Methods of treating skin disease, scalp disease, sensitive skin or suppressing hair loss with microbubble washing compositions

• US 8,216,557 B2
• Filed: 05/04/2009
• Issued: 07/10/2012
• Est. Priority Date: 10/06/2006
• Status: Active Grant

• Current Assignee: Thales SA, TOWA Enzyme Co., Ltd.
• Original Assignee: Thales SA, TOWA Enzyme Co., Ltd.
• Inventors: Miyazaki, Kazuo, Fujikawa, Susumu
• Primary Examiner(s): Skowronek, Karlheinz R
• Assistant Examiner(s): GUDIBANDE, SATYANARAYAN R
• Application Number:
  US12/435,252
• Publication Number:
  US 20090214512A1
• Time in Patent Office: 1,163 Days
• Field of Search: None
• US Class Current: 424/70.1
• CPC Class Codes: A01K 13/001 Washing, cleaning, or drying devices for veterinary purposes A61D7/00, A61D11/00
• CPC Class Codes: A61K 8/046 Aerosols; Foams
• CPC Class Codes: A61K 8/66 Enzymes
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/14 for baldness or alopecia
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations
• CPC Class Codes: A61Q 5/02 Preparations for cleaning the hair

Abstract

The present invention provides a microbubble washing composition for washing a human body or an animal, a microbubble washing method using the microbubble washing composition, and a microbubble washing apparatus suitable for carrying out the method are provided which are capable of safely removing sebum and old keratin adhering to the surfaces of the pores in a short period of time, keeping the skin clean for a long period of time, preventing an odor. Specifically, the present invention provides a microbubble washing composition for washing a human body or an animal including a protease and a lipase, a microbubble washing method for washing a human body or an animal including washing a human body or an animal using a washing liquid containing the washing composition and microbubbles, and a microbubble washing apparatus.

Claims

1. A method of removing sebum, old keratin, dirt, fallen hair, dandruff, or alleviating itching, which comprises:

providing a liquid washing composition comprising at least one protease, at least one lipase and at least one alkali metal salt,

adding microbubbles to the liquid composition to form a microbubble solution or adding the liquid composition into a microbubble apparatus to introduce microbubbles into the liquid composition to form a microbubble solution, and

washing the skin of a subject in need thereof with an effective amount of the microbubble solution thereby removing sebum, old keratin, dirt, fallen hair, dandruff or alleviating the itching,

wherein at least one alkali metal salt is selected from the group consisting of an alkali metal carbonate, an alkali metal hydrogen carbonate, an alkali metal sulfate, an alkali halide, and an alkali metal salt of boron.

2. The method according to claim 1, wherein the liquid washing composition consists essentially of at least one protease, at least one lipase and at least one alkali metal salt.

3. The method according to claim 1, wherein the at least one protease is present in an amount of 0.01 to 0.5 wt % based on the total amount of the composition, and the at least one lipase is present in an amount of 0.1 to 1.0 wt % based on the total amount of the composition.

4. The method according to claim 1, wherein the at least one alkali metal salt is present in an amount of 80 to 99.5 wt % based on the total amount of the composition.

5. The method according to claim 1, wherein the washing liquid composition further comprises at least one silica-based desiccant.

6. The method according to claim 1, wherein a scalp of a human body or fur of an animal is washed on said human body or animal.

7. The method according to claim 1, which further comprises filtering out contaminants released from the subject during the washing step.

8. The method according to claim 1, wherein the microbubbles have a diameter of 50 μ

m or less.

9. The method according to claim 1, wherein the microbubbles are negatively charged.