one electrode comprises a surface coating, said surface coating having a surface area of less than 500 times the corresponding surface area resulting from the basic geometric shape.

8. The flexible circuit electrode array of claim 1 wherein the at least one electrode comprises a surface coating, said surface coating comprising platinum having a fractal configuration, titanium nitride, iridium oxide, or mixtures thereof.

9. The flexible circuit electrode array of claim 1,

wherein said top polymer portion and said bottom polymer portion are made of different polymers.

10. The flexible circuit electrode array of claim 9, wherein said top polymer portion is made of a polymer softer than the polymer of said bottom polymer portion.

11. The flexible circuit electrode array of claim 10, wherein said bottom polymer portion is made of polyimide and said top polymer portion is made of silicone.

12. The flexible circuit electrode array of claim 1 wherein the trace separates the electrode from the bottom polymer portion.

13. The flexible circuit electrode array of claim 1, wherein the electrode protrudes from the top polymer portion.

14. The flexible circuit electrode array according to claim 1, wherein the electrode is thicker than the trace.

15. The flexible circuit electrode array according to claim 1, wherein the trace is wider at the electrode than it is along the rest of its length.

16. The flexible circuit electrode array according to claim 1, wherein the second electrode portion defines a circle coaxial to the via around the central electrode portion and the peripheral annular-shaped portion of the trace defines a circle coaxial to the via around the central portion of the trace.

17. A flexible circuit electrode array adapted to be used with a visual prosthesis, comprising:

a) an insulating polymer layer comprising a top polymer portion and a bottom polymer portion;

b) at least one trace containing a base conducting layer, an intermediate conducting layer and a top conducting layer, embedded in said insulating polymer layer between said top polymer portion and said bottom polymer portion; and

c) at least one electrode connected to said at least one trace through a via in said top polymer portion of said insulating polymer layer, wherein said electrode includes a first electrode portion contacting said trace through said via and a second electrode portion overlapping said trace above said top polymer portion, and wherein a region of said top polymer portion is defined between said trace and said second electrode portion, wherein the trace includes a plate-shaped trace portion, and wherein the first electrode portion is a central portion contacting a central portion of the plate-shaped trace portion, and the second electrode portion is a perimeter portion overlapping a perimeter portion of the plate-shaped trace portion above said top polymer portion, the perimeter portion of the plate-shaped trace portion defining a closed line portion around the central portion of the plate-shaped trace portion.

18. The flexible circuit electrode array according to claim 17, wherein the perimeter portion of the plate-shaped trace portion is a ring-shaped or annular-shaped portion.