Method of using spinal cord stimulation to treat gastrointestinal and/or eating disorders or conditions

• US 8,214,047 B2
• Filed: 09/26/2005
• Issued: 07/03/2012
• Est. Priority Date: 09/27/2004
• Status: Active Grant

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Inventors: Pyles, Stephen, Hoare, Rohan
• Primary Examiner(s): BOCKELMAN, MARK
• Application Number:
  US11/234,960
• Publication Number:
  US 20060074456A1
• Time in Patent Office: 2,472 Days
• Field of Search: 607 40- 41, 607/117
• US Class Current: 607/40
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36085 Eating disorders or obesity
• CPC Class Codes: A61N 1/36167 Timing, e.g. stimulation onset
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer

Abstract

The present invention involves a method and a system for using electrical stimulation to treat gastrointestinal and/or eating disorders. More particularly, the method comprises surgically implanting an electrical stimulation lead that is in communication with predetermined thoracic vertebral segments to cause spinal nervous tissue stimulation, thus treating a wide variety of gastrointestinal disorders.

Claims

1. A method of treating an eating disorder, comprising:

implanting an electrical lead within the thoracic T5, T5/T6 or T6 epidural space of the spinal cord of a patient;

selecting a plurality of operating parameters for an electrical spinal cord stimulation system that are effective for treating the eating disorder;

programming the electrical spinal cord stimulation system according to the plurality of operating parameters; and

treating the patient'"'"'s eating disorder by increasing gastric motility by activating the electrical spinal cord stimulation system to deliver electrical pulses to spinal nervous tissue within the thoracic T5, T5/T6 or T6 epidural space of the wherein gastric function is normalized in the patient.

2. The method of claim 1 wherein the eating disorder is selected from the group consisting of obesity, anorexia nervosa, and bulimia nervosa.

3. The method of claim 1 wherein the electrical spinal cord stimulation system delivers electrical pulses on a temporary basis in response to receiving an initiation signal from an external control device operated by the patient.

4. The method of claim 3 wherein the patient uses the external control device to deliver electrical pulses beginning immediately before the patient begins eating.

5. The method of claim 3 wherein the patient uses the external control device to deliver electrical pulses beginning immediately before the patient begins eating, during ingestion of food, or after ingestion of food.

6. The method of claim 1 wherein the plurality of operating parameters include a pulse amplitude parameter, a pulse width parameter, a pulse frequency parameter or a combination thereof.

7. The method of claim 6 wherein the lead comprises a plurality of electrodes and the plurality of operating parameters include an electrode configuration.

8. The method of claim 1 wherein the pulse frequency parameter is within the range of 10-350 Hz.

9. The method of claim 1 wherein the selecting comprises:

temporarily delivering electrical pulses according to the plurality of operating parameters to the electrode adjacent to the nerve tissue within the thoracic vertebral segment; and

monitoring gastric activity that occurs while the temporarily delivering is performed.

10. The method of claim 9 wherein the monitoring comprises:

determining gastric motility by measuring pressure generated by contraction of muscles of the stomach and/or small intestine.

11. The method of claim 1 wherein activating the electrical spinal cord stimulation to deliver electrical pulses to the electrical lead results in the patient experiencing satiety.

12. The method of claim 1 wherein activating the electrical spinal cord stimulation to deliver electrical pulses to the electrical lead increases expression of neurotransmitters or neuropeptides.