Blood sensor and blood examining instrument including same

• US 8,221,336 B2
• Filed: 09/19/2007
• Issued: 07/17/2012
• Est. Priority Date: 09/19/2006
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Corporation (Panasonic Holdings Corporation)
• Inventors: Fujiwara, Masaki, Akiyama, Toshihiro, Hamanaka, Kenichi
• Primary Examiner(s): Szmal, Brian
• Application Number:
  US12/441,638
• Publication Number:
  US 20090318790A1
• Time in Patent Office: 1,763 Days
• Field of Search: 600/583, 600/584, 600/345, 600/347, 606181-183
• US Class Current: 600/584
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14535 for measuring haematocrit
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150954 Means for the detection of operative contact with patient, e.g. by temperature sensitive sensor
• CPC Class Codes: A61B 5/15109 Fully automatically triggered, i.e. the triggering does not require a deliberate action by the user, e.g. by contact with the patient's skin
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/15136 by use of radiation, e.g. laser
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 33/66 involving blood sugars, e.g. galactose

Abstract

A blood sensor comprises a substrate, a spacer attached to the top of the substrate, a cover attached to the top of the spacer. A blood reservoir defined by a substrate hole formed in the substrate. A part of a spacer hole in the spacer and connected to the substrate hole, and a cover hole formed in the cover is connected to the spacer hole. A supply passage is defined by another part of the spacer hole that communicates with the blood reservoir portion, and detection electrodes are formed in the supply passage. The cover projects from the supply passage toward the inside of the blood reservoir portion farther than the substrate and the spacer.

Claims

1. A blood sensor comprising:

a substrate;

a spacer that is configured to be attached on an upper surface of the substrate;

a cover that is configured to be attached on an upper surface of the spacer;

a blood storage that comprises a substrate hole in the substrate, a part of a spacer hole in the spacer and which is configured to be coupled to the substrate hole, and a cover hole which is in the cover and which is configured to be coupled to the spacer hole;

a supply channel comprises another part of the spacer hole and that extends away from the blood storage and is configured to communicate with the blood storage; and

a plurality of detection electrodes on the supply channel,

wherein at least a portion of the edge of the cover hole extends from a supply channel side toward an interior of the blood storage, beyond the edge of the spacer hole and the edge of the substrate hole.

2. The blood sensor according to claim 1, wherein a length of the projection of the cover is greater than a sum of a thickness of the substrate and a thickness of the spacer.

3. The blood sensor according to claim 1, wherein an open area of the cover hole is equal to or less than an open area of the substrate hole and is smaller than an open area of the spacer hole.

4. The blood sensor according to claim 1, wherein at least a portion of the edge of the substrate hole extends from the supply channel side toward the interior of the blood storage, beyond the edge of the spacer hole and is configured to define a space between the substrate and the cover.

5. The blood sensor according to claim 1, wherein:

the substrate hole, the spacer hole of the blood storage, and the cover hole are round;

a diameter of the cover hole is equal to or less than a diameter of the substrate hole and is smaller than a diameter of the spacer hole; and

the centers of the substrate hole, the spacer hole and the cover hole are concentric with each other.

6. The blood sensor according to claim 1, wherein:

the substrate hole, the spacer hole of the blood storage, and the cover hole are round;

a diameter of the cover hole is equal to or less than a diameter of the substrate hole and is smaller than a diameter of the spacer hole;

a centers of the cover hole and the spacer hole are concentric with each other; and

the center of the substrate hole is farther from the supply channel than the center of the spacer hole.

7. The blood sensor according to claim 1, wherein:

the substrate hole, the spacer hole of the blood storage, and the cover hole are round;

a diameter of the substrate hole is larger than a diameter of the cover hole and equal to a diameter of the spacer hole;

centers of the substrate hole and the spacer hole are concentric with each other; and

the center of the cover hole is farther away the supply channel than the center of the substrate hole.

8. The blood sensor according to claim 1, wherein the cover comprises a projection configured to project from the supply channel side toward the interior of the blood storage.

9. The blood sensor according to claim 1, wherein the blood storage is configured to have a negative pressure applied thereto through the cover hole.

10. The blood sensor according to claim 1, wherein:

the substrate, the spacer and the cover comprise a base plate of a polygon;

electrodes are at apexes of the polygon;

the electrodes at the apexes are each configured to be connected with one of the plurality of detection electrodes; and

two of the electrodes at the apexes are connected with the same detection electrode.

11. The blood sensor according to claim 10, wherein the base plate is a regular hexagon.

12. The blood sensor according to claim 1, wherein:

an upper surface of the cover is water-repellent;

an inner surface of the supply channel is hydrophilic; and

a ceiling of the blood storage is less water-repellent than the upper surface of the cover or is less hydrophilic than the inner surface of the supply channel.

13. The blood sensor according to claim 1, wherein a lower surface of the substrate is water-repellent.

14. A blood test apparatus comprising:

a housing;

a cylindrical body at one end of the housing;

a plunger configured to move back and forth inside the cylindrical body;

a lancet that is configured to be detachably held at one end by the plunger and at the other end, is configured to have a puncturing needle attached;

a blood sensor that faces the puncturing needle; and

an electrical circuit that is configured to be connected with the blood sensor,

wherein the blood sensor comprises the blood sensor according to claim 1.

15. The blood test apparatus according to claim 14, wherein:

the blood sensor is configured to be attached to a cylindrical holder to comprise a cartridge; and

the cartridge is configured to be removably attached to the cylindrical body.

16. The blood test apparatus according to claim 15, wherein the holder comprises a transparent or semitransparent member such that an interior of the holder is visible.

17. The blood test apparatus according to claim 14, further comprising negative pressure applier that configured to apply a negative pressure near the blood sensor.

18. The blood test apparatus according to claim 14, wherein the puncturing needle is configured to puncture a skin at a position closer to a supply channel side than the center of a cover hole of the blood sensor.

19. A blood test apparatus comprising:

a housing;

a cylinder body at one end of the housing;

a laser emitting apparatus that is inside the cylinder body;

a blood sensor that is configured to face a laser emitting opening of the laser emitting apparatus; and

an electrical circuit that is configured to be connected with the blood sensor,

wherein the blood sensor comprise the blood sensor according to claim 1.

20. The blood test apparatus according to claim 19, wherein:

the blood sensor is configured to be attached to a cylindrical holder to comprise a cartridge; and

the cartridge is configured to be removably attached to the cylinder body.

21. The blood test apparatus according to claim 20, wherein the holder comprises a transparent or semitransparent member such that an interior of the holder is visible.

22. The blood test apparatus according to claim 19, further comprising a negative pressure applier that is configured to apply a negative pressure near the blood sensor.

23. The blood test apparatus according to claim 19, wherein a laser light that is configured to puncture a skin at a position closer to a supply channel side than the center of a cover hole of the blood sensor.