System and method for generating and using cardiac ischemia diagnostics based on arrhythmia precursors and arrhythmia episodes

• US 8,204,592 B1
• Filed: 12/03/2007
• Issued: 06/19/2012
• Est. Priority Date: 12/03/2007
• Status: Expired due to Fees

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Ostrow, Eliot L., Snell, Jay, Min, Xiaoyi
• Primary Examiner(s): Patel, Niketa
• Assistant Examiner(s): Stoklosa, Joseph
• Application Number:
  US11/949,532
• Time in Patent Office: 1,660 Days
• Field of Search: 600508-509, 600/513, 600/515, 607/9, 607/14
• US Class Current: 607/14
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/37258 Alerting the patient
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 20/30 relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

Techniques are described for generating diagnostic information to aid in determining whether cardiac ischemia within a patient is clinically actionable. In one example, a pacemaker or implantable cardioverter/defibrillator (ICD) detects information pertaining to arrhythmia precursors and to episodes of sustained arrhythmias, as well as information pertaining to episodes of cardiac ischemia. The implanted device then correlates the arrhythmia precursors and the sustained arrhythmias with the episodes of cardiac ischemia so as to generate diagnostics permitting a physician reviewing the diagnostics to determine whether the ischemia is clinically actionable. In some implementations, the diagnostics are instead generated by an external system based on raw data provided by the implanted device. In some implementations, the device itself determines whether the ischemia is clinically actionable and automatically controls therapy or generates warning signals accordingly.

Claims

1. A method for use with an implantable medical device for implant within a patient, comprising:

detecting arrhythmia precursor events within the patient wherein the arrhythmia precursor events comprise one or more of premature ventricular contractions and episodes of non-sustained ventricular tachycardia;

detecting episodes of cardiac ischemia within the patient;

generating diagnostics relating the arrhythmia precursor events with the episodes of cardiac ischemia and distinguishing clinically actionable ischemia events from non-clinically actionable ischemia events; and

controlling at least one device function based on the diagnostics, wherein the at least one device function comprising generating a warning signal if the episodes of cardiac ischemia happen absent one or more arrhythmia precursor events corresponding with the non-clinically actionable ischemia events, and a second therapy based function different from the first function if the episodes of cardiac ischemia happen coincident with one or more arrhythmia precursor events corresponding with the clinically actionable ischemia events.

2. The method of claim 1 wherein detecting arrhythmia precursor events within the patient includes detecting on one or more supraventricular arrhythmia precursors including premature atrial contractions (PACs) and episodes of non-sustained supraventricular tachycardia (SVT).

3. The method of claim 1 wherein detecting arrhythmia precursor events within the patient further includes detecting and distinguishing lone precursor events, couplets of precursor events and runs of precursor events having three or more events in sequence.

4. The method of claim 1 wherein detecting episodes of cardiac ischemia within the patient includes detecting at least one morphological value representative of a likelihood of an ischemic episode and determining whether the value exceeds at least one predetermined threshold representative of an ischemic episode.

5. The method of claim 1 wherein generating diagnostics relating arrhythmia precursor events with episodes of cardiac ischemia includes

generating diagnostics representative of arrhythmia precursor events occurring during episodes of cardiac ischemia, and

generating diagnostics representative of arrhythmia precursor events occurring during periods of time without cardiac ischemia.

6. The method of claim 1 wherein controlling at least one device function based on the diagnostics includes one or more of:

controlling the recording of the diagnostics within the device and controlling the transmission of the diagnostics to an external device.

7. The method of claim 1 wherein controlling at least one device function based on the diagnostics includes controlling therapy delivered to the patient by the implanted device.