Evacuation device and method for creating a localized pleurodesis

• US 8,220,460 B2
• Filed: 11/19/2004
• Issued: 07/17/2012
• Est. Priority Date: 11/19/2004
• Status: Expired due to Fees

• Current Assignee: Portaero, Inc
• Original Assignee: Portaero, Inc
• Inventors: Tanaka, Don
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): CARPENTER, WILLIAM R
• Application Number:
  US10/992,864
• Publication Number:
  US 20060107961A1
• Time in Patent Office: 2,797 Days
• Field of Search: 604/27, 604/93.01, 604174-177, 60428801-28804, 604/35, 128/207.14, 128/207.16
• US Class Current: 128/207.14
• CPC Class Codes: A61B 17/3415 for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters A61B17/3417 takes precedence; body piercing catheter guide needles A61M25/06
• CPC Class Codes: A61B 17/3421 Cannulas
• CPC Class Codes: A61M 16/10 Preparation of respiratory gases or vapours
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 16/106 in a path
• CPC Class Codes: A61M 2039/0252 for access to the lungs
• CPC Class Codes: A61M 2039/0276 for introducing or removing fluids into or out of the body
• CPC Class Codes: A61M 2202/0007 introduced into the body
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/03 Gases in liquid phase, e.g. cryogenic liquids
• CPC Class Codes: A61M 2210/101 Pleural cavity
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 39/0247 Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body peritoneal dialysis catheters A61M1/285; tracheostomy devices A61M16/0465; measuring pressure within the body A61B5/03; colostomy devices A61F5/445; gastrotomy feeding tubes A61J15/0015; means for fixing a feeding tube outside of the body A61J15/0053

Abstract

A localized pleurodesis evacuation device may be utilized to prevent a pneumothorax by evacuating the air that leaks into the pleural space. The device may also be utilized to create a localized pleurodesis around an access port so that the lung may be safely accessed.

Claims

1. A method for treating a lung of a patient through a thoracic wall, parietal membrane, pleural cavity, and visceral membrane, the method comprising the steps of:

(a) receiving a device including,

an access port adapted to extend through the thoracic wall and the parietal membrane into the pleural cavity of the patient, the access port having a proximal end, a distal end, and a longitudinal axis;

an evacuation structure adapted to be positioned in the pleural cavity between the parietal membrane and visceral membrane; and

the evacuation structure includes a flat disk with a peripheral edge attached to the distal end of the access port substantially concentric with the longitudinal axis of the access port such that the evacuation structure surrounds the distal end of the access port;

(b) introducing the evacuation structure through the thoracic wall and the parietal membrane such that a proximal end of the access port is located external to the patient, and the distal end of the access port and the evacuation structure are located in the pleural cavity;

(c) evacuating air from the pleural cavity through the evacuation structure and access port so that parietal and visceral membranes contact the evacuation structure;

(d) delivering a chemical agent from the evacuation structure such that the chemical agent is delivered only to a localized region of the parietal and visceral membranes adjacent the evacuation structure which surrounds the distal end of the access tube, to create a localized adhesion between the parietal membrane and visceral membrane restricted to said localized region;

(e) waiting until said localized adhesion has formed; and

(f) introducing an instrument through the access port, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung wherein the evacuation structure comprises a plurality of holes in fluid communication with the access port and extending through the peripheral edge of the flat disk and wherein step (c) comprises evacuating air from the pleural cavity through the plurality of holes in the evacuation structure and through the access port so that parietal and visceral membranes contact the evacuation structure.

2. The method of claim 1, wherein step (d) comprises delivering a chemical pleurodesis agent from the evacuation structure such that the chemical pleurodesis agent is delivered only to said localized region of the parietal and visceral membranes adjacent the evacuation structure which surrounds the distal end of the access tube, to create a localized pleurodesis between the parietal membrane and visceral membrane restricted to said localized region.

3. The method of claim 1, wherein the instrument is a conduit and wherein step (f) comprises introducing the conduit through the access port, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung.

4. The method of claim 1, wherein the instrument is a conduit and wherein step (f) comprises:

(f1) introducing the conduit through the access port, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung; and

(f2) delivering a drug into the lung through the conduit.

5. The method of claim 1, wherein the instrument is a conduit and wherein step (f) comprises:

(f1) introducing the conduit through the access port, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung; and

(f2) permitting gases to escape from the lung through the conduit to reduce hyperinflation of the lung.

6. The method of claim 1, wherein the evacuation structure is absorbable.

7. The method of claim 1, wherein the chemical agent is a chemical pleurodesis agent coated on the evacuation structure.

8. The method of claim 1, wherein step (b) comprises:

(b1) introducing the evacuation structure through the thoracic wall and the parietal membrane such that a proximal end of the access port is located external to the patient and the distal end of the access port and the evacuation structure are located in the pleural cavity; and

(b2) applying an external seal around the access port to seal the access port to skin of the patient.

9. The method of claim 1, wherein step (f) comprises:

introducing an instrument through the access port, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung without causing a pneumothorax.

10. A method for treating a lung of a patient through a thoracic wall, parietal membrane, pleural cavity, and visceral membrane, the method comprising the steps of:

(a) receiving a device including,

an access tube adapted to extend through the thoracic wall and the parietal membrane into the pleural cavity of the patient, the access tube having a proximal end, a distal end, and a lumen;

an evacuation structure adapted to be positioned in the pleural cavity between the parietal membrane and visceral membrane; and

the evacuation structure includes a planar disk with a peripheral edge attached to the distal end of the access tube, and substantially surrounding the lumen and the distal end of the access tube; and

(b) introducing the evacuation structure through the thoracic wall and the parietal membrane such that a proximal end of the access tube is located external to the patient, and the distal end of the access tube and the evacuation structure are located in the pleural cavity;

(c) evacuating air from the pleural cavity through the evacuation structure and access tube so that parietal and visceral membranes contact the evacuation structure;

(d) delivering a pleurodesis agent from the evacuation structure such that the pleurodesis agent is delivered only to a localized region of the parietal and visceral membranes adjacent the evacuation structure which surrounds the distal end of the access tube, to create a localized pleurodesis between the parietal membrane and visceral membrane restricted to said localized region;

(e) waiting until said localized pleurodesis has formed; and

(f) introducing an instrument through the lumen of the access tube, through said localized pleurodesis, through the visceral membrane, and into parenchymal tissue of the lung wherein the evacuation structure comprises a plurality of holes extending through the peripheral edge of the planar disk in fluid communication with the access tube and wherein step (c) comprises evacuating air from the pleural cavity through the plurality of holes in the evacuation structure and through the access tube so that parietal and visceral membranes contact the evacuation structure.

11. The method of claim 10, wherein step (d) comprises:

(d1) delivering the pleurodesis agent through the evacuation structure such that the pleurodesis agent is delivered only to a localized region of the parietal and visceral membranes adjacent the evacuation structure which surrounds the distal end of the access tube, to create a localized pleurodesis between the parietal membrane and visceral membrane restricted to said localized region; and

(d2) evacuating the pleurodesis agent through the evacuation structure.

12. The method of claim 10, wherein the instrument is a conduit and wherein step (f) comprises introducing the conduit through the lumen of the access tube, through said localized pleurodesis, through the visceral membrane, and into parenchymal tissue of the lung.

13. The method of claim 10, wherein the instrument is a conduit and wherein step (f) comprises:

(f1) introducing the conduit through the lumen of the access tube, through said localized pleurodesis, through the visceral membrane, and into parenchymal tissue of the lung; and

(f2) delivering a drug into the lung through the conduit.

14. The method of claim 10, wherein the instrument is a conduit and wherein step (f) comprises:

(f1) introducing the conduit through the lumen of the access tube, through said localized pleurodesis, through the visceral membrane, and into parenchymal tissue of the lung; and

(f2) permitting gases to escape from the lung through the conduit to reduce hyperinflation of the lung.

15. The method of claim 10, wherein the evacuation structure is absorbable.

16. The method of claim 10, wherein the pleurodesis agent is coated on the evacuation structure.

17. The method of claim 10, wherein step (b) comprises:

(b1) introducing the evacuation structure through the thoracic wall and the parietal membrane such that a proximal end of the access tube is located external to the patient and the distal end of the access tube and the evacuation structure are located in the pleural cavity; and

(b2) applying an external seal around the access tube to seal the access tube to skin of the patient.

18. The method of claim 10, wherein step (f) comprises:

introducing an instrument through the lumen of the access tube, through said localized pleurodesis, through the visceral membrane, and into parenchymal tissue of the lung without causing a pneumothorax.

19. A method for treating a lung of a patient through a thoracic wall, parietal membrane, pleural cavity, and visceral membrane, the method comprising the steps of:

(a) receiving a device including,

an access tube adapted to extend through the thoracic wall and the parietal membrane into the pleural cavity of the patient, the access tube having a proximal end, and a distal end;

an evacuation structure adapted to be positioned in the pleural cavity between the parietal membrane and visceral membrane;

the evacuation structure including a flat disk with a peripheral edge wherein the distal end of the access tube is attached to the middle of the flat disk such that the flat disk surrounds the distal end of the access tube, and

the evacuation structure includes a plurality of holes extending through said peripheral edge of said flat disk in fluid communication with the access tube;

(b) introducing the evacuation structure through the thoracic wall and the parietal membrane such that a proximal end of the access tube is located external to the patient, and the distal end of the access tube and the evacuation structure are located in the pleural cavity;

(c) evacuating air from the pleural cavity through the plurality of holes in the evacuation structure and access tube so that parietal and visceral membranes contact the evacuation structure;

(d) delivering a pleurodesis agent from the evacuation structure such that the pleurodesis agent is delivered only to a localized region of the parietal and visceral membranes in contact with the evacuation structure surrounding the distal end of the access tube, to create a localized adhesion between the parietal membrane and visceral membrane restricted to said localized region;

(e) waiting until said localized adhesion has formed; and

(f) introducing an instrument through the access tube, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung wherein step (d) comprises;

(d1) delivering the pleurodesis agent through the evacuation structure such that the pleurodesis agent is delivered only to a localized region of the parietal and visceral membranes in contact with the evacuation structure surrounding the distal end of the access tube, to create a localized pleurodesis between the parietal membrane and visceral membrane restricted to said localized region; and

(d2) evacuating the pleurodesis agent through the plurality of holes in the evacuation structure.

20. The method of claim 19, wherein the instrument is a conduit and wherein step (f) comprises introducing the conduit through the access tube, through the visceral membrane, and into parenchymal tissue of the lung.

21. The method of claim 19, wherein the instrument is a conduit and wherein step (f) comprises:

(f1) introducing the conduit through the access tube, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung; and

(f2) delivering a drug into the lung through the conduit.

22. The method of claim 19, wherein the instrument is a conduit and wherein step (f) comprises:

(f1) introducing the conduit through the access tube, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung; and

(f2) permitting gases to escape from the lung through the conduit to reduce hyperinflation of the lung.

23. The method of claim 19, wherein the evacuation structure is absorbable.

24. The method of claim 19, wherein step (b) comprises:

(b1) introducing the evacuation structure through the thoracic wall and the parietal membrane such that a proximal end of the access tube is located external to the patient and the distal end of the access tube and the evacuation structure are located in the pleural cavity; and

(b2) applying an external seal around the access tube to seal the access tube to skin of the patient.

25. The method of claim 19, wherein step (f) comprises:

introducing an instrument through the access tube, through said localized adhesion, through the visceral membrane, and into parenchymal tissue of the lung without causing a pneumothorax.