Devices, systems and methods for medicament delivery

• US 8,206,360 B2
• Filed: 06/04/2010
• Issued: 06/26/2012
• Est. Priority Date: 02/01/2005
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Intelliject Incorporated
• Inventors: Edwards, Eric Shawn, Edwards, Evan Thomas, Licata, Mark J., Meyers, Paul F., Weinzierl, David A.
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Schmidt, Emily
• Application Number:
  US12/794,020
• Publication Number:
  US 20100309012A1
• Time in Patent Office: 753 Days
• Field of Search: 604/65, 604/67, 604/110, 604/131, 604/141, 604/189, 604/192
• US Class Current: 604/192
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2205/587 Lighting arrangements
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 35/00 Devices for applying media, e.g. remedies, on the human body devices for handling toiletry or cosmetic substances A45D; absorbent pads, e.g. swabs, A61F13/15
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2046 Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/3234 Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user
• CPC Class Codes: A61M 5/326 : Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/3287 : Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: A61M 5/5086 : for indicating if defective, used, tampered with or unsterile
• CPC Class Codes: G16H 20/13 : delivered from dispensers
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16Z 99/00 : Subject matter not provided for in other main groups of this subclass

Abstract

An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.

Claims

1. An apparatus, comprising:

a housing;

a medicament container at least partially disposed within the housing;

a delivery mechanism configured to produce a force to deliver a medicament from the medicament container;

an electronic circuit system coupled to the housing, the electronic circuit system configured to produce an electronic output when the delivery mechanism is actuated;

an actuator configured to be moved relative to the housing to actuate the delivery mechanism, the actuator defining an opening through which the medicament is delivered from the medicament container;

a lock member coupled to a portion of the actuator to limit movement of the actuator; and

a cover member movably coupled to the housing, a first portion of the cover member disposed between a terminal of a power source and the electronic circuit system when the cover member is in a first position, a second portion of the cover member disposed about a portion of the actuator to cover the opening when the cover member is in the first position, the second portion of the cover member disposed about a portion of the lock member when the cover member is in the first position, the first portion spaced apart from the terminal of the power source such that the electronic circuit system is electrically coupled to the power source when the cover member is in a second position, the second portion spaced apart from the actuator when the cover member is in the second position.

2. The apparatus of claim 1, wherein the power source is a battery.

3. The apparatus of claim 1, wherein:

the electronic circuit system is configured to produce a first recorded speech output when the cover member is moved between the first position and the second position; and

the electronic output is a second recorded speech output.

4. The apparatus of claim 1, wherein:

the second portion of the cover member is in contact with a delivery member through which the medicament is delivered from the medicament container, when the cover member is coupled to the housing; and

the second portion of the cover member is spaced apart from the delivery member when the cover member is removed from the housing.

5. The apparatus of claim 1, further comprising:

a needle configured to be in fluid communication with the medicament container, the second portion of the cover member including a needle sheath being disposed about at least a portion of the needle when the cover member is in the first position, the needle sheath disposed apart from the needle when the cover member is in the second position.

6. The apparatus of claim 1, wherein:

the electronic circuit system includes a switch, the electronic circuit system configured to produce the electronic output when the switch is actuated, the actuator configured to actuate the switch when the actuator is moved relative to the housing; and

the second portion of the cover member is engaged with the actuator when the cover member is in the first position to limit movement of the actuator.

7. The apparatus of claim 1, wherein the medicament container contains epinephrine.

8. The apparatus of claim 1, wherein the first portion of the cover member and the second portion of the cover member are monolithically constructed.

9. The apparatus of claim 1, wherein:

the actuator is coupled to a distal end portion of the housing; and

the second portion of the cover member is disposed about at least a portion of a distal end surface of the actuator when the cover member is in the first position.

10. An apparatus, comprising:

a housing;

a medicament container at least partially disposed within the housing;

an actuator configured to be moved relative to the housing to initiate delivery of a medicament from the medicament container, the actuator defining an opening through which the medicament is delivered from the medicament container;

a lock member coupled to a portion of the actuator to limit movement of the actuator;

an electronic circuit system coupled to the housing, the electronic circuit system configured to produce an electronic output when the actuator is moved relative to the housing; and

a cover member movably coupled to the housing, a first portion of the cover member electrically isolating the electronic circuit system from a power source when the cover member is in a first position, a second portion of the cover member disposed about a portion of the actuator to cover the opening and about a portion of the lock member when the cover member is in the first position, the first portion disposed apart from the power source and the second portion disposed apart from the actuator when the cover member is in a second position.

11. The apparatus of claim 10, wherein:

the electronic circuit system is configured to produce a first recorded speech output when the cover member is moved between the first position and the second position; and

the electronic output includes a second recorded speech output.

12. The apparatus of claim 10, wherein:

the power source is a battery; and

the first portion of the cover member is disposed between a terminal of the battery and the electronic circuit system when the cover member is in the first position.

13. The apparatus of claim 10, wherein:

the electronic circuit system includes a switch, the electronic circuit system configured to produce the electronic output when the switch is actuated;

the actuator is configured to actuate the switch when the actuator is moved relative to the housing; and

the second portion of the cover member is engaged with the actuator when the cover member is in the first position such that movement of the actuator relative to the housing is limited.

14. The apparatus of claim 10, wherein:

the electronic circuit system includes a first switch, a second switch and a speaker, the electronic circuit system configured to produce a first recorded speech output via the speaker when the first switch is actuated and a second recorded speech output via the speaker when the second switch is actuated, the electronic output including the second recorded speech output; and

the lock member is engaged with the portion of the actuator when the lock member is in a first lock member position, the lock member disposed apart from the actuator when the lock member is in a second lock member position, the lock member configured to actuate the first switch when the lock member is moved from the first lock member position to the second lock member position;

the first portion of the cover member disposed between a terminal of the power source and the electronic circuit system and the second portion of the cover member configured to limit movement of the lock member when the cover member is in the first position; and

the actuator configured to actuate the second switch when the actuator is moved relative to the housing.

15. The apparatus of claim 10, wherein the medicament container contains epinephrine.

16. An apparatus, comprising:

a housing;

a medicament container at least partially disposed within the housing;

an actuator configured to be moved relative to the housing to initiate delivery of a medicament from the medicament container through an opening defined by a distal end portion of the housing;

a lock member coupled to a portion of the actuator to limit movement of the actuator;

an electronic circuit system coupled to the housing, the electronic circuit system configured to produce an electronic output when the actuator is moved relative to the housing; and

a cover member including a first portion and a second portion, the first portion disposed between a terminal of power source and the electronic circuit system when the cover member is coupled to the housing, the second portion disposed about a portion of the actuator and configured to cover the opening and about a portion of the lock member when the cover member is coupled to the housing, the terminal of the power source in contact with the electronic circuit system when the cover member is removed from the housing.

17. The apparatus of claim 16, wherein the cover member is configured to limit movement of the actuator when the second portion is disposed about the portion of the actuator.

18. The apparatus of claim 16, wherein:

the electronic circuit system is configured to produce a first recorded speech output when the cover member is removed from the housing; and

the electronic output is a second recorded speech output.

19. The apparatus of claim 16, wherein:

the electronic circuit system is configured to produce a first recorded speech output when the cover member is removed from the housing; and

the lock member is engaged with the portion of the actuator when the lock member is in a first lock member position, the lock member disposed apart from the actuator when the lock member is in a second lock member position, the electronic circuit system configured to produce a second recorded speech output when the lock member is moved from the first lock member position to the second lock member position,

the electronic output includes a third recorded speech output.

20. The apparatus of claim 16, wherein the first portion of the cover member and the second portion of the cover member are monolithically constructed.

21. The apparatus of claim 16, further comprising:

a needle configured to be in fluid communication with the medicament container, the needle configured to extend through the opening in response to movement of the actuator such that the medicament is delivered via the needle.